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http://dx.doi.org/10.5352/JLS.2012.22.6.772

Effects of Black Garlic Supplementation and Exercise on TBARS, HSP 70 and COX-2 Expression after High-intensity Exercise  

Baek, Yeong-Ho (Department of Physical Education, Pusan National University)
Lee, Sang-Ho (Department of Physical Education, Pusan National University)
Han, Min-Ho (Department of Biomaterial Control, Graduate School, Dong-Eui University)
Choi, Yung-Hyun (Department of Biomaterial Control, Graduate School, Dong-Eui University)
Kim, Seung-Hyun (Department of Physical Education, Pusan National University)
Kwak, Yi-Sub (Department of Physical Education, Dong-Eui University)
Publication Information
Journal of Life Science / v.22, no.6, 2012 , pp. 772-777 More about this Journal
Abstract
The purpose of this study was to investigate the effects of black garlic supplementation and exercise on TBARS, HSP 70, and COX-2 expression after high-intensity exercise in rats. Twenty-four male Sprague-Dawley rats (4 weeks) were used in this study. Experimental groups were a control group (A, n=6), black garlic supplementation group (B, n=6), exercise group (C, n=6), and black garlic supplementation with exercise group (D, n=6). High-intensity exercise was performed by treadmill running (every 10 min speed increased gradually; 15~24 m/min, $0^{\circ}$ grade) and 2.86 g/kg black garlic for 4 weeks. The findings of this study were as follows: TBARS levels were significantly lower in the D group compared to the other group and B and C groups were significantly lower in TBARS levels than in the A group. HSP 70 expression was lower in the B group compared to the other groups. COX-2 expression has showed a similar expression in all groups. Therefore, it is considered that black garlic intake and exercise may reduce oxidative stress.
Keywords
Black garlic; TBARS; HSP 70; COX-2;
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