Browse > Article
http://dx.doi.org/10.5352/JLS.2010.20.11.1603

Effect of Fucus evanescens Fucoidan on Expression of Matrix Metalloproteinase-1 Promoter, mRNA, Protein and Signal Pathway  

Ku, Mi-Jeong (Institute of Natural Products for Health Promotion and Department of Preventive Medicine, College of Medicine, Kosin University)
Jung, Ji-Won (Institute of Natural Products for Health Promotion and Department of Preventive Medicine, College of Medicine, Kosin University)
Lee, Myeong-Sook (Institute of Natural Products for Health Promotion and Department of Preventive Medicine, College of Medicine, Kosin University)
Cho, Byung-Kyu (Institute of Natural Products for Health Promotion and Department of Preventive Medicine, College of Medicine, Kosin University)
Lee, Soon-Rye (Department of Beauty Art, Institute for Continuing Education, Youngsan University)
Lee, Hye-Sook (Department of Beauty and Health Care, Daejeon University)
Vischuk, Olesya S. (Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of the Russian Academy of Sciences)
Zvyagintseva, Tatyana N. (Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of the Russian Academy of Sciences)
Ermakova, Svetlana P. (Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of the Russian Academy of Sciences)
Lee, Yong-Hwan (Institute of Natural Products for Health Promotion and Department of Preventive Medicine, College of Medicine, Kosin University)
Publication Information
Journal of Life Science / v.20, no.11, 2010 , pp. 1603-1610 More about this Journal
Abstract
Fucoidans are sulfated fucosylated polymers from the cell wall of brown algae. We assessed the effects of Fucus evanescens fucoidan on ultraviolet-B (UVB)-induced expression of matrix metalloproteinase-1 (MMP-1) protein, mRNA, and promoter, and the phosphorylation of mitogen-activated protein kinases in vitro using an immortalized human keratinocyte cell line. Pretreatment with 10 and $100\;{\mu}g/ml$ fucoidan significantly inhibited UVB-induced MMP-1 protein, mRNA and promoter activity, compared to UVB irradiation alone. Extracellular signal regulated kinase activation was markedly inhibited by treatment with fucoidan, though c-JUN N-terminal kinase activity and p38 activation were only marginally affected by fucoidan. F. evanescens fucoidan may be a potential therapeutic agent for the prevention and treatment of skin photoaging.
Keywords
Matrix metalloproteinase-1; fucoidan; ultraviolet B; photoaging; skin;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
2 McLellan, D. S. and K. M. Jurd. 1992. Anticoagulants from marine algae. Blood Coagul. Fibrinolysis 3, 69-77.   DOI
3 Moon, H. I., M. R. Kim, E. R. Woo, and J. H. Chung. 2005. Triterpenoid from Styrax japonica SIEB. et ZUCC, and its effects on the expression of matrix metalloproteinases-1 and type 1 procollagen caused by ultraviolet irradiated cultured primary human skin fibroblasts. Biol. Pharm. Bull. 28, 2003-2006.   DOI
4 Moon, H. J., S. R. Lee, S. N. Shim, S. H. Jeong, V. A. Stonik, V. A. Rasskazov, T. Zvyagintseva, and Y. H. Lee. 2008. Fucoidan inhibits UVB-induced MMP-1 expression in human skin fibroblasts. Biol. Pharm. Bull. 31, 284-289.   DOI
