Deletion Polymorphism of UGT2B17 and Its Relation to Lung Cancer |
Lee, Se-Ra
(Department of Biological Science, Dong-A University)
Ahn, Myoung-Hyun (Department of Biological Science, Dong-A University) Seol, So-Young (Department of Biological Science, Dong-A University) Lee, Ji-Sun (Department of Biological Science, Dong-A University) Chung, Chung-Nam (Department of Biological Science, Dong-A University) Leem, Sun-Hee (Department of Biological Science, Dong-A University) |
1 | Zheng, Z., J. L. Fang, and P. Lazarus. 2002. Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues. Drug Metab. Dispos. 30, 397-403. DOI |
2 | Yang, T. L., X. D. Chen, Y. Guo, S. F. Lei, J. T. Wang, Q. Zhou, F. Pan, Y. Chen, Z. X. Zhang, S. S. Dong, X. H. Xu, H. Yan, X. Liu, C. Qiu, X. Z. Zhu, T. Chen, M. Li, H. Zhang, L. Zhang, B. M. Drees, J. J. Hamilton, C. J. Papasian, R. R. Recker, X. P. Song, J. Cheng, and H. W. Deng. 2008. Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis. Am. J. Hum. Genet. 83, 663-674. DOI |
3 | Yoon, Y. H., S. Y. Seol, J. H. Heo, C. N. Chung, I. H. Park, and S. H. Leem. 2008. Analysis of VNTRs in the solute carrier family 6, member 18 (SLC6A18) and lack of association with hypertension. DNA and Cell Biology 27, 559-567. DOI |
4 | Park, J., L. Chen, L. Ratnashinge, T. A. Sellers, J. P. Tanner, J. H. Lee, N. Dossett, N. Lang, F. F. Kadlubar, C. B. Ambrosone, B. Zachariah, R. V. Heysek, S. Patterson, and J. Pow-Sang. 2006. Deletion Polymorphism of UDP-Glucuronosyltransferase 2B17 and Risk of Prostate Cancer in African American and Caucasian Men. Cancer Epidermiol Biomarkers Prev. 15, 1473-1478. DOI |
5 | Toschi, L. and F. Cappuzzo. 2007. Understanding the new genetics of responsiveness to epidermal growth factor receptor tyrosine kinase inhibitors. Oncologist 12, 211-220. DOI |
6 | Tukey, R. H. and C. P. Strassburg. 2000. Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annu Rev. Pharmacol. Toxicol. 40, 581-616. DOI |
7 | Turgeon, D., J. S. Carrier, E. Levesque, B. G. Beatty, A. Belanger, and D. W. Hum. 2000. Isolation and characterization of the human UGT2B15 gene, localized within a cluster of UGT2B genes and pseudogenes on chromosome 4. J. Mol. Biol. 295, 489-504. DOI |
8 | Wilson, W., F. Pardo-Manuel de Villena, B. D. Lyn-Cook, P. K. Chatterjee, T. A. Bell, D. A. Detwiler, R. C. Gilmore, I. C. Valladeras, C. C. Wright, D. W. Threadgill, and D. J. Grant. 2004. Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15. Genomics 84, 707-714. DOI |
9 | Mackenzie, P. I., I. S. Owens, B. Burchell, K. W. Bock, A. Bairoch, A. Bélanger, S. Fournel-Gigleux, M. Green, D. W. Hum, T. Iyanagi, D. Lancet, P. Louisot, J. Magdalou, J. R. Chowdhury, J. K. Ritter, H. Schachter, T. R. Tephly, K. F. Tipton, and D. W. Nebert. 1997. The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics 7, 255-269. DOI |
10 | Xue, Y., D. Sun, A. Daly, F. Yang, X. Zhou, M. Zhao, N. Huang, T. Zerjal, C. Lee, N. P. Carter, M. E. Hurles, and C. Tyler-Smith. 2008. Adaptive evolution of UGT2B17 copy-number variation. Am. J. Hum. Genet. 83, 337-346. DOI |
11 | Mackenzie, P. I., K. W. Bock, B. Burchell, C. Guillemette, S. Ikushiro, T. Iyanagi, J. O. Miners, I. S. Owens, and D. W. Nebert. 2005. Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily. Pharmacogenet Genomics 15, 677-85. DOI |
