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http://dx.doi.org/10.5352/JLS.2012.22.5.687

Opposite Localization of Luteinizing Hormone Receptors and Galectin-3 in Mature Mouse Ovaries  

Kim, Ju-Hwan (College of Veterinary Medicine and Animal Medical Institute, Chonnam National University)
Yang, Mi-Young (College of Veterinary Medicine and Animal Medical Institute, Chonnam National University)
Kim, Sung-Ho (College of Veterinary Medicine and Animal Medical Institute, Chonnam National University)
Kim, Jong-Choon (College of Veterinary Medicine and Animal Medical Institute, Chonnam National University)
Kim, Seung-Joon (College of Veterinary Medicine, Kyungpook National University)
Joo, Hong-Gu (College of Veterinary Medicine, Jeju National University)
Shin, Tae-Kyun (College of Veterinary Medicine, Jeju National University)
Moon, Chang-Jong (College of Veterinary Medicine and Animal Medical Institute, Chonnam National University)
Publication Information
Journal of Life Science / v.22, no.5, 2012 , pp. 687-691 More about this Journal
Abstract
The present study evaluated the localization of luteinizing hormone receptors (LHR) and galectin-3 (Gal-3), a beta-galactoside-binding animal lectin, in the mature mouse ovaries by immunohistochemical analysis. Intense LHR immunoreactivity was detected in the active corpus luteum (CL), whereas expression of Gal-3 was high in the regressing CL and atretic follicle. In the CL of pregnant mice, LHR immunoreactivity was intense, but Gal-3 expression was low. Thus, LHR and Gal-3 had opposite patterns of expression in mature mouse ovaries, suggesting that both proteins have stage-specific expression patterns and are possibly involved in CL formation and regression.
Keywords
Luteinizing hormone receptor; galectin-3; corpus luteum; follicle; mouse ovary;
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