5 DuBois, M., K. Gilles, J. Hamilton, P. Roberts, and F. Smith. 1956. Colorimetric method for determination of sugars and related substances. Anal. Chem. 28, 350-356.   DOI
6 Fisher, G. J., S. C. Datta, H. S. Talwar, Z. Q. Wang, J. Varani, S. Kang, and J. J. Voorhees. 1996. Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature 379, 335-339.   DOI
7 Fisher, G. J., Z. Q. Wang, S. C. Datta, J. Varani, S. Kang, and J. J. Voorhees. 1997. Pathophysiology of premature skin aging induced by ultraviolet light. N. Engl. J. Med. 337, 1419-1428.   DOI
8 Fisher, G. J., H. S. Talwar, J. Lin, P. Lin, F. McPhillips, Z. Wang, X. Li, Y. Wan, S. Kang, and J. J. Voorhees. 1998. Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo. J. Clin. Invest. 101, 1432-1440.   DOI
9 Ho, J. N., Y. H. Lee, Y. D. Lee, W. J. Jun, H. K. Kim, B. S. Hong, D. H. Shin, and H. Y. Cho. 2005. Inhibitory effect of Aucubin isolated from Eucommia ulmoides against UVB-induced matrix metalloproteinase-1 production in human skin fibroblasts. Biosci. Biotechnol. Biochem. 69, 2227-2231.   DOI
10 Jenkins, G. 2002. Molecular mechanisms of skin ageing. Mech. Ageing Dev. 123, 801-810.   DOI
11 Alekseyenko, T. V., S. Y. Zhanayeva, A. A. Venediktova, T. N. Zvyagintseva, T. A. Kuznetsova, N. N. Besednova, and T. A. Korolenko. 2007. Antitumor and antimetastatic activity of fucoidan, a sulfated polysaccharide isolated from the Okhotsk Sea Fucus evanescens brown alga. Bull. Exp. Biol. Med. 143, 730-732.   DOI
12 Joe, M. J., S. U. Kim, H. Y. Choi, W. S. Shin, G. M. Park, D. W. Kang, and Y. K. Kim. 2006. The inhibitory effects of eckol and dieckol from Ecklonia stolonifera on the expression of matrix metalloproteinase-1 in human dermal fibroblasts. Biol. Pharm. Bull. 29, 1735-1739.   DOI
13 Zvyagintseva, T. N., N. M. Shevchenko, E. L. Nazarenko, V. I. Gorbach, A. M. Urvantseva, M. I. Kiseleva, and V. V. Isakov. 2005. Water-soluble polysaccharides of some brown algae of the Russian Far-East. Structure and biological action of low-molecular mass polyuronans. J. Exp. Mar. Biol Ecol. 320, 123-131.   DOI
14 Murphy, K. A., C. M. Villano, R. Dorn, and L. A. White. 2004. Interaction between the aryl hydrocarbon receptor and retinoic acid pathways increases matrix metalloproteinase-1 expression in keratinocytes. J. Biol. Chem. 279, 25284-25293.   DOI
15 Quan, T., T. He, S. Kang, J. J. Voorhees, and G. J. Fisher. 2004. Solar ultraviolet irradiation reduces collagen in photoaged human skin by blocking transforming growth factor-beta type II receptor/Smad signaling. Am. J. Pathol. 165, 741-751.   DOI
16 Senni, K., F. Gueniche, A. Foucault-Bertaud, S. Igondjo-Tchen, F. Fioretti, S. Colliec-Jouault, P. Durand, J. Guezennec, G. Godeau, and D. Letourneur. 2006. Fucoidan a sulfated polysaccharide from brown algae is a potent modulator of connective tissue proteolysis. Arch. Biochem. Biophys. 445, 56-64.   DOI
17 Sun, Y., Y. Sun, L. Wenger, J. L. Rutter, C. E. Brinckerhoff, and H. S. Cheung. 1999. p53 down-regulates human matrix metalloproteinase-1 (Collagenase-1) gene expression. J. Biol. Chem. 274, 11535-11540.   DOI
