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http://dx.doi.org/10.5352/JLS.2010.20.2.245

The Effect of Aerobic Exercise and Allium Tuberosum Intake on Blood Lipids, MDA and Antioxidant Enzyme in Rats  

Baek, Yeong-Ho (Department of Physical Education, Busan National University)
Lee, Sang-Ho (Department of Physical Education, Busan National University)
Publication Information
Journal of Life Science / v.20, no.2, 2010 , pp. 245-252 More about this Journal
Abstract
The purpose of this study was to investigate the effects of aerobic exercise and Allium tuberosum intake on blood lipids, MDA and antioxidant enzyme in rats. Twenty four male Sprague-Dawley rats, 4 weeks old, were used. Experimental groups were aerobic exercise with Allium tuberosum intake group (A, n=6), aerobic exercise group (B, n=6), Allium tuberosum intake group (C, n=6), and the control group (D, n=6). Aerobic exercise was administered through a treadmill running program (14~15 m/min, $0^{\circ}$ grade, 25~30 min/day, 5 day/wk) and these rats were given 5% Allium tuberosum for 2 wk. The results of this study are as follows: TC and TG didn't show change; groups A, B, C showed a significant increase in HDL-C compared to the D group; groups A, B, and C showed a significant decrease in LDL-C compared to the D group; groups B and C showed a significant decrease in MDA level compared to the D group; groups B and C showed a significant increase in SOD activity compared to the D group; and the A group showed a significant increase in CAT activity compared to the D group. In conclusion, low intensity aerobic exercise and intake of the natural antioxidant Allium tuberosum seem to have the health promoting effect of retarding oxidative stress by decreasing lipid peroxidation.
Keywords
Aerobic exercise; allium tuberosum; antioxidant enzyme;
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1 Witt, E. H., A. Z. Reznick., C. A. Viguie., P. Starke-Reed, and L. Packer. 1992. Exercise, Oxidative Damage and Effects of Antioxidant Manipulation. J. Nutr. 122, 766-773.
2 Yoo, S. O. and J. H. Bae. 1993. Investigation of Korean native Chinese chives on flower bud differentiation. J. Kor. Soc. Hort Sci. 34, 395-401.
3 Park, S. Y. 2003. Effect of circulation exercise on physical fitness and blood lipid in obese children. Graduate School Sang-myung University.
4 Perez, D. D., P. Strobel, R. Foncea, M. S. Diez, L. Vasquez, I. Urquiaga, O. Castillo, A. Cuevas, A. San, Martin, and F. Leighton. 2002. Wine, diet, antioxidant defenses, and oxidative damage. Ann. N. Y. Acad. Sci. 957, 136-145.   DOI
5 Savickiene, N., A. Dagilyte., A. Lukosius, and V. Zitkevicius. 2002. Importance of biologically active compounds and plants in the prevention of diabetes mellitus. Medicina 38, 970-975.
6 Scjokman, C. P., H. Ingrid, E. Rutishauser, and R. J. Wallace. 1999. Pre and post game macronutrient intake of a group of elite Australian football players. Int. J. Sport Nutr. Exerc. Metab. 9, 60-96.
7 Sen, C. K., M. Atalay, and O. Hanninen. 1994. Exercise-induced oxidative stress: glutathione supplementation and deficiency. J. Appl. Physiol. 77, 2177-2187.
8 Sen, C. K., and O. Hanninen. 1994. Physiological antioxidants: pp. 89-126, In Exercise and Oxygen Toxicity, In Sen, C. K., L. Packer, and O. Hanninen. Amsterdam: Elsevier Science.
9 Slowing, K., P. Ganado, M. Sanz, E. Ruiz, and T. Tejerina. 2001. Study of garlic extracts and fractions on cholesterol plasma levels and vascular reactivity in cholesterol-fed rats. J. Nur. 131, 219-225.
10 Somani, S. M., S. Frank, and L. P. Rybakal. 1995. Responses of antioxidant system to acute and trained exercise in rat heart subcellular fractions. Pharmacology Biochemistry and Behavior 51, 627-634.   DOI
11 Song, S. K. 2007. Effects of Dance Sports Exercise on Health-related Fitness, Body Composition and Serum Lipids in Old-aged Women. Graduate School of Education Kyungsung University.
