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http://dx.doi.org/10.5352/JLS.2012.22.2.226

Fibrinolytic Activity and Chemical Properties of Cordycepin-Enriched Cordyceps militaris JLM 0636  

Ahn, Hee-Young (Department of Medical Biosciences, Graduate School, Dong-A University)
Lee, Jae-Hong (Department of Medical Biosciences, Graduate School, Dong-A University)
Kang, Min-Jeong (Department of Medical Biosciences, Graduate School, Dong-A University)
Cha, Jae-Young (Technical Research Institute, Daesun Distilling Co., Ltd.)
Cho, Young-Su (Department of Biotechnology, Dong-A University)
Publication Information
Journal of Life Science / v.22, no.2, 2012 , pp. 226-231 More about this Journal
Abstract
The effect of cordycepin-enriched Cordyceps militaris JLM 0636 ($CM{\alpha}$) and Cordyceps militaris (CM) on fibrinolytic activity was investigated. The bioactive compounds and nutritional materials such as polyphenolic compounds, flavonoids, glutathione, minerals, and fatty acids were also measured. Concentrations of polyphenol compounds, flavonoids, and glutathione were higher in $CM{\alpha}$ than that in CM. The major minerals of both materials were K, Ca, Mg, and Na. The major fatty acids of both materials were linolenic acid, linoleic acid, oleic acid, and palmitic acid. Fibrinolytic activity was higher in $CM{\alpha}$ than that in CM. These results may provide the basic data to understand the fibrinolytic activity and bioactive compounds of $CM{\alpha}$.
Keywords
Cordyceps militaris; cordycepin; fibrinolytic activity; glutathione;
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