18 Kim, H. H., C. M. Shin, C. H. Park, K. H. Kim, K. H. Cho, H. C. Eun, and J. H. Chung. 2005. Eicosapentaenoic acid inhibits UV-induced MMP-1 expression in human dermal fibroblasts. J. Lipid Res. 46, 1712-1720.   DOI
19 Kusaykin, M. I., A. O. Chizhov, A. A. Grachev, S. A. Alekseeva, I. Y. Bakunina, O. I. Nedashkovskaya, V. V. Sova, and T. N. Zvyagintseva. 2006. A comparative study of specificity of fucoidanases from marine microorganisms and invertebrates. J. Appl. Phycol. 18, 369-373.   DOI
20 Anastyuk, S. D., N. M. Shevchenko, E. L. Nazarenko, P. S. Dmitrenok, and T. N. Zvyagintseva. 2009. Structural analysis of a fucoidan from the brown alga Fucus evanescens by MALDI-TOF and tandem ESI mass spectrometry. Carbohydr. Res. 344, 779-787.   DOI
21 Benbow, U. and C. E. Brinckerhoff. 1997. The AP-1 site and MMP gene regulation: what is all the fuss about? Matrix Biol. 15, 519-526.   DOI
22 Bilan, M. I., A. A. Grachev, N. E. Ustuzhanina, A. S. Shashkov, N. E. Nifantiev, and A. I. Usov. 2002. Structure of a fucoidan from the brown seaweed Fucus evanescens C. Ag. Carbohydr. Res. 337, 719-730.   DOI
23 Boukamp, P., R. T. Dzarlieva-Petrusevska, D. Breitkreuz, J. Hornung, A. Markham, and N. E. Fuseing. 1988. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Biol. Chem. 106, 761-771.
24 Chomczynski, P. and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
25 Chung, J. H., J. Y. Seo, M. K. Lee, H. C. Eun, J. H. Lee, S. Kang, G. J. Fisher, and J. J. Voorhees. 2002. Ultraviolet modulation of human macrophage metalloelastase in human skin in vivo. J. Invest. Dermatol. 119, 507-512.   DOI
26 Makarenkova, I. D., G. G. Kompanets, N. N. Besednova, R. A. Slonova, T. N. Zviagintseva, and N. M. Shevchenko. 2008. Inhibiting effects of fucoidans on Hantaan virus adsorption on a model of peritoneal macrophages in vitro. Vopr. Virusol. 53, 12-15. (Russian).
27 Kuznetsova, T. A., N. N. Besednova, A. N. Mamaev, A. P. Momot, N. M. Shevchenko, and T. N. Zvyagintseva. 2003. Anticoagulant activity of fucoidan from brown algae Fucus evanescens of the Okhotsk Sea. Bull. Exp. Biol. Med. 136, 471-473.   DOI
28 Kylin, H. 1913. Zur Biochemie der Meeresalgen. Z. Physiol. Chemie. 83, 171-197.   DOI
29 Lapikova, E. S., N. N. Drozd, A. S. Tolstenkov, V. A. Makarov, T. N. Zvyagintseva, N. M. Shevchenko, I. U. Bakunina, N. N. Besednova, and T. A. Kuznetsova. 2008. Inhibition of thrombin and factor Xa by Fucus evanescens fucoidan and its modified analogs. Bull. Exp. Biol. Med. 146, 328-333.   DOI
30 Li, B., F. Lu, X. Wei, and R. Zhao. 2008. Fucoidan: structure and bioactivity. Molecules 13, 1671-1695.   DOI
31 Lim, H. and H. P. Kim. 2007. Inhibition of mammalian collagenase, matrix metalloproteinase-1, by naturally-occurring flavonoids. Planta Med. 73, 1267-1274.   DOI
32 Cumashi, A., N. A. Ushakova, M. E. Preobrazhenskaya, A. D'Incecco, A. Piccoli, L. Totani, N. Tinari, G. E. Morozevich, A. E. Berman, M. I. Bilan, A. I. Usov, N. E. Ustyuzhanina, A. A. Grachev, C. J. Sanderson, M. Kelly, G. A. Rabinovich, S. Iacobelli, and N. E. Nifantiev. 2007. A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds. Glycobiology 17, 541-552.
33 Dodgson, K. S. and R. G. Price. 1962. A note on the determination of the ester sulfate content of sulfated polysaccharides. Biochem. J. 84, 106-110.