Browse > Article
http://dx.doi.org/10.5352/JLS.2005.15.2.311

Effect of Herbicide Paraquat on Electron Donor and Acceptor  

Kim Mi-Lim (Faculty of Cuisine & Nutrition, Daegu Haany University)
Choi Kyung-Ho (Department of Food Science and Nutrition, Daegu Catholic University)
Publication Information
Journal of Life Science / v.15, no.2, 2005 , pp. 311-315 More about this Journal
Abstract
When paraquat was added to the bacterial membrane or mitochondrial suspension, the mixture turned dark blue, but the color was disappeared by aeration. The same phenomenon was seen when electrons were supplied to the paraquat. Blue color appeared from near the cathode, and then spreaded to whole transit system. Coloration was accelerated by addition of alkali, but the color was reduced by addition of acid or oxygen. Paraquat exhibited absorption at ultraviolet region by electron transfer at the concentrations as low as 1.0 mM which did not exert difficulty in showing color reaction. Paraquat caused the increase of the optical density at 340 nm by electron transit, and an aspect of that had a strong resemblance to NADH. The acute toxic action of paraquat seemes to depend on inhibition of energy metabolism cased by paraquat action of electron donor and acceptor.
Keywords
Paraquat; electron; donor; acceptor;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Bhatnagar, R. S. and Hussaim, M. Z. 1979. Involvement of superoxide in the paraquat-induced enhancement of lung collagen synthesis in organ culture. Biochem. Biophys. Res. Commun. 819, 71-76
2 Shinohara, T. and Seto, Y. 1987. Inhibitory effects of paraquat and its related compound on the acetylcholinesterase activies of human erythrocytes. Agric. Biol. Chem. 51(8), 2131-2138   DOI
3 Neumann, S., Guter. and Simon, H. 1984. On a Nonpyridine nucleotide-dependent 2-oxo acid reducrase with extremely broad substrate specificity. Eur. Congr. Biotechnol. 1, 377-382
4 Norman, M. A. and Fuerst, E. P. 1997. Interactions of cations with paraquat in leaf sections of resistant and sensitive biotypes of Conyza bonariensis. Pestic. Biochem. Physiol. 57, 181-191   DOI   ScienceOn
5 Qi, Y. M., Greenfield, P. F. and Reid, S 1996. Evaluation of a simple protein-free medium that supports high levels of monoclonal antibody production. Cytotechnol. 21(2), 95-109   DOI   ScienceOn
6 Shibata, K. and Iwai, K. 1988. Effect of dietary paraquat on the enzyme activies involved in tryptophan-niacin metabolism in rats. Agric. Biol. Chem. 50(1), 255-256
7 Shinohara, T. and Seto, Y. 1986. In vitro inhibition of acetylchlinesterase by paraquat. Agric. Biol. Chem. 50(1), 255-256   DOI
8 Simon, H., Bader, J., Guther, H., Neumann, S. and Thanos, J. 1984. Biohydrogenation and electromicrobial and electronenzymatic reduction methods for the preparation of chiral compounds. Ann. N. Y. Acad. Sci. 9, 171-185
9 Thanos I. C. G. and Simon, H. 1987. Electro-enzymic vioIogenmediated streospecefic reduction of 2-enoates with free and immobilized enoate reductase on cellulose filters or modified carbon electrodes. J. Biotechnol. 6(1), 13-29   DOI   ScienceOn
10 Tidswell, E. C, Thompson, A. N. and Gareth Morris, J. 1991. Selection in chemostat culture of a mutant strain of Clostridium thiobutyricm improved in its reduction of ketones, J. Microbiol. 35, 317-322
