Involvement of Peroxynitrite in NO Donor-Induced HO-1 Expression in Rat Articular Chondrocytes
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Song, Ju-Dong
(Department of Microbiology and Immunology, Pusan National University School of Medicine)
Kim, Kang-Mi (Department of Microbiology and Immunology, Pusan National University School of Medicine) Kim, Jong-Min (Department of Anatomy and Cell Biology, Dong-A University College of Medicine) Yoo, Young-Hyun (Department of Anatomy and Cell Biology, Dong-A University College of Medicine) Park, Young-Chul (Department of Microbiology and Immunology, Pusan National University School of Medicine) |
1 | Wahl, S. M., N. Cartney-Francis, J. Chan, R. Dionne, L. Ta, and J. M. Qrenstein. 2003. Nitric oxide in experimental joint inflammation. Benefit or detriment? Cells Tissues Organs 174, 26-33. DOI |
2 | Weiss, G., G. Werner-Felmayer, E. R. Werner, K. Grunewald, H. Wachter, and M. W. Hentze. 1994. Iron regulates NO synthase activity by controlling nuclear transcription. J. Exp. Med. 180, 969-976. DOI |
3 | Yu, R., C. Chen, Y. Y. Mo, V. Hebbar, E. D. Owuor, T. H. Tan, and A. N. Kong. 2000. Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism. J. Biol. Chem. 275, 39907-39913. DOI |
4 | Zhang, D. D. and M. Hannink. 2003. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol. Cell Biol. 23, 8137-8151. DOI |
5 | Zhu, H., K. Itoh, M. Yamamoto, J. L. Zweier, and Y. Li. 2005. Role of Nrf2 signaling in regulation of antioxidants and phase2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury. FEBS Lett. 579, 3029-3036. DOI |
6 | Trackey, J. L., T. F. Uliasz, and S. J. Hewett. 2001. SIN-1-induced cytotoxicity in mixed cortical cell culture: Peroxynitrite-dependent and-independent induction of excitotoxic cell death. J. Neurochem. 79, 445-455. |
7 | Vuolteenaho, K., T. Moilanen, R. G. Knowles, and E. Moilanen. 2007. The role of nitric oxide in osteoarthritis. Scand. J. Rheumatol. 36, 247-258. DOI |
8 | Kim, H. J., I. Tsoy, M. K. Park, Y. S. Lee, J. H. Lee, H. G. Seo, and K. C. Chang. 2006. Iron released by sodium nitroprusside contributes to heme oxygenase-1 induction via the cAMP-protein kinase A-mitogen-activated protein kinase pathway in RAW 264.7 cells. Mol. Pharmacol. 69, 1633-1640. DOI |
9 | Kurozumi, R., M. Takahashi, and S. Kojima. 2005. Involvement of mitochondrial peroxynitrite in nitric oxide-induced glutathione synthesis. Biol. Pharm. Bull. 28, 779-785. DOI |
10 | Lee, S. W., Y. S. Song, S. H. Shin, K. T. Kim, Y. C. Park, B. S. Park, I. Yun, K. Kim, S. Y. Lee, W. T. Chung, H. J. Lee, and Y. H. Yoo. 2008. Cilostazol protects rat chondrocytes against nitric oxide-induced apoptosis in vitro and prevents cartilage destruction in a rat model of osteoarthritis. Arthritis Rheum. 58, 790-800. DOI |
11 | Li, M. H., Y. N. Cha, and Y. J. Surh. 2006. Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells. Free Radic. Biol. Med. 41, 1079-1091. DOI |
12 | Mcmillan, K., D. S. Brendt, D. J. Hirsch, S. H. Synder, J. E. Clark, and B. S. Masters. 1992. Cloned, expressed rat cerebellar nitric oxide synthase contains stoichiometric amounts of heme, which binds CO. Proc. Natl. Acad. Sci. USA 89, 11141-11145. DOI |
13 | Naughton, P., R. Foresti, S. K. Bains, M. Hoque, C. J. Green, and R. Motterlini. 2002. Induction of heme oxygenase 1 by nitrosative stress. J. Biol. Chem. 277, 40666-40674. DOI |
