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http://dx.doi.org/10.5352/JLS.2007.17.12.1622

Investigation of Single Nucleotide Polymorphisms in Porcine Candidate Gene for Growth and Meat Quality Traits in the Berkshire Breed  

Kim, Sang-Wook (Department of Animal Science, Pusan National University)
Jung, Ji-Hye (Department of Animal Science, Pusan National University)
Do, Kyung-Tag (Department of Animal Science, Chungbuk National University)
Kim, Kwan-Suk (Department of Animal Science, Chungbuk National University)
Do, Chang-Hee (Department of Animal Science, Chungnam National University)
Park, Jun-Kyu (Livestock Veterinary Research Institute)
Joo, Young-Kuk (Livestock Veterinary Research Institute)
Kim, Tae-Suk (Livestock Veterinary Research Institute)
Choi, Bong-Hwan (Animal Genomics and Bioinformatics Division, National Livestock Research Institute)
Kim, Tae-Hun (International Technical Cooperation Center, Rural Development Administration)
Song, Ki-Duk (NICHD/National Institutes of Health)
Cho, Byung-Wook (Department of Animal Science, Pusan National University)
Publication Information
Journal of Life Science / v.17, no.12, 2007 , pp. 1622-1626 More about this Journal
Abstract
This study was conducted to identify useful single nucleotide polymorphisms (SNPs) and determine their association with economically important traits in pig population. Four candidate gene analyses have identified important chromosomal regions and major genes associcated whit economic traits of the pig. For application of the chromosomal information to the pig industry using DNA technology, SNP markers were developed by comparative re-sequencing of polymerase chain reaction (PCR) products of 4 candidate genes (CSF2, IL4, MYOD, RIP140). PCR restriction fragment length polymorphism (PCR-RFLP) assays were developed for these 4 SNPs and used to genotype Berkshire pig populations in Korea.
Keywords
Meat Quality; berkshire; PCR-RFLP; single nucleotide polymorphism; growth factor;
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1 Jungerius, B. J., A. P. Rattink, R. P. Crooijmans, J. J. Poel, B. A. Oost, M. F. Pas and M. A. Groenen. 2003. Development of a single nucleotide polymorphism map of porcine chromosome 2. Anim. Genet. 34, 429-437   DOI   ScienceOn
2 Kim, T. H., K. S. Kim, B. H. Choi, D. H. Yoon, G. W. Jang, K. T. Lee, H. Y. Chung, H. Y. Lee, H. S. Park and J. W. Lee. 2005. Genetic structure of pig breeds from Korea and China using microsatellite loci analysis. J. Anim. Sci. 83, 2255-2263   DOI
3 Van, W. H. J., B. Dibbits, E. E. Baron, A. D. Brings, B. Harlizius, M. A. Groenen, E. F. Knol and H. Bovenhuis. 2006. Identification of quantitative trait loci for carcass composition and pork quality traits in a commercial finishing cross. J. Anim. Sci. 84, 789-799   DOI
4 Wimmers, K., I. Fiedler, T. Hardge, E. Murani, K. Schellander and S. Ponsuksili. 2006. QTL for microstructural and biophysical muscle properties and body composition in pigs. BMC Genet. 9, 7-15
5 Fahrenkrug, S. C., T. P. L. Smith, G. A. Rohrer and J. W. Keele. 2002. Single nucleotide polymorphism (SNP) discovery in porcine expressed genes. Animal Genetics 33, 186-195   DOI   ScienceOn
6 Van, D. S. H., G. F. W. Prall and G. S. Plastow. 2005. Application of genomics in the pork industry. Journal of Animal Science 83, E1-E8   DOI
7 Meyers, S. N., M. B. Rogatcheva, D. M. Larkin, M. Yerle, D. Milan, R. J. Hawken, L. B. Schook and J. E. Beever. 2005. Piggy-BACing the human genome II. A high-resolution, physically anchored, comparative map of the porcine autosomes. Genomics 86, 739-752   DOI   ScienceOn
8 Fujii, J., K. Otsu, F. Zorzato, L. S. de, V. K. Khanna, J. E. Weiler, P. J. O'Brien and D. H. MacLennan. 1991. Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia. Science 253, 448-451   DOI
9 Kim, J. J., M. F. Rothschild, J. Beever, S. Rodriguez-Zas and J. C. Dekkers. 2005. Joint analysis of two breed cross populations in pigs to improve detection and characterization of quantitative trait loci. J. Anim. Sci. 83, 1229-1240   DOI
10 Kollers, S., K. Megy and D. Rocha. 2005. Analysis of public single nucleotide polymorphisms in commercial pig populations. Animal Genetics 36, 426-431   DOI   ScienceOn
11 Malek, M., J. C. Dekkers, H. K. Lee, T. J. Baas, K. Prusa, E. Huff-Lonergan and M. F. Rothschild. 2001, A molecular genome scan analysis to identify chromosomal regions influencing economic traits in the pig. II. Meat and muscle composition. Mamm. Genome 12, 637-645   DOI   ScienceOn
12 Le, R. P., J. Naveau, J. M. Elsen and P. Sellier. 1990. Evidence for a new major gene influencing meat quality in pigs. Genet. Res. 55, 33-40   DOI   ScienceOn
13 Park, K. G., K. S. Park, M. J. Kim, H. S. Kim, Y. S. Suh, J. D. Ahn, K. K. Park, Y. C. Chang and I. K. Lee. 2004. Relationship between serum adiponectin and leptin concentrations and body fat distribution. Diabetes Res. Clin. Pract. 63, 135-142   DOI   ScienceOn