Novel Genetic Variants Associated with Lumbar Spondylosis in Koreans : A Genome-Wide Association Study |
Kim, Hyun Ah
(Division of Rheumatology, Hallym University Sacred Heart Hospital)
Heo, Seong Gu (Department of Medical Genetics, Hallym University College of Medicine) Park, Ji Wan (Department of Medical Genetics, Hallym University College of Medicine) Jung, Young Ok (Division of Rheumatology, Gangnam Sacred Heart Hospital) |
1 | Altshuler D, Daly MJ, Lander ES : Genetic mapping in human disease. Science 322 : 881-888, 2008 DOI |
2 | Battie MC, Videman T, Gibbons LE, Fisher LD, Mannine H, Gill K : 1995 Volvo Award in clinical sciences. Determinants of lumbar disc degeneration. A study relating lifetime exposures and magnetic resonance imaging findings in identical twins. Spine 20 : 2601-2612, 1995 DOI |
3 | Carmon KS, Gong X, Yi J, Thomas A, Liu Q : RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling. Proc Natl Acad Sci U S A 111 : E1221-E1229, 2014 DOI |
4 | Cho NH, Jung YO, Lim SH, Chung CK, Kim HA : The prevalence and risk factors of low back pain in rural community residents of Korea. Spine (Phila Pa 1976) 37 : 2001-2010, 2012 DOI |
5 | Eskola PJ, Lemmela S, Kjaer P, Solovieva S, Mannikko M, Tommerup N, et al. : Genetic association studies in lumbar disc degeneration: a systematic review. PLoS One 7 : e49995, 2012 DOI |
6 | Gavenis K, Schumacher C, Schneider U, Eisfeld J, Mollenhauer J, Schmidt-Rohlfing B : Expression of ion channels of the TRP family in articular chondrocytes from osteoarthritic patients: changes between native and in vitro propagated chondrocytes. Mol Cell Biochem 321 : 135-43, 2009 DOI |
7 | Glinka A, Dolde C, Kirsch N, Huang YL, Kazanskaya O, Inqelfinger D, et al. : LGR4 and LGR5 are R-spondin receptors mediating Wnt/-catenin and Wnt/PCP signalling. EMBO Rep 12 : 1055-1061, 2011 DOI |
8 | Lane NE, Nevitt MC, Genant HK, Hochberg MC : Reliability of new indices of radiographic osteoarthritis of the hand and hip and lumbar disc degeneration. J Rheumatol 20 : 1911-1918, 1993 |
9 | Matsui H, Kanamori M, Ishihara H, Yudoh K, Naruse Y, Tsuji H : Familial predisposition for lumbar degenerative disc disease. A case-control study. Spine (Phila Pa 1976) 23 : 1029-1034, 1998 DOI |
10 | Mazerbourg S, Bouley DM, Sudo S, Klein CA, Zhang JV, Kawamura K, et al. : Leucine-rich repeat-containing, G protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality. Mol Endocrinol 18 : 2241-2254, 2004 DOI |
11 | Muraki S, Oka H, Akune T, Mabuchi A, En-yo Y, Yoshida M, et al. : Prevalence of radiographic lumbar spondylosis and its association with low back pain in elderly subjects of population-based cohorts: the ROAD study. Ann Rheum Dis 68 : 1401-1406, 2009 DOI |
12 | Ostling P, Bjork JK, Roos-Mattjus P, Roos-Mattjus P, Mezger V, Sistonen L : Heat shock factor 2 (HSF2) contributes to inducible expression of hsp genes through interplay with HSF1. J Biol Chem 282 : 7077-7086, 2007 DOI |
13 | Pye SR, Reid DM, Smith R, Adams JE, Nelson K, Silman AJ, et al. : Radiographic features of lumbar disc degeneration and self-reported back pain. J Rheumatol 31 : 753-758, 2004 |
14 | Rabbee N, Speed TP : A genotype calling algorithm for affymetrix SNP arrays. Bioinformatics 22 : 7-12, 2006 DOI |
15 | Ryder JJ, Garrison K, Song F, Hooper L, Skinner J, Loke Y, et al. : Genetic associations in peripheral joint osteoarthritis and spinal degenerative disease: a systematic review. Ann Rheum Dis 67 : 584-591, 2008 |
16 | Sambrook PN, MacGregor AJ, Spector TD : Genetic influences on cervical and lumbar disc degeneration: a magnetic resonance imaging study in twins. Arthritis Rheum 42 : 366-372, 1999 DOI |
17 | Sharp CA, Roberts S, Evans H, Brown SJ : Disc cell clusters in pathological human intervertebral discs are associated with increased stress protein immunostaining. Eur Spine J 18 : 1587-1594, 2009 DOI |
18 | Spector TD, Cicuttini F, Baker J, Loughlin J, Hart D : Genetic influences on osteoarthritis in women: a twin study. BMJ 312 : 940-943, 1996 DOI |
19 | Smolders LA, Meij BP, Onis D, Riemers FM, Bergknut N, Wubbolts R, et al. : Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies. Arthritis Res Ther 29 : R23, 2013 |
20 | Song YQ, Cheung KM, Ho DW, Poon SC, Chiba K, Kawaguchi Y, et al. : Association of the asporin D14 allele with lumbar-disc degeneration in Asians. Am J Hum Genet 82 : 744-747, 2008 DOI |
21 | Suzuki Y, Kodama D, Goto S, Togari A : Involvement of TRP channels in the signal transduction of bradykinin in human osteoblasts. Biochem Biophys Res Commun 410 : 317-321, 2011 DOI |
22 | van Tulder MW, Assendelft WJ, Koes BW, Bouter LM : Spinal radiographic findings and nonspecific low back pain. A systematic review of observational studies. Spine (Phila Pa 1976) 22 : 427-434, 1997 DOI |
23 | Williams FM, Bansal AT, van Meurs JB, Bell JT, Meulenbelt I, Suri P, et al. : Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects. Ann Rheum Dis 72 : 1141-1148, 2013 DOI |
24 | Williams FM, Popham M, Hart DJ, de Schepper E, Biema-Zeinstra S, Hofman A, et al. : GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women. Arthritis Rheum 63 : 708-712, 2011 DOI |
25 | Zhai G, van Meurs JB, Livshits G, Meulenbelt L, Valdes AM, Soranzo N, et al. : A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium. J Med Genet 46 : 614-616, 2009 DOI |