[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.3340/jkns.2022.0004

Neuromodulation for Trigeminal Neuralgia

Chung, Moonyoung (Department of Neurosurgery, Soonchunhyang University Bucheon Hospital, Soonchunhayng University College of Medicine)
Huh, Ryoong (Department of Neurosurgery, Incheon St. Mary's Hospital, The Catholic University of Korea)

Publication Information

Journal of Korean Neurosurgical Society / v.65, no.5, 2022 , pp. 640-651 More about this Journal

Abstract

Clinical studies on neuromodulation intervention for trigeminal neuralgia have not yet shown promising results. This might be due to the fact that the pathophysiology of chronic trigeminal neuropathy is not yet fully understood. Chronic trigeminal neuropathy includes trigeminal autonomic neuropathy, painful trigeminal neuropathy, and persistent idiopathic facial pain. This disorder is caused by complex abnormalities in the pain processing system, which is comprised of the affective, emotional, and sensory components, rather than mere abnormal sensation. Therefore, integrative understanding of the pain system is necessary for appropriate neuromodulation of chronic trigeminal neuropathy. The possible neuromodulation targets that participate in complex pain processing are as follows : the ventral posterior medial nucleus, periaqueductal gray, motor cortex, nucleus accumbens, subthalamic nucleus, globus pallidus internus, anterior cingulate cortex, hypothalamus, sphenopalatine ganglion, and occipital nerve. In conclusion, neuromodulation interventions for trigeminal neuralgia is yet to be elucidated; future advancements in this area are required.

Keywords

Trigeminal neuralgia; Trigeminal caudal nucleus; Deep brain stimulation; Facial pain;

