1 |
Atkinson GP, Nozell SE, Benveniste ETN : NF-kappaB and STAT3 signaling in glioma: targets for future therapies. Expert Rev Neurother 10 : 575-586, 2010
DOI
|
2 |
Batash R, Asna N, Schaffer P, Francis N, Schaffer M : Glioblastoma multiforme, diagnosis and treatment; recent literature review. Curr Med Chem 24 : 3002-3009, 2017
|
3 |
Charras A, Arvaniti P, Le Dantec C, Arleevskaya MI, Zachou K, Dalekos GN, et al. : JAK inhibitors suppress innate epigenetic reprogramming: a promise for patients with Sjogren's syndrome. Clin Rev Allergy Immunol 58 : 182-193, 2020
DOI
|
4 |
Cheng Z, Fu J, Liu G, Zhang L, Xu Q, Wang SY : Angiogenesis in JAK2 V617F positive myeloproliferative neoplasms and ruxolitinib decrease VEGF, HIF-1 enesis in JAK2 V617F positive cells. Leuk Lymphoma 59 : 196-203, 2018
DOI
|
5 |
Clara CA, Marie SK, de Almeida JR, Wakamatsu A, Oba-Shinjo SM, Uno M, et al. : Angiogenesis and expression of PDGF-C, VEGF, CD105 and HIF- in human glioblastoma. Neuropathology 34 : 343-352, 2014
DOI
|
6 |
Delen E, Doganlar O, Doganlar ZB, Delen O : Inhibition of the invasion of human glioblastoma U87 cell line by ruxolitinib: a molecular player of miR-17 and miR-20a regulating JAK/STAT pathway. Turk Neurosurg 30 : 182-189, 2020
|
7 |
George J, Banik NL, Ray SK : Knockdown of hTERT and concurrent treatment with interferon-gamma inhibited proliferation and invasion of human glioblastoma cell lines. Int J Biochem Cell Biol 42 : 1164-1173, 2010
DOI
|
8 |
Del Duca D, Werbowetski T, Del Maestro RF : Spheroid preparation from hanging drops: characterization of a model of brain tumor invasion. J Neurooncol 67 : 295-303, 2004
DOI
|
9 |
Fetell MR, Housepian EM, Oster MW, Cote DN, Sisti MB, Marcus SG, et al. : Intratumor administration of beta-interferon in recurrent malignant gliomas. A phase I clinical and laboratory study. Cancer 65 : 78-83, 1990
DOI
|
10 |
Fogelman D, Cubillo A, Garcia-Alfonso P, Miron MLL, Nemunaitis J, Flora D, et al. : Randomized, double-blind, phase two study of ruxolitinib plus regorafenib in patients with relapsed/refractory metastatic colorectal cancer. Cancer Med 7 : 5382-5393, 2018
DOI
|
11 |
Jensen KV, Cseh O, Aman A, Weiss S, Luchman HA : The JAK2/STAT3 inhibitor pacritinib effectively inhibits patient-derived GBM brain tumor initiating cells in vitro and when used in combination with temozolomide increases survival in an orthotopic xenograft model. PLoS One 12 : e0189670, 2017
DOI
|
12 |
Haile WB, Gavegnano C, Tao S, Jiang Y, Schinazi RF, Tyor WR : The Janus kinase inhibitor ruxolitinib reduces HIV replication in human macrophages and ameliorates HIV encephalitis in a murine model. Neurobiol Dis 92(Pt B) : 137-143, 2016
DOI
|
13 |
Han ES, Wen W, Dellinger TH, Wu J, Lu SA, Jove R, et al. : Ruxolitinib synergistically enhances the anti-tumor activity of paclitaxel in human ovarian cancer. Oncotarget 9 : 24304-24319, 2018
DOI
|
14 |
Honda S, Sadatomi D, Yamamura Y, Nakashioya K, Tanimura S, Takeda K : WP1066 suppresses macrophage cell death induced by inflammasome agonists independently of its inhibitory effect on STAT3. Cancer Sci 108 : 520-527, 2017
DOI
|
15 |
