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http://dx.doi.org/10.5352/JLS.2007.17.8.1147

The Evaluation of Anti-wrinkle Effects in Oriental Herb Extract  

Kang, Kum-Suk (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University)
Kim, In-Deok (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University)
Kwon, Ryun-Hee (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University)
Heo, Ye-Young (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University)
Oh, Sang-Hoon (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University)
Kim, Min-Ah (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University)
Jung, Hye-Jin (Amaranth Cosmetics)
Kang, Hwan-Yul (Amaranth Cosmetics)
Ha, Bae-Jin (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University)
Publication Information
Journal of Life Science / v.17, no.8, 2007 , pp. 1147-1151 More about this Journal
Abstract
The human skin is constantly exposed to environmental irritants such as ultraviolet, smoke and chemicals. Free radicals and reactive oxygen species caused by them play critical roles in cellular damage. They not only injure the skin structure but also participate in the immensely complex inflammatory reaction. Anti-wrinkle effects of the Oriental herb extracts(OHE) were evaluated by the determination of anti-oxidation, collagenase inhibition and collagen synthesis in normal human fibroblast. OHE showed antioxidative activity as high as vitamin C, trolox and DL-penicillamine. Also OHE showed promotive effect on collagen synthesis and inhibitory effect on collagenase activity. These results demonstrated that OHE could be useful as an anti-wrinkle cosmetic ingredient.
Keywords
Oriental Herb; anti-wrinkle; anti-oxidation; collagen synthesis;
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Times Cited By KSCI : 4  (Citation Analysis)
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