Expression of Human SOD1 and Mutant SOD1 (G93A) in E. coli and Identification of SOD1 as a Substrate of HtrA2 Serine Protease |
Kim, Goo-Young
(Department of Biomedical Sciences,Research Institute of Molecular Genetics, College of Medicine, the Catholic University of Korea)
Kim, Sang-Soo (Department of Biomedical Sciences,Research Institute of Molecular Genetics, College of Medicine, the Catholic University of Korea) Park, Hyo-Jin (Research Institute of Molecular Genetics, College of Medicine, the Catholic University of Korea,School of Life Science and Biotechnology, Korea University) Rhim, Hyang-Shuk (Department of Biomedical Sciences,Research Institute of Molecular Genetics, College of Medicine, the Catholic University of Korea) |
1 | Noor R., S. Mittal, J. Iqbal. 2002. Superoxide dismutase- applications and relevance to human diseases. Med Sci Monit. 8, 210-5 |
2 | Andersen J. K. 2004. Oxidative stress in neurodegeneration: cause or consequence? Nat Med. 10, Suppl:S18-25 DOI ScienceOn |
3 | Cilenti L., M. M. Soundarapandian, G. A. Kyriazis, V. Stratico, S. Singh, S. Gupta, J. V. Bonventre, E. S. Alnemri, A. S. Zervos. 2004. Regulation of HAX-1 anti- apoptotic protein by Omi/HtrA2 protease during cell death. J Biol Chem. 279, 50295-301 DOI ScienceOn |
4 | Dal Canto M. C., M. E. Gurney . 1995. Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS). Brain Res. 676, 25-40 DOI ScienceOn |
5 | Martins L. M., A. Morrison, K. Klupsch, V. Fedele, N. Moisoi, P. Teismann, A. Abuin, E. Grau, M. Geppert, G. P. Livi, C. L. Creasy, A. Martin, I. Hargreaves, S. J. Heales, H. Okada, S. Brandner, J. B. Schulz, T. Mak, J. Downward. 2004. Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice. Mol Cell Biol. 24, 9848-62 DOI ScienceOn |
6 | Pasinelli P., M. E. Belford, N. Lennon, B. J. Bacskai, B. T. Hyman, D. Trotti , R. H. Jr. Brown. 2004. Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria. Neuron. 43, 19-30 DOI ScienceOn |
7 | Selverstone Valentine J., P. A. Doucette, S. Zittin Potter. 2005. Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis. Annu Rev Biochem. 74, 563-93 DOI ScienceOn |
8 | Sekine K, Y. Hao, Y. Suzuki, R. Takahashi, T. Tsuruo, M. Naito. 2005. HtrA2 cleaves Apollon and induces cell death by IAP-binding motif in Apollon-deficient cells. Biochem Biophys Res Commun. 330, 279-85 DOI ScienceOn |
9 | Dawson V. L. 2004. Maiming mitochondria in familial ALS. Nat Med. 10, 905-6 DOI ScienceOn |
10 | Maier C. M., P. H. Chan. 2002. Role of superoxide dismutases in oxidative damage and neurodegenerative disorders. Neuroscientist. 8, 323-34 DOI ScienceOn |
11 | Suzuki Y., Y. Imai, H. Nakayama, K. Takahashi, K. Takio, R. Takahashi. 2001. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell. 8, 613-21 DOI ScienceOn |
12 | Verhagen A. M., J. Silke, P. G. Ekert, M. Pakusch, H. Kaufmann, L. M. Connolly, C. L. Day, A. Tikoo, R. Burke, C. Wrobel, R. L. Moritz, R. J. Simpson, D. L. Vaux. 2002. HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins. J Biol Chem. 277, 445-454 DOI ScienceOn |
13 | Potter S. Z., J. S. Valentine. 2003. The perplexing role of copper-zinc superoxide dismutase in amyotrophic lateral sclerosis (Lou Gehrig's disease). J Biol Inorg Chem. 8, 373-80 DOI |
14 | Saito A., T. Hayashi, S. Okuno, T. Nishi, P. H. Chan. 2004. Modulation of the Omi/HtrA2 signaling pathway after transient focal cerebral ischemia in mouse brains that overexpress SOD1. Brain Res Mol Brain Res. 127, 89-95 DOI ScienceOn |
15 | Seong Y. M., J. Y. Choi, H. J. Park, K. J. Kim, S. G. Ahn, G. H. Seong, I. K. Kim, S. Kang, H. Rhim. 2004. Autocatalytic processing of HtrA2/Omi is essential for induction of caspase-dependent cell death through antagonizing XIAP. J Biol Chem. 279, 37588-96 DOI ScienceOn |
16 | Seong Y. M., H. J. Park, G. H. Seong, J. Y. Choi, S. J. Yoon, B. R. Min, S. Kang, H. Rhim. 2004. N-terminal truncation circumvents proteolytic degradation of the human HtrA2/Omi serine protease in Escherichia coli: rapid purification of a proteolytically active HtrA2/Omi. Protein Expr Purif. 33, 200-8 DOI ScienceOn |
17 | Takeuchi H, Y. Kobayashi, S. Ishigaki, M. Doyu, G. Sobue. 2002. Mitochondrial localization of mutant superoxide dismutase 1 triggers caspase-dependent cell death in a cellular model of familial amyotrophic lateral sclerosis. J Biol Chem. 277, 50966-72 DOI ScienceOn |
18 | Jones J. M., P. Datta, S. M. Srinivasula, W. Ji, S. Gupta, Z. Zhang, E. Davies, G. Hajnoczky, T. L. Saunders, M. L. Van Keuren, T. Fernandes-Alnemri, M. H. Meisler, E. S. Alnemri. 2003. Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice. Nature. 425, 721-7 DOI ScienceOn |
19 | van Gurp M., N. Festjens, G. van Loo, X. Saelens, P. Vandenabeele. 2003. Mitochondrial intermembrane proteins in cell death. Biochem Biophys Res Commun. 304, 487-97 DOI ScienceOn |
20 | Higgins C. M., C. Jung, Z. Xu. 2003. ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes. BMC Neurosci. 4, 16 DOI ScienceOn |
21 | Kim S. S., K. H. Kim, H. J. Park, E. H. Hur, H. Rhim. 2005. Inhibitory effect of the N-termnal GST on the Tautomerase activity of marcrophage migration inhibitory factor. J. Life Science. 15, 961-967 과학기술학회마을 DOI ScienceOn |
22 | Li W, S. M. Srinivasula, J. Chai, P. Li, J. W. Wu, Z. Zhang, E. S. Alnemri, Y. Shi. 2002. Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi. Nat Struct Biol. 9, 436-41 DOI ScienceOn |
23 | Martins L. M., B. E. Turk, V. Cowling, A. Borg, E. T. Jarrell, L. C. Cantley, J. Downward. 2003. Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi. J Biol Chem. 278, 49417-27 DOI ScienceOn |
24 | Miller A. F. 2004. Superoxide dismutases: active sites that save, but a protein that kills. Curr Opin Chem Biol. 8, 162-8 DOI ScienceOn |
25 | Nam M. K., H. M. Park, J. Y. Choi, H. J. Park, K. C. Chung, S. Kang, H. Rhim, 2005. The expression patterns of Human parkin in E. coli and mammalian cells. J. Life Science. 15, 916-922 과학기술학회마을 DOI ScienceOn |