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http://dx.doi.org/10.5352/JLS.2008.18.9.1225

Potential Allelic Association of Microsatellite Markers on Bovine Chromosome 5 with Carcass Traits in Hanwoo (Korean cattle)  

Oh, Jae-Don (Genomic Informatics Center, Hankyong National University)
Kong, Hong-Sik (Genomic Informatics Center, Hankyong National University)
Cho, Byung-Wook (School of Bio-Resources and PNU-special Animal Biotechnology Center, Pusan National University)
Lee, Mi-Rang (School of Bio-Resources and PNU-special Animal Biotechnology Center, Pusan National University)
Jeon, Gwang-Joo (Genomic Informatics Center, Hankyong National University)
Lee, Hak-Kyo (Genomic Informatics Center, Hankyong National University)
Publication Information
Journal of Life Science / v.18, no.9, 2008 , pp. 1225-1229 More about this Journal
Abstract
A total of 10 polymorphic microsatellite markers on bovine chromosome 5 were used for allelic association tests with phenotypic characteristics in Hanwoo. The data analyzed in this study were collected from 326 steers. Chi-square tests were performed to compare the frequencies of individual alleles between the high and the low breeding value groups. The following breeding values were analyzed for QTL effects. The frequency of allele 239 of DIK2828 showed a significant difference between the high and the low breeding value groups in the breeding value of marbling score (MSBV). The allele 279 of BMC1009 was found to show significant differences in allelic distribution for the breeding value of cold carcass weight (CWBV) and the breeding value of backfat thickness (BFBV) and allele 285 showed significant differences in allelic distribution for CWBV, BFBV, and MSBV. The allele 200 of DIK4329 showed significant differences in allelic distributions for the breeding values of longissimus muscle area (LMABV) and BFBV. In this study, we identified the QTL for carcass traits at around 20 (DIK2828), 41 (BMC1009) and 95 (DIK4329) cM in chromosome 5. The results provided a useful reference for further positional candidate gene research and marker-assisted selection for fat metabolism and carcass traits.
Keywords
QTL; microsatellite; allelic association; chromosome 5; carcass traits; Hanwoo;
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