14 | Stone, J. R., R. H. Sands, W. R. Dunham, and M. A. Marletta. 1995. Electron paramagnetic resonance spectral evidence for the formation of a pentacoordinate nitrosyl-heme complex on soluble guanylate cyclase. Biochem. Biophys. Res. Commun. 207, 572-577. DOI |
15 | Pi, J., Y. Bai, J. M. Reece, J. Williams, D. Liu, M. L. Freeman, W. E. Fahl, D. Shugar, J. Liu, W. Qu, S. Collins, and M. P. Waalkes. 2007. Molecular mechanism of human Nrf2 activation and degradation: Role of sequential phosphorylation by protein kinase CK2. Free Radic. Biol. Med. 42, 1797-1806. DOI |
16 | Poderoso, J. J., M. C. Carreras, C. Lisdero, N. Riobo, F. Schopfer, and A. Boveris. 1996. Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondrial particles. Arch. Biochem. Biphys. 328, 85-92. DOI |
17 | Polte, T., A. Abate, P. A. Dennery, and H. Schroder. 2000. Heme oxygenase-1 is a cGMP-inducible endothelial protein and mediates the cytoprotective action of nitric oxide. Arterioscler. Thromb. Vasc. Biol. 20, 1209-1215. DOI |
18 | Szabo, C., H. Ischiropoulos, and R. Radi. 2007. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat. Rev. Drug Discov. 6, 662-680. DOI |
19 | Taskiran, D., M. Stefanovic-Racic, H. I. Georgescu, and C. H. Evans. 1994. Nitric oxide mediates suppression of cartilage proteoglycan synthesis by interleukin-1. Biochem. Biophys. Res. Commun. 200, 142-148. DOI |
20 | Niknahad, H. and P. J. O'Brien. 1996. Involvement of nitric oxide in nitroprusside-induced hepatocyte cytotoxicity. Biochem. Pharmacol. 51, 1031-1039. DOI |
21 | Otterbein, L. E., F. H. Bach, J. Alam, M. Soares, M., Tao Lu.H., Wysk, M., R. J. Davis, R. A. Flavell, and A. M. Choi. 2000. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat. Med. 6, 422-428. DOI |
22 | Bouton, C. and B. Demple. 2000. Nitric oxide-inducible expression of heme oxygenase-1 in human cells: translation-independent stabilization of the mRNA and evidence for direct action of nitric oxide. J. Biol. Chem. 275, 32688-32693. DOI |
23 | Denninger, J. W. and M. A. Marletta. 1999. Guanylate cyclase and the .NO/cGMP signaling pathway. Biochim. Biophys. Acta 1411, 334-350. DOI |
24 | Durante, W., M. H. Kroll, N. Christodoulides, K. J. Peyton, and A. I. Schafer. 1997. Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells. Circ. Res. 80, 557-564. DOI ScienceOn |
25 | Foresti, R., P. Sarathchandra, J. E. Clark, C. J. Green, and R. Motterlini. 1999. Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis. Biochem. J. 339, 729-736. DOI |
26 | Hara, E., K. Takahashi, K. Takeda, M. Nakayama, M. Yoshizawa, H. Fujita, K. Shirato, and S. Shibahara. 1999. Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors. Biochem. Pharmacol. 58, 227-236. DOI |
27 | Hartsfield, C. L., J. Alam, J. L. Cook, and A. M. Choi. 1997. Regulation of heme oxygenase-1 gene expression in vascular smooth muscle cells by nitric oxide. Am. J. Physiol. 273, L980-988. |
28 | Alam, J. and J. L. Cook. 2003. Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway. Curr. Pharm. Des. 9, 2499-2511. DOI |
29 | Jackson, R. M., G. Parish, and E. S. Helton. 1998. Peroxynitrite modulates MnSOD gene expression in lung epithelial cells. Free Radic. Biol. Med. 25, 463-472. DOI |
30 | Kang, K. W., S. H. Choi, and S. G. Kim. 2002. Peroxynitrite activates NF-E2-related factor 2/antioxidant response element through the pathway of phosphatidylinositol 3-kinase: the role of nitric oxide synthase in rat glutathione S-transferase A2 induction. Nitric Oxide 7, 244-253. DOI |
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