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http://dx.doi.org/10.5352/JLS.2005.15.2.261

Investigation of Conserved Genes in Microorganism  

Lee Dong-Geun (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Lee Jae-Hwa (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Lee Sang-Hyeon (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Ha Bae-Jin (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Shim Doo-Hee (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Park Eun-Kyung (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Kim Jin-Wook (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Li Hua-Yue (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Nam Chun-Suk (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Kim Nam Young (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Lee Eo-Jin (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Back Jin-Wook (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Ha Jong-Myung (Marine-Biotechnology Center for Bio-functional material Industries, Department of Bioscience and Biotechnology, College of Engineering, Silla University)
Publication Information
Journal of Life Science / v.15, no.2, 2005 , pp. 261-266 More about this Journal
Abstract
To figure out conserved genes in 66 microbial species and measuring the degree of conservation, analyses based on COG (Clusters of Orthologous Groups of proteins) algorithm were applied. Sixty-six microbial genomes, including three eukaryotes, hold 63 conserved orthologs in common. The majority $(82.5\%)$ of the conserved genes was related to translation, meaning the importance of protein in living creatures. Ribosomal protein S12 (COG0048) and L14 (COG0093) were more conserved genes than others from the distance value analysis. Phylogenetically related microbes grouped in genome analysis by average and standard deviation of 63 conserved genes. The 63 conserved genes, found in this research, would be useful in basic research and applied ones such as antibiotic development.
Keywords
conserved gene; microbial genome; ortholog; COG (Clusters of Orthologous Groups of proteins);
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