12 Thompson, P. D., D. Buchner, I. L. Pina, G. J. Balady, M. A. Williams. B. H. Marcus, K. Berra, S. N. Blair. and F. Costa. 2003. Exercise and physical activity in the prevention and treatment of aterosclerotic cardiovascular disease. Circulation 107, 3109-3116.   DOI
13 Lowry, O. H., N. J. Rsenbrough, and A. L. Rarr. 1997. Protein measurement with folin phenol reagent. J. Biol. Chem. 193, 265-275.
14 Maxwell, S. R. J., P. Jakeman, and H. Thomason. 1993. Change in plasma antioxidant status during eccentric exercise and the effect of vitamin supplementation. Free Rad. Res. Commum. 19, 191.   DOI
15 Mena, P., M. Maynar, J. M. Gutierrez, J. Timon, and J. E. Campillo. 1991. Erythrocyte free radical scavenger enzymes in bicycle professional racers, Adapt at into training. Int. J. Sports Med 12, 563-566.   DOI
16 Moon, G. S. and M. J. Lee. 2003. The long term effect of Buchu (Chinese chives) diet on ROS formation in the liver and skin tissue of ICR mice. Journal of the Korean Society of Food Science and Nutrition 32, 444-449.   과학기술학회마을   DOI
17 Niess, A. M., H. H. Dickhuth, H. Northoff, and E. Fehrenbach. 1999. Free radicals and oxidative stress in exercise immunological aspects. Exercise Immunology Review 5, 22-56.
18 Niesse, A. M., A. Harmann, M. Grunert-Fuchs, B. Poch, and G. Speit. 1996. DNA damage after exhaustive treadmill running in trained and untrained men. International J. Sport Med. 17, 397-403.   DOI
19 Overton, P. D., N. Fuurlonger, J. M. Beety., J. Chakraborty, J. A. Tredger, and L. M. Morgan. 1994. The effects of dietary sugar-beet fiber and guar on lipid metabolism in Wistar rats. Br. J. Nutr. 72, 385-395.   DOI
20 Ohno, H., H. Yamachita, T. Ookawara, D. Saitoh, K. Wakabayashi, and N. Taniquchi. 1992. Training effects on concentration of immuno reactive superoxide dismutase iso-enzymes in human plasma. Acta Physiology 167, 301-303.
21 Park, J. Y., M. J. Kim, Y. K. Kim, Y. S. Jin, and H. J. Lee. 1999. The effect of exercise pattern and antioxidant Supplement on antioxidant enzymes and total antioxidant status. The Korean Journal of Physical Education 38, 451-460.
22 Jung, H. S., K. H. Noh, H. Y. Cho, J. Y. Park, C. Y. Choi, T. W. Kwon, and Y. S. Song. 2003. Effect of buchu (Allium tuberosum) on lipid peroxidation and antioxidative defense system in streptozotocin-induced diabetic rats. Journal of Life Science 13, 333-342.   DOI
23 Katzmarzyk, P. T., A. S. Leon., T. Rankinen., J. Gagnon., J. S. Skinner., J. H. Wilmore., D. C. Rao, and C. Bouchard. 2001. Changes in blood lipids consequent to aerobic exercise training related to changes in body fatness and aerobic fitness. Metabolism. Jul 50, 841-848.   DOI
24 Kim, M. Y., S. W. Choi, and S. K. Chung. 2000. Antioxidative Flavonoids from the Garlic (Allium sativum L.) Shoot. Food Science and Biotechnology 9, 199-203.
25 Kim, B. R. and J. P. Park. 2003. The effects of bare feet walking on the body composition and blood lipid profiles of obese female-students in the middle school. The Korean Journal of Physical Education 12, 517-528.
26 Kumari, M., J. S. Yudkin, S. E. Humphries, V. Mohamed-Ali. Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link? 1999. Atherosclerosis 148, 209-214.
27 Leeuwenburgh, C., J. Hollander, S. Leichtweis, M. Griffiths, and L. L. Ji. 1997. Adaptation of glutathione antioxidant system to endurance training are tissue and muscle fiber-specific. American Journal of Physiology 272, 363-369.
