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http://dx.doi.org/10.5352/JLS.2008.18.4.509

Effects of Mole Crickets (Gryllotalpa orientalis) Extracts on Anti-oxidant and Anti-inflammatory Activities.  

Heo, Jin-Chul (Food and Bio-Industry Research Institute, Kyungpook National University)
Lee, Dong-Yeob (Department of Life & Food Science, Kyungpook National University)
Son, Min-Sik (Department of Life & Food Science, Kyungpook National University)
Yun, Chi-Young (Department of Biology, Daejeon University)
Hwang, Jae-Sam (National Institute of Agricultural Science & Technology, RDA)
Kang, Seok-Woo (National Institute of Agricultural Science & Technology, RDA)
Kim, Tae-Ho (Department of Medicine, Kyungpook National University School of Medicine)
Lee, Sang-Han (Food and Bio-Industry Research Institute, Kyungpook National University, Department of Life & Food Science, Kyungpook National University)
Publication Information
Journal of Life Science / v.18, no.4, 2008 , pp. 509-514 More about this Journal
Abstract
Tremendous natural product extracts were used as a herb medicine remedy or therapy for centuries. Because these extracts have various biological activities, we examined the effects of Gryllotalpa orientalis extract for anti-oxidant and anti-inflammation activity by 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing ability of plasma (FRAP), hydroxy radical scarvenging and cyclooxygenase-2 promoter assays. Gryllotalpa orientalis extracts were prepared from solvents such as distilled water (DW), dimethyl sulfoxide (DMSO), ethanol and methanol. The results showed that Gryllotalpa orientalis extracts have potent DPPH (methanol extract), FRAP (DW extract) and hydroxy radical scavenging (DW and methanol extracts) activity than any other extracts used. A significant inhibition of cyclooxygenase-2 (Cox-2) promoter activity was detected in the presence of DMSO extract or ethanol extract. Collectively, the present results suggested that Gryllotalpa orientalis extract could be used for anti-oxidant and/or anti-inflammation agent for human or agricultural purposes.
Keywords
Gryllotalpa orientalis; anti-oxidant; anti-inflammation; cyclooxygenase-2;
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