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http://dx.doi.org/10.5352/JLS.2005.15.5.834

Effects of Mulberry fruits Extracts on Serum Lipid Level in Ovariectomized Rats  

Choi Kyung-Ha (Department of Food science and Nutrition, Silla University)
Park Mi-Hwa (Department of Food science and Nutrition, Silla University)
Kim Mihyang (Department of Food science and Nutrition, Silla University)
Publication Information
Journal of Life Science / v.15, no.5, 2005 , pp. 834-839 More about this Journal
Abstract
The aim of this study was to evaluate the effects of three different mulberry cultivars extracts on serum lipid contents in ovariectomized estrogen-deficient rats. Sprague-Dawley female rats were randomly assigned to the following groups: sham-operated rats (sham), ovariectomized control rats (OVX-control), ovariectomized rats supplemented with $ 80\% $ ethyl alcohol extracts from various kinds of Tajikistan mulberry (OVX-TM), Korea mulberry (OVX-KM) and China mulberry (OVX-CM) at 200mg/kg bw/day, respectively. The mulberry extracts were orally administrated at 1mL per day. The body weights of OVX rats were significantly heavier than the sham-operated rats at all values (p <0.05). The ovariectomy caused an expected increasing in the levels of serum total cholesterol and triglyceride. The serum HDL-cholesterol level on the OVX-TM, OVX-KM and OVX-CM groups were higher than in the OVX-control group.
Keywords
Mulberry; cholesterol; triglyceride; HDL-cholesterol; ovariectomized rat;
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