11 Vaishampayan, A. 1985. Muta genicity of bipyridilium salts in a $N_2$-fixing cyanobacterium. Microbios. 43, 53-65
12 Harvey, B. M. R. and Harper, D. B. 1978. Mechanism of paraquat tolerance in perenial ryegrass : II. role of superoxide dismutase, catalase and peroxidase. Plant Cell Environ. 1, 211-215   DOI
13 Fuerst, E. P. and Vaughn, K. C. 1990. Mechanisms of paraquat resistance. Weed Technol. 4, 150-156
14 Gunther, H., Neumann, S. and Simon, H. 1987. 2-Oxocarboxy late reductase from proteus specids and its use for the preparation of (2r)-hydroxy acids. J. Biotechnol. 5(1), 53-65   DOI   ScienceOn
15 Harvey, B. M. R. and Harper, D. B. 1978. Mechanism of paraquat tolerance in perenial ryegrass: I. uptake, metabolism and translocation of paraquat. Plant Cell Environ. 1. 203-209   DOI
16 Hassan, H. and Fridovich, I. 1978. Superoxide radical and the oxygen enhancement of the toxicity of paraquaton E. coli. J. Biol. chem. 253, 8143-8148
17 Kim, C. S. and Choi, K. H. 1991. Effect of paraquat treatment on fatty acid compasition of menbrane lipids of Bacillus megaterium and Saccharomyces cerevisiae. Hyosung j. Appl. Sci. 53-61
18 Kim, M. L. and Choi, K. H. 1994. Inhibitory action of the paraquat on Superoxide dismutase of Escherichia coli. J. Korean Soc. Food Nutr. 23(5), 849-855
19 Klier, K., Kresze, G., Werbitzky, O. and Simon, H. 1987. The microbial redutive splitting of the N-O yond of dihydrooxazines; An alternative to the chemical reduction. Tetrahedron letters. 28(24), 2677-2680   DOI   ScienceOn
20 Liochev, S. and Fridovich, I. 1986. Variate-stimulated oxidation of NAD(P)H by biomembrane is a superoxid einitiated radical chain reaction, Arch. Biochem. Biophys. 250, 139-145   DOI   ScienceOn
21 Bus, J. S. Aust, S. D. and Gibson, J. E. 1975. A possible mechanism for paraquat toxicity. Res. Commun. Pathol. Pharmacol. 31, 31-38
22 Murray, K., Gull, K. and Dickson, A. J. 1995. Dichloroactate increases cell and product yields in hybridoma batchcultures improved production of anti-paraquat monoclonal antibody. Biochem. Soc. Trans. 23(4), 585s
23 Bowles, M.R., Mulbern, T. D., Gordon, R. B., Inglis, H. R., Sharpe, I. A., Cogill, J. L. and Pond, S. M. 1997. Herbicidespecific single chain antibody engineering for use in poisoning therapy. J. Biochem. 122(1), 101-108   DOI   ScienceOn
24 Thanos I. C. G. and Simon, H. 1987. Electro-enzymic viologenmediated streospecefic reduction of 2-enoates with free and immobilized enoate reductase on cellulose filters or modified carbon electrodes. J. Biotechnol. 6(1), 13-29   DOI   ScienceOn
25 Frank,D. M. F., Arora, P. K.,Blumer,J. L. and Sayre, L. M. 1987. Model study on the bioreduction of paraquat, ${Mpp}^+$, and analogs. evidence against a 'Redox cycling' mechanism in mptp neurotoxicity. Biochem. Biophys. Res. commun. 147(3), 1095-1104   DOI   ScienceOn
26 Chun, J. C., Ma, S. Y, Kim, S. E. and Lee, H. J 1997. Physiological responses of Rhehmannia glutinosa to paraquat and its tolerance mechanism. Pestic. Biochem. Physiol. 59, 51-63   DOI   ScienceOn
27 Cserhati, T. and Valko, K. 1991. Interaction of diquat and paraquat with glutathione studied by means of chargetransfer chromatography. J. Liq. Chromatogry. 14(20), 3657-3671   DOI
28 Halliwell, B. 1978. Biochemical mechanie- accounting for toxic action of oxygen on living organisms : the sky role of superoxide dismutase. Cell Biol. Int. Rep. 2, 113-128   DOI   ScienceOn