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http://dx.doi.org/10.3340/jkns.2018.0003

Treatment Decisions of World Health Organization Grade II and III Ependymomas in Molecular Era  

Jung, Tae-Young (Department of Neurosurgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School)
Jung, Shin (Department of Neurosurgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School)
Kook, Hoon (Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School)
Baek, Hee-Jo (Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School)
Publication Information
Journal of Korean Neurosurgical Society / v.61, no.3, 2018 , pp. 312-318 More about this Journal
Abstract
Surgery and radiotherapy are mainstays of treatment for ependymomas (EPNs). Recent molecular subgrouping could be superior to histopathological grading for predicting the prognosis of patients with EPNs. Gross total resection is an effective treatment approach regardless of its locations or pathologic grades. Adjuvant therapeutic strategies could be decided based on molecular subgrouping with risk-stratification. Information of histologic-molecular biology is now providing clues to therapeutic insights.
Keywords
Ependymoma; Biology; Molecular medicine; Prognosis; Therapeutics;
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