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http://dx.doi.org/10.5352/JLS.2013.23.3.443

Antimicrobial and Anti-oral Malodor Efficacy of Schizandra chinensis Extracts against Oral Pathogens  

Heo, Nam Suk (Department of Dental Hygiene, Masan University)
Choi, Hye Jung (Department of Biology and Interdisciplinary Program for Biotechnology, Changwon National University)
Hwang, Su Mi (Department of Clinical Pathology, Masan University)
Choi, Young Whan (Department of Horticultural Bioscience, Pusan National University)
Lee, Young Geun (Department of Food Science and Technology, Pusan National University)
Joo, Woo Hong (Department of Biology and Interdisciplinary Program for Biotechnology, Changwon National University)
Publication Information
Journal of Life Science / v.23, no.3, 2013 , pp. 443-447 More about this Journal
Abstract
This study was conducted to investigate the antimicrobial and anti-oral malodor effect of Schizandra chinensis extracts against oral pathogens. S. chinensis methanol (MeOH) extract showed better antimicrobial activities against oral pathogens than the S. chinensis hot water extract did. In particular, ethylacetate (EA) fraction of S. chinensis MeOH extract had the greatest effects against Streptococcus mutans, S. sanguinis, S. salivaris subsp. thermophols and Porphyromons gingivalis. The anti-malodor effect of S. chinensis against the generation of volatile sulfur compounds (VSC), such as hydrogen sulfide, methyl mercaptan, and dimethyl sulfide, was estimated using oral chroma in a practical study. The results showed that 2% MeOH extract of S. chinensis against the production of hydrogen sulfide, methyl mercaptan, and dimethyl sulfide had inhibitions of 91.15, 78.72 and 71.58%, respectively. These results showed that Schizandra chinensis extract had antimicrobial activity against several oral pathogens and exhibited significant effects on the inhibition of VSCs. Thus, Schizandra chinensis extract could be an alternative to available synthetic chemicals and oral hygiene products.
Keywords
Antimicrobial activity; anti-oral malodor effect; Schizandra chinensis; oral pathogens;
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1 McBain, A. J., Bartolo, R. G., Catrenich, C. E., Charbonneau, D., Ledder, R. G. and Gilbert, P. 2003. Exposure of sink drain microcosms to triclosan: population dynamics and antimicrobial susceptibility. Appl Envioron Microbiol 69, 5433-5442.   DOI   ScienceOn
2 Morita, M. and Wang, H. L. 2001. Relationship of sulcular sulfide level and oral malodor in subjects with periodontal disease. J Periodontol 72, 79-84.   DOI   ScienceOn
3 Murray, P. R., Baron, E. J., Pfaller, M. A., Tenover, F. C. and Yolke, R. H. 1999. Manual of Clinical Microbiology, pp. 1527-1539, 7th eds., ASM, Washington DC.
4 Quirynen, M., Zhao, H. and van Steenberghe, D. 2002. Review of the treatment strategies for oral malodour. Clin Oral Investig 6, 1-10.
5 Sanbe, T., Tomofuji, T., Ekuni, D., Azuma, T., Tamaki, N. and Yamamoto, T. 2007. Oral administration of vitamin C prevents alveolar bone resorption induced by high dietary cholesterol in rats. J Periodontol 78, 2165-2170.   DOI   ScienceOn
6 Singleton, V. L. and Rossi, J. A. 1965. Colorimetry of total phenolics with phosphomolibdic-phosphotungtic acid reagents. Am J Enol Vitic 16, 144-158.
7 Woisky, R. G. and Salatino, A. 1998. Analysis of propolis: some parameters and procedures for chemical quality control. J Apic Res 37, 99-105.
8 Choi, H. D., Koh, Y. J., Choi, I, W., Kim, Y. S. and Park, Y. K. 2007. Anticariogenic activity and glucosyltransferase inhibitory effects of extracts from pine needle and twing. Korean J Food Sci Technol 39, 336-341.
9 Yim, S. Y., Lee, Y. J., Lee, Y. K., Jung, S. E., Kim, J. H., Kim, J. E., Kim, H. J., Son, B. G., Park, Y. H., Lee, Y. G., Choi, Y. W. and Hwang, D. Y. 2009. Gomisin N isolated from Schisandra chinensis significantly induces anti-proliferative and pro-apoptotic effects in hepatic carcinoma. Mol Med Report 2, 725-732.
10 Choi, H. J., Heo, N. S., Choi, Y. W., Lee, Y. G., Jeong, Y. K. and Joo, W. H. 2012. Antimicrobial and anti-halitosis effects of Alnus firma extracts. J Life Sci 22, 1071-1076.   과학기술학회마을   DOI   ScienceOn
11 Choi, Y. H., Takamatsu, S., Khan, S. I., Srinivas, P. V., Ferreira, D., Zhao, J. and Khan, I. A. 2006. Schisandrene, a dibenzocyclooctadiene lignan from Schisandra chinensis: structure- antioxidant activity relationships of dibenzocyclooctadiene lignans. J Nat Prod 69, 356-359.   DOI   ScienceOn
12 Kim, B. I., Kim, S. N., Chang, S. Y., Moon, J. T., Kim, Y. S., Hwang, J. K., Jeong, S. H., Kim, M. Y., Kim, H. S. and Kwon, H. K. 2005. A highly selective antibacterial effect of Curcuma xanthorrhiza extract against oral pathogens and clinical effectiveness of a dentifrice containing Curcuma xanthorrhiza extract for controlling bad breath. J Korean Acad Dnet Health 29, 222-237.   과학기술학회마을
13 Eom, G. H. and Kim, J. S. 2007. Deodorizing effect of Cheonggugamrosu. Korean J Orient Int Med 28, 354-362.   과학기술학회마을
14 Goldberg, S., Kozlovsky, A., Gordon, D., Gelernter, I., Sintov, A. and Rosenberg, M. 1994. Cadaverine as a putative component of oral malodor. J Dent Res 73, 1168-1172.
15 Hung, T. M., Na, M. K., Min, B. S., Ngoc, T. M., Lee, I. S., Zhang, X. F. and Bae, K. H. 2007. Acetylcholinesterase inhibitory effect of lignans isolated from Schizandra chinensis. Arch Pharm Res 30, 685-690.   과학기술학회마을   DOI   ScienceOn
16 Chang, H. S. and Choi, Il. 2012. Antimicrobial activities of medicinal herb extracts. J Korean Soc Food Sci Nutr 41, 261-269.   과학기술학회마을   DOI   ScienceOn
17 Chen, N., Chiu, P. Y. and Ko, K. M. 2008. Schisandrin B enhances cerebral mitochondrial antioxidant status and structural integrity, and protects against cerebral ischemia/reperfusion injury in rats. Biol Pharm Bull 31, 1387-1391.   DOI   ScienceOn
18 Kim, H. D. 2011. Deodorizing Effects and Improvements of Oral Hygiene Status by Dentifrice Containing Ginger Extracts. Ph. D. dissertaion, Inje University, Gimhae, Korea.
19 Kim, S. J., Park, I. B., Kang, S. G., Chung, D. O. and Jung, S. T. 2005. Anticariogenic activity and glucosyltransferase inhibition of phenolic compounds. Korean J Food Culture 20, 603-607.   과학기술학회마을