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http://dx.doi.org/10.5352/JLS.2006.16.1.162

Effects of Eucalyptus and Geranium on Production of IL-2 and IL-4 in Mouse Splenocytes  

Cha Bong Kyu (Dept. of Microbiology, Kosin University College of Medicine)
Chang Myung Woong (Dept. of Microbiology, Kosin University College of Medicine)
Jeong Young Kee (Dept. of Life Science and Biotechnology, Dong-Eui University)
Kim Kwang Hyuk (Dept. of Microbiology, Kosin University College of Medicine)
Publication Information
Journal of Life Science / v.16, no.1, 2006 , pp. 162-167 More about this Journal
Abstract
Aromatherpy is the controlled use of essential oils to promote health and well-being. In this work we have investigated the effect of eucalyptus and geranium on the production of interleukin-2 (IL-2) and interleukin4 (IL-4). Mouse splenocytes were incubated with essential oils. The culture supernatants of mouse splenocytes exposed with these oils were harvested to assay IL-2 and IL-4 production. The quantitative changes of IL-2 in splenocytes culture supernatants after exposure with these oils were decreased at high doses, but increased at low doses. But its of IL-4 were increased generally at high doses of eucalyptus. In case of the exposure of geranium, its of IL-4 were dose-dependently increased. These kinds of essential oils showed the probability to improve IL-2- and IL-4-related immune responses at the optimum exposure.
Keywords
Eucalyptus; geranium; IL-2; IL-4; aromatherapy;
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