Citations & Related Records

Reference

1	Ben-Haim S, Mirzadeh Z, Rosenberg WS : Deep brain stimulation for intractable neuropathic facial pain. Neurosurg Focus 45 : E15, 2018
2	Berridge KC, Kringelbach ML : Pleasure systems in the brain. Neuron 86 : 646-664, 2015 DOI
3	Blake P, Burstein R : Emerging evidence of occipital nerve compression in unremitting head and neck pain. J Headache Pain 20 : 76, 2019
4	Burchiel KJ, Raslan AM : Contemporary concepts of pain surgery. J Neurosurg 130 : 1039-1049, 2019 DOI
5	Cappon D, Ryterska A, Lagrata S, Miller S, Akram H, Hyam J, et al. : Ventral tegmental area deep brain stimulation for chronic cluster headache: effects on cognition, mood, pain report behaviour and quality of life. Cephalalgia 39 : 1099-1110, 2019 DOI
6	Chiang MC, Bowen A, Schier LA, Tupone D, Uddin O, Heinricher MM : Parabrachial complex: a hub for pain and aversion. J Neurosci 39 : 8225-8230, 2019 DOI
7	Clelland CD, Zheng Z, Kim W, Bari A, Pouratian N : Common cerebral networks associated with distinct deep brain stimulation targets for cluster headache. Cephalalgia 34 : 224-230, 2014 DOI
8	Bushnell MC, Ceko M, Low LA : Cognitive and emotional control of pain and its disruption in chronic pain. Nat Rev Neurosci 14 : 502-511, 2013 DOI
9	Ebel H, Rust D, Tronnier V, Boker D, Kunze S : Chronic precentral stimulation in trigeminal neuropathic pain. Acta Neurochir (Wien) 138 : 1300-1306, 1996 DOI
10	Cruccu G, Di Stefano G, Truini A : Trigeminal neuralgia. N Engl J Med 383 : 754-762, 2020 DOI
11	Fontaine D, Bozzolo E, Chivoret N, Paquis P, Lanteri-Minet M : Salvage treatment of trigeminal neuralgia by occipital nerve stimulation. Cephalalgia 34 : 307-310, 2014 DOI
12	Godfrey N, Borgland SL : Diversity in the lateral hypothalamic input to the ventral tegmental area. Neuropharmacology 154 : 4-12, 2019 DOI
13	Hamani C, Fonoff ET, Parravano DC, Silva VA, Galhardoni R, Monaco BA, et al. : Motor cortex stimulation for chronic neuropathic pain: results of a double-blind randomized study. Brain 144 : 2994-3004, 2021 DOI
14	Huh R, Song IU, Chung M : Neuropsychological consequences of pallidal deep brain stimulation altering brain networks. J Clin Neurosci 54 : 50-56, 2018 DOI
15	Gouveia FV, Hamani C, Fonoff ET, Brentani H, Alho EJL, De Morais RMCB, et al. : Amygdala and hypothalamus: historical overview with focus on aggression. Neurosurgery 85 : 11-30, 2019 DOI
16	Ferbinteanu J : Memory systems 2018 - towards a new paradigm. Neurobiol Learn Mem 157 : 61-78, 2019 DOI
17	French JD, Verzeano M, Magoun HW : An extralemniscal sensory system in the brain. AMA Arch Neurol Psychiatry 69 : 505-518, 1953 DOI
18	Fuller PM, Sherman D, Pedersen NP, Saper CB, Lu J : Reassessment of the structural basis of the ascending arousal system. J Comp Neurol 519 : 933-956, 2011 DOI
19	Gruber D, Sudmeyer M, Deuschl G, Falk D, Krauss JK, Mueller J, et al. : Neurostimulation in tardive dystonia/dyskinesia: a delayed start, sham stimulation-controlled randomized trial. Brain Stimul 11 : 1368-1377, 2018 DOI
20	Hosobuchi Y, Adams JE, Rutkin B : Chronic thalamic stimulation for the control of facial anesthesia dolorosa. Arch Neurol 29 : 158-161, 1973 DOI
21	Hosobuchi Y, Rossier J, Bloom FE, Guillemin R : Stimulation of human periaqueductal gray for pain relief increases immunoreactive beta-endorphin in ventricular fluid. Science 203 : 279-281, 1979 DOI
22	Ilyas A, Pizarro D, Romeo AK, Riley KO, Pati S : The centromedian nucleus: anatomy, physiology, and clinical implications. J Clin Neurosci 63 : 1-7, 2019 DOI
23	Coffey RJ : Deep brain stimulation for chronic pain: results of two multicenter trials and a structured review. Pain Med 2 : 183-192, 2001 DOI
24	Leone M, Proietti Cecchini A : Deep brain stimulation in headache. Cephalalgia 36 : 1143-1148, 2016 DOI
25	Parmar M, Sharma N, Modgill V, Naidu P : Comparative evaluation of surgical procedures for trigeminal neuralgia. J Maxillofac Oral Surg 12 : 400-409, 2013 DOI
26	Kumar K, Toth C, Nath RK : Deep brain stimulation for intractable pain: a 15-year experience. Neurosurgery 40 : 736-746, 1997 DOI
27	Lai HY, Younce JR, Albaugh DL, Kao YC, Shih YY : Functional MRI reveals frequency-dependent responses during deep brain stimulation at the subthalamic nucleus or internal globus pallidus. Neuroimage 84 : 11-18, 2014 DOI
28	Khan S, Schoenen J, Ashina M : Sphenopalatine ganglion neuromodulation in migraine: what is the rationale? Cephalalgia 34 : 382-391, 2014 DOI
29	Balint E, Csillag A : Nucleus accumbens subregions: hodological and immunohistochemical study in the domestic chick (gallus domesticus). Cell Tissue Res 327 : 221-230, 2007 DOI
