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http://dx.doi.org/10.5352/JLS.2008.18.6.770

Investigation of Single Nucleotide Polymorphisms in Porcine Candidate Genes for Economic Traits in the Commercial Pig Breed  

Kim, Sang-Wook (Department of Animal Science & PNU - Special Animal Biotechnology Center, Pusan National University)
Lee, Mi-Rang (Department of Animal Science & PNU - Special Animal Biotechnology Center, Pusan National University)
Kang, Han-Seok (Department of Animal Science & PNU - Special Animal Biotechnology Center, Pusan National University)
Kim, Seon-Ku (Department of Animal Science & PNU - Special Animal Biotechnology Center, Pusan National University)
Shin, Teak-Soon (Department of Animal Science & PNU - Special Animal Biotechnology Center, Pusan National University)
Lee, Hong-Gu (Department of Animal Science & PNU - Special Animal Biotechnology Center, Pusan National University)
Jeon, Hae-Yeal (Department of Animal Science & PNU - Special Animal Biotechnology Center, Pusan National University)
Kim, Kwan-Suk (Department of Animal Science, Chungbuk National University)
Do, Chang-Hee (Division of Animal Science and Technology, Chungnam National University)
Choi, Bong-Hwan (International Technical Cooperation Center, Rural Development Administration, RDA)
Kim, Tae-Hun (International Technical Cooperation Center, Rural Development Administration, RDA)
Cho, Byung-Wook (Department of Animal Science & PNU - Special Animal Biotechnology Center, Pusan National University)
Publication Information
Journal of Life Science / v.18, no.6, 2008 , pp. 770-775 More about this Journal
Abstract
Several studies reported quantitative trait loci (QTL) for meat quality on porcine chromosome 2. For application of the chromosomal information to pig industry through using DNA technology, single nucleotide polymorphism (SNP) markers are developed by comparative re-sequencing of polymerase chain reaction (PCR) products of 13 candidate genes. A total of 34 SNPs were identified in 11 PCR products, an average of one SNP in every 296 bp.PCR restriction fragment length polymorphism (RFLP) assays were developed for 11 SNPs and used to genotype four commercial pig populations in Korea. The SNP markers were used to map candidate genes in QTL and to clarify the relevance of SNP and quantitative traits.
Keywords
Economic traits; pig candidate gene; single nucleotide polymorphism; quantitative trait loci; commercial pig breed;
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