28 Kwon, T. D., S. P. Ryu, W. C. Jang. and S. C. Lee. 2002. Effects of Green Tea Polyphenol Ingestion on Blood Lipids, MDA and SOD in Rats. The Korean Journal of Exercise Nutrition 6, 85-88.
29 Lee, G. P. and I. S. Lim. 2000. The Changes of MDA, SOD, and Catalase by Overtraining. The Korean Journal of Physical Education 39, 426-435.
30 Lee, M. J., B. M. Ryu, Y. S. Lee, and G. S. Moon. 2002. Effect of Long Term Buchu (Chinese chives) Diet on Antioxidative System of ICR Mice. Korean Society of Food Science and Technology 31, 834-839.   과학기술학회마을   DOI
31 Gluohua, C. and Chen. Jidi. 1991. Effects of dietary zinc on free radical generation, lipid peroxidation, and superoxide dismutase in trained mice. Archives of Biochemisstry and Biophysics 291, 147-153.   DOI
32 Goldberg, L., D. L. Elliot, R. W. Schultz, and F. E. Kloster. 1984. Changers in lipid and lipoprotein levels after weight training. Journal of the American Medical Association 252, 504-506.   DOI
33 Goldfarb, A. and C. K. Sen. 1994. Antioxidant supplementation and the control of oxygen toxicity during exercise. Exercise and Oxygen Toxicity. pp. 163-189, In Sen, C. K., L. Packer, and O. Hanninen (eds.), Amsterdam: Elsevier Science.
34 Guie, C. A., B. Frei, and M. K. Shigenaga. 1993. Antioxidant status and indexes of oxidative stress during consecutive days of exercise. J. Appl. Physiol. 75, 566.
35 Halliwell, B. 1991. Reactive oxygen species in living system. Sourcs, biochemistry and role in human disease. The American Journal of Medicine 91, 14-22.
36 Ji, L. L. 1999. Antioxidants and Oxidative Stress in Exercise. P.S.E.B.M. 222, 283-292.
37 Jeong, D. J. 1999. The Effect of antioxidants supplementation and exercise intensity on the lipid peroxidation and the activities of antioxidative enzymes. PhD Dissertation. Seoul National University.
38 Ji, L. L. 1993. Antioxidant enzyme response to exercise and aging. Med. Sci. Sports Exerc. 25, 225-231.
39 Ji, L. L. 1995. Exercise and oxidative stress: role of the cellular antioxidant systems. Exercise Sports Science Review, 23, 135-166.
40 Jeon, J. K., B. W. Jeong, S. K. Lee, H. G. Park, H. Y. Jang, and W. R. Lee. 2006. Effects of long-term endurance exercise training and L-arginine supplementation on superoxide production and antioxidants enzyme protein expression of Aorta in spontaneously hypertensive rat. Korean Academy Society of Exercise Nutrition 10, 331-340.
41 Ahn, Y. J. 1998. Effects of Caloric Restriction and Training Regimens on Body Composition, Serum Lipids, and Muscle Strength. PhD Dissertation. Korea National Sport University.
42 Alessio, H. M. 1993. Exercise induced-oxidative stress. Med. Sci. Sports Exercise 25, 218-224.
43 Durstine, J. L., P. W. Grandjean, C. A. Cox, and P. D. Thompson. 2002. Lipids, lipoproteins, and exercise. Journal of Cardiopulmonary Rehabilitation and Prevention 22, 385-398.   DOI
44 Anatol, K., M. Ulrike, A. Sonke, U. Amaar, L. Charotrharlotte, M. T. Tom, and B. Ulrike. 2001. Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease. Free Rad. Biol. Med. 31, 1570-1581.   DOI
45 Bedford, T. G., C. M. Tipton, N. C. Wilson, R. A. Oppliger, and C. V. Gisolfi. 1979. Maximum oxygen consumption of rats and its changes with various experimental procedures. Journal of Applied Physiology 47, 1278-1283.
46 Bounous, G., S. Sukkar, and J. H. Molson. 2003. The Antioxidant System. Anticancer Research 23, 1411-1416.
47 Friedwald, W. T., R. I. Levy, and D. S. Fredrickson. 1972. Estimation of concen-tration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin. Chem. 18, 499-502.