30	Baldo BA : Prefrontal cortical opioids and dysregulated motivation: a network hypothesis. Trends Neurosci 39 : 366-377, 2016 DOI
31	Basbaum AI, Bautista DM, Scherrer G, Julius D : Cellular and molecular mechanisms of pain. Cell 139 : 267-284, 2009 DOI
32	Basbaum AI, Fields HL : Endogenous pain control mechanisms: review and hypothesis. Ann Neurol 4 : 451-462, 1978 DOI
33	Bendtsen L, Zakrzewska JM, Heinskou TB, Hodaie M, Leal PRL, Nurmikko T, et al. : Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia. Lancet Neurol 19 : 784-796, 2020 DOI
34	Boivie J, Meyerson BA : A correlative anatomical and clinical study of pain suppression by deep brain stimulation. Pain 13 : 113-126, 1982 DOI
35	Rasskazoff SY, Slavin KV : Neuromodulation for cephalgias. Surg Neurol Int 4 : S136-S150, 2013
36	Pereira EA, Aziz TZ : Neuropathic pain and deep brain stimulation. Neurotherapeutics 11 : 496-507, 2014 DOI
37	Pereira EA, Green AL, Aziz TZ : Deep brain stimulation for pain. Handb Clin Neurol 116 : 277-294, 2013 DOI
38	Rapisarda A, Ioannoni E, Izzo A, Montano N : What are the results and the prognostic factors of motor cortex stimulation in patients with facial pain? A systematic review of the literature. Eur Neurol 84 : 151-156, 2021 DOI
39	Reynolds DV : Surgery in the rat during electrical analgesia induced by focal brain stimulation. Science 164 : 444-445, 1969 DOI
40	Richardson DE, Akil H : Pain reduction by electrical brain stimulation in man. Part 1: acute administration in periaqueductal and periventricular sites. J Neurosurg 47 : 178-183, 1977 DOI
41	Sadikot AF, Rymar VV : The primate centromedian-parafascicular complex: anatomical organization with a note on neuromodulation. Brain Res Bull 78 : 122-130, 2009 DOI
42	Lainez MJ, Marti AS : Sphenopalatine ganglion stimulation in cluster headache and other types of headache. Cephalalgia 36 : 1149-1155, 2016 DOI
43	Calzavara R, Mailly P, Haber SN : Relationship between the corticostriatal terminals from areas 9 and 46, and those from area 8a, dorsal and rostral premotor cortex and area 24c: an anatomical substrate for cognition to action. Eur J Neurosci 26 : 2005-2024, 2007 DOI
44	Chung M, Huh R : Different clinical course of pallidal deep brain stimulation for phasic- and tonic-type cervical dystonia. Acta Neurochir (Wien) 158 : 171-180, 2016 DOI
45	Schjerling L, Hjermind LE, Jespersen B, Madsen FF, Brennum J, Jensen SR, et al. : A randomized double-blind crossover trial comparing subthalamic and pallidal deep brain stimulation for dystonia. J Neurosurg 119 : 1537-1545, 2013 DOI
46	Schmahmann JD, Pandya DN : Disconnection syndromes of basal ganglia, thalamus, and cerebrocerebellar systems. Cortex 44 : 1037-1066, 2008 DOI
47	Levy RM, Lamb S, Adams JE : Treatment of chronic pain by deep brain stimulation: long term follow-up and review of the literature. Neurosurgery 21 : 885-893, 1987 DOI
48	Keifer OP Jr, Diaz A, Campbell M, Bezchlibnyk YB, Boulis NM : Occipital nerve stimulation for the treatment of refractory occipital neuralgia: a case series. World Neurosurg 105 : 599-604, 2017 DOI
49	Kim HJ, Paek SH, Kim JY, Lee JY, Lim YH, Kim MR, et al. : Chronic subthalamic deep brain stimulation improves pain in parkinson disease. J Neurol 255 : 1889-1894, 2008 DOI
50	Kruger MT, Avecillas-Chasin JM, Heran MKS, Naseri Y, Sandhu MK, Polyhronopoulos NE, et al. : Directional deep brain stimulation can target the thalamic "sweet spot" for improving neuropathic dental pain. Oper Neurosurg (Hagerstown) 21 : 81-86, 2021 DOI
51	Levi V, Cordella R, D'Ammando A, Tringali G, Dones I, Messina G, et al. : Dorsal anterior cingulate cortex (ACC) deep brain stimulation (DBS): a promising surgical option for the treatment of refractory thalamic pain syndrome (TPS). Acta Neurochir (Wien) 161 : 1579-1588, 2019 DOI
52	Levy R, Deer TR, Henderson J : Intracranial neurostimulation for pain control: a review. Pain Physician 13 : 157-165, 2010
53	Shulman R, Turnbull IM, Diewold P : Psychiatric aspects of thalamic stimulation for neuropathic pain. Pain 13 : 127-135, 1982 DOI
54	Sims-Williams HP, Javed S, Pickering AE, Patel NK : Characterising the analgesic effect of different targets for deep brain stimulation in trigeminal anaesthesia dolorosa. Stereotact Funct Neurosurg 94 : 174-181, 2016 DOI
55	Smith Y, Raju DV, Pare JF, Sidibe M : The thalamostriatal system: a highly specific network of the basal ganglia circuitry. Trends Neurosci 27 : 520-527, 2004 DOI
56	Tsubokawa T, Katayama Y, Yamamoto T, Hirayama T, Koyama S : Chronic motor cortex stimulation for the treatment of central pain. Acta Neurochir Suppl (Wien) 52 : 137-139, 1991 DOI