12 | Chen, G., R. W. Dellinger, D. Sun, T. E. Spratt, and P. Lazarus. 2008. Glucuronidation of tobacco-specific nitrosamines by UGT2B10. Drug Metab. Dispos. 36, 824-830. DOI |
13 | Menard, V., O. Eap, M. Harvey, C. Guillemette, and E. Levesque. 2009. Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism. Hum. Mutat. 30, 1310-1319. DOI |
14 | Jemal, A., K. C. Chu, and R. E. Tarone. 2001. Recent trends in lung cancer mortality in the United States. J. Natl. Cancer Inst. 93, 277-283. DOI |
15 | Kim, Y. C., Y. S. Kwon, I. J. Oh, K. S. Kim, S. Y. Kim, J. S. Ryu, H. K. Yum, S. J. Yong, K. H. Lee, C. G. Lee, S. Y. Lee, S. Y. Lee, M. H. Jung, E. T. Jeong, and K. H. In. 2007. National survey of lung cancer in Korea, 2005. J. Lung Cancer 6, 67-73. DOI |
16 | Lazarus, P., Y. Zheng, E. A. Runkle, J. E. Muscat, and D. Wiener. 2005. Genotype-phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes. Pharmacogenet Genomics 15, 769-778. DOI |
17 | Hirsch, F. R., M. V. Garcia, F. Cappuzzo, and et al. 2007. Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small-cell lung cancer patients treated with gefitinib. Ann. Oncol. 18, 752-760. |
18 | Jakobsson, J., L. Ekstrom, N. Inotsume, M. Garle, M. Lorentzon, C. Ohlsson, H. K. Roh, K. Carlström, and A. Rane. 2006. Large differences in testosterone excretion in Korean and Swedish men are strongly associated with a UDP-glucuronosyl transferase 2B17 polymorphism. J. Clin. Endocrinol Metab. 91, 687-693. DOI |
19 | Hecht, S. S., S. G. Carmella, I. Stepanov, J. Jensen, A. Anderson, and D. K. Hatsukami. 2008. Metabolism of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to its biomarker total NNAL in smokeless tobacco users. Cancer Epidemiol Biomarkers Prev. 17, 732-735. DOI |
20 | Chakravarti, A. and A. Lynn. 2004. Meiotic mapping in human. In: Birren B., E. D. Green, S. Klapholz, R. M. Myers, Roskams (eds.), Genome analysis: A laboratory manual. Cold Spring Harber Laboratory Press, CSH, NewYork. Vol 4. |
21 | Chouinard, S., O. Barbier, and A. Bélanger. 2007. UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells. J. Biol. Chem. 282, 33466-33474. DOI |
22 | Gallagher, C. J., F. F. Kadlubar, J. E. Muscat, C. B. Ambrosone, N. P. Lang, and P. Lazarus. 2007. The UGT2B17 gene deletion polymorphism and risk of prostate cancer. A case-control study in Caucasians. Cancer Detect Prev. 31, 310-315. DOI |
23 | Bao, B. Y., B. F. Chuang, Q. Wang, O. Sartor, S. P. Balk, M. Brown, P. W. Kantoff, and G. S. Lee. 2008. Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes. Prostate 68, 839-848. DOI |
24 | Gallagher, C. J., J. E. Muscat, A. N. Hicks, Y. Zheng, A. M. Dyer, G. A. Chase, J. Richie, and P. Lazarus. 2007. The UDP-glucuronosyltransferase 2B17 gene deletion polymorphism: sex-specific association with urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronidation phenotype and risk for lung cancer. Cancer Epidemiol Biomarkers Prev. 16, 823-828. DOI |
25 | Guillemette, C. 2003. Pharmacogenomics of human UDP-glucuronosyltransferase enzymes. Pharmacogenomics J. 3, 136-158. DOI |
26 | Beaulieu, M., E. Levesque, D. W. Hum, and A. Belanger. 1996. Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids. J. Biol. Chem. 271, 22855-22862. DOI |