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http://dx.doi.org/10.5352/JLS.2007.17.6.798

Optimal Culture Conditions on the Tyrosinase Inhibitor Production by Actinomycetes F-97  

Bang, Byung-Ho (Division of Food Science, Eulji Univesity)
Rhee, Moon-Soo (Korea Research Institute of Bioscience and Biotechnology)
Kim, Jin-O (Department of Microbial Engineering, Konkuk University)
Yi, Dong-Heui (Department of Microbial Engineering, Konkuk University)
Publication Information
Journal of Life Science / v.17, no.6, 2007 , pp. 798-804 More about this Journal
Abstract
A Actinomycetes F-97 producing tyrosinase inhibitor was isolated from soil samples. The optimum culture condition for 쇼rosinase inhibitor production was investigated and the results were as follows. The best carbon source for tyrosinase inhibitor production was shown as soluble starch, the optimum concentration was 3.0%. The best nitrogen source for tyrosinase inhibitor production was shown as peptone, the optimum concentration was 0.36%. As effect of metal ions on the production of tyrosinase inhibitor, K$_2$HPO$_4$ was shown the best and the optimum concentration was 0.1 mM. The optimum pH and temperature was shown 7.0 and 30${\circ}$C, respectively. And the highest tyrosinase inhibitor production was observed at 70hr cultivation under optimum conditions in jar fermentor scale.
Keywords
Melanin; Tyrosinase; Tyrosinase inhibitor; Actinomycetes;
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