57	Spina A, Mortini P, Alemanno F, Houdayer E, Iannaccone S : Trigeminal neuralgia: toward a multimodal approach. World Neurosurg 103 : 220-230, 2017 DOI
58	Stuber GD, Britt JP, Bonci A : Optogenetic modulation of neural circuits that underlie reward seeking. Biol Psychiatry 71 : 1061-1067, 2012 DOI
59	Tepper SJ, Stillman MJ : Cluster headache: potential options for medically refractory patients (when all else fails). Headache 53 : 1183-1190, 2013 DOI
60	Varela C : Thalamic neuromodulation and its implications for executive networks. Front Neural Circuits 8 : 69, 2014
61	Venkatraman A, Edlow BL, Immordino-Yang MH : The brainstem in emotion: a review. Front Neuroanat 11 : 15, 2017
62	Vogt BA : Pain and emotion interactions in subregions of the cingulate gyrus. Nat Rev Neurosci 6 : 533-544, 2005 DOI
63	Vukovic Cvetkovic V, Jensen RH : Neurostimulation for the treatment of chronic migraine and cluster headache. Acta Neurol Scand 139 : 4-17, 2019 DOI
64	Weber K : Neuromodulation and devices in trigeminal neuralgia. Headache 57 : 1648-1653, 2017 DOI
65	Mazars GJ : Intermittent stimulation of nucleus ventralis posterolateralis for intractable pain. Surg Neurol 4 : 93-95, 1975
66	Mallory GW, Abulseoud O, Hwang SC, Gorman DA, Stead SM, Klassen BT, et al. : The nucleus accumbens as a potential target for central poststroke pain. Mayo Clin Proc 87 : 1025-1031, 2012 DOI
67	Marchand S, Kupers RC, Bushnell CM, Duncan GH : Analgesic and placebo effects of thalamic stimulation. Pain 105 : 481-488, 2003 DOI
68	Marques A, Chassin O, Morand D, Pereira B, Debilly B, Derost P, et al. : Central pain modulation after subthalamic nucleus stimulation: a crossover randomized trial. Neurology 81 : 633-640, 2013 DOI
69	Melzack R, Wall PD : Pain mechanisms: a new theory. Science 150 : 971-979, 1965 DOI
70	Wiech K : Deconstructing the sensation of pain: the influence of cognitive processes on pain perception. Science 354 : 584-587, 2016 DOI
71	Weigel R, Krauss JK : Center median-parafascicular complex and pain control. Review from a neurosurgical perspective. Stereotact Funct Neurosurg 82 : 115-126, 2004 DOI
72	Moro E, Piboolnurak P, Arenovich T, Hung SW, Poon YY, Lozano AM : Pallidal stimulation in cervical dystonia: clinical implications of acute changes in stimulation parameters. Eur J Neurol 16 : 506-512, 2009 DOI
73	Schoenen J, Jensen RH, Lanteri-Minet M, Lainez MJ, Gaul C, Goodman AM, et al. : Stimulation of the sphenopalatine ganglion (SPG) for cluster headache treatment. Pathway CH-1: a randomized, sham-controlled study. Cephalalgia 33 : 816-830, 2013 DOI
74	Sewards TV, Sewards MA : The medial pain system: neural representations of the motivational aspect of pain. Brain Res Bull 59 : 163-180, 2002 DOI
75	Shephard MK, Macgregor EA, Zakrzewska JM : Orofacial pain: a guide for the headache physician. Headache 54 : 22-39, 2014 DOI
76	Meyerson BA, Lindblom U, Linderoth B, Lind G, Herregodts P : Motor cortex stimulation as treatment of trigeminal neuropathic pain. Acta Neurochir Suppl (Wien) 58 : 150-153, 1993
77	Miller S, Watkins L, Matharu M : Treatment of intractable chronic cluster headache by occipital nerve stimulation: a cohort of 51 patients. Eur J Neurol 24 : 381-390, 2017 DOI
78	Ossipov MH, Dussor GO, Porreca F : Central modulation of pain. J Clin Invest 120 : 3779-3787, 2010 DOI
79	Maarbjerg S, Di Stefano G, Bendtsen L, Cruccu G : Trigeminal neuralgia - diagnosis and treatment. Cephalalgia 37 : 648-657, 2017 DOI
80	Nandi D, Aziz T, Carter H, Stein J : Thalamic field potentials in chronic central pain treated by periventricular gray stimulation -- a series of eight cases. Pain 101 : 97-107, 2003 DOI
81	Parent A, Hazrati LN : Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop. Brain Res Brain Res Rev 20 : 91-127, 1995 DOI
82	Adams JE : Naloxone reversal of analgesia produced by brain stimulation in the human. Pain 2 : 161-166, 1976 DOI
83	William A, Azad TD, Brecher E, Cherry T, Bernstein I, Bruce DM, et al. : Trigeminal and sphenopalatine ganglion stimulation for intractable craniofacial pain--case series and literature review. Acta Neurochir (Wien) 158 : 513-520, 2016 DOI
84	Young RF, Kroening R, Fulton W, Feldman RA, Chambi I : Electrical stimulation of the brain in treatment of chronic pain. Experience over 5 years. J Neurosurg 62 : 389-396, 1985 DOI
85	Abdallat M, Saryyeva A, Blahak C, Wolf ME, Weigel R, Loher TJ, et al. : Centromedian-parafascicular and somatosensory thalamic deep brain stimulation for treatment of chronic neuropathic pain: a contemporary series of 40 patients. Biomedicines 9 : 731, 2021