Hurwitz HI, Uppal N, Wagner SA, Bendell JC, Beck JT, Wade SM 3rd, et al. : Randomized, double-blind, phase II study of ruxolitinib or placebo in combination with capecitabine in patients with metastatic pancreatic cancer for whom therapy with gemcitabine has failed. J Clin Oncol 33 : 4039-4047, 2015
DOI
|
16 |
Jain RK, di Tomaso E, Duda DG, Loeffler JS, Sorensen AG, Batchelor TT : Angiogenesis in brain tumours. Nat Rev Neurosci 8 : 610-622, 2007
DOI
|
17 |
Kaur B, Khwaja FW, Severson EA, Matheny SL, Brat DJ, Van Meir EG : Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis. Neuro Oncol 7 : 134-153, 2005
DOI
|
18 |
Kim EK, Chung DS, Shin HJ, Hong YK : Inhibitory effect of IFN-beta, on the Antitumor activity of celecoxib in U87 glioma model. J Korean Neurosurg Soc 46 : 552-557, 2009
DOI
|
19 |
Li H, Liang Q, Wang L : Icaritin inhibits glioblastoma cell viability and glycolysis by blocking the IL-6/Stat3 pathway. J Cell Biochem 120 : 7257-7264, 2019
DOI
|
20 |
Knupfer MM, Knupfer H, Van Gool S, Domula M, Wolff JE : Interferon gamma inhibits proliferation and hyaluronic acid adhesion of human malignant glioma cells in vitro. Cytokine 12 : 409-412, 2000
DOI
|
21 |
Loboda A, Jozkowicz A, Dulak J : HIF-1 and HIF-2 transcription factors--similar but not identical. Mol Cells 29 : 435-442, 2010
DOI
|
22 |
Mukthavaram R, Ouyang X, Saklecha R, Jiang P, Nomura N, Pingle SC, et al. : Effect of the JAK2/STAT3 inhibitor SAR317461 on human glioblastoma tumorspheres. J Transl Med 13 : 269, 2015
DOI
|
23 |
Ohno M, Natsume A, Kondo Y, Iwamizu H, Motomura K, Toda H, et al. : The modulation of microRNAs by type I IFN through the activation of signal transducers and activators of transcription 3 in human glioma. Mol Cancer Res 7 : 2022-2030, 2009
DOI
|
24 |
Price SJ, Gillard JH : Imaging biomarkers of brain tumour margin and tumour invasion. Br J Radiol 84 Spec No 2 : S159-S167, 2011
DOI
|
25 |
Priyanka R, Muralidharan NP : Interferons and interferon therapy. J Pharm Sci Res 6 : 400-403, 2014
|
26 |
Schneider CA, Rasband WS, Eliceiri KW : NIH Image to ImageJ: 25 years of image analysis. Nat Methods 9 : 671-675, 2012
DOI
|
27 |
Silginer M, Nagy S, Happold C, Schneider H, Weller M, Roth P : Autocrine activation of the IFN signaling pathway may promote immune escape in glioblastoma. Neuro Oncol 19 : 1338-1349, 2017
DOI
|
28 |
Tate MC, Aghi MK : Biology of angiogenesis and invasion in glioma. Neurotherapeutics 6 : 447-457, 2009
DOI
|
29 |
Wakabayashi T, Kayama T, Nishikawa R, Takahashi H, Hashimoto N, Takahashi J, et al. : A multicenter phase I trial of combination therapy with interferon- and temozolomide for high-grade gliomas (INTEGRA study): the final report. J Neurooncol 104 : 573-577, 2011
DOI
|
30 |
Vallatos A, Al-Mubarak HFI, Birch JL, Galllagher L, Mullin JM, Gilmour L, et al. : Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region. J Magn Reson Imaging 50 : 529-540, 2019
DOI
|
31 |
Wei J, Ma L, Li C, Pierson CR, Finlay JL, Lin J : Targeting upstream kinases of STAT3 in human medulloblastoma cells. Curr Cancer Drug Targets 19 : 571-582, 2019
DOI
|
32 |
Weiswald LB, Bellet D, Dangles-Marie V : Spherical cancer models in tumor biology. Neoplasia 17 : 1-15, 2015
DOI
|