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http://dx.doi.org/10.5352/JLS.2009.19.2.213

Effects of Relative Swimming Exercise Intensity on mRNA Expression of UCP-1, UCP-3 Brown Adipose Tissue and Blood Insulin, and Glucose in Rat  

Yoon, Jin-Hwan (Department of Sports Science, Hannam University)
Oh, Myung-Jin (Department of Sports Science, Hannam University)
Seo, Tae-Beom (Department of Sports Science, Hannam University)
Kim, Jong-Oh (Department of Sports Science, Hannam University)
Jang, Moon-Nyeo (Department of Sports Science, Hannam University)
Park, Seong-Tae (Department of Sports Science, Hannam University)
Kim, Young-Pyo (Department of Physical Education, Cheju University)
Yoo, Jae-Hyun (Division of Social Welfare, Sahmyook University)
Publication Information
Journal of Life Science / v.19, no.2, 2009 , pp. 213-218 More about this Journal
Abstract
The purpose of this study was to investigate the UCP-1, UCP-3 mRNA expression in brown adipose tissue with glycometabolism according to intensity and duration of swimming in rat. F344 rat were randomly divided into three groups (n=10 in each group): control (CON), low-intensity swimming (LIS) groups, and high-intensity swimming (HIS) groups. Animals in the LIS group were forced to swim in swimming pool for 30min once a day for 8 consecutive weeks with a light intensity. In the HIS group, the rats repeated fifteen 20-s swimming bouts with a weight equivalent to 10% of body weight for 8weeks, respectively. The present result demonstrated that in LIS group, serum insulin and glucose levels significantly decreased in LIS group compared to CON. Brown adipose tissue UCP-1 and UCP-3mRNA expression was significantly increase in LIS group compared to CON and HIS groups. From those results, it can be suggested that low-intensity swimming may improve glycometablism control by up-regulating UCP-1 and UCP-3mRNA expression.
Keywords
Swimming exercise; F344 rat; UCP mRNA; adipose tissue; blood insulin;
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