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http://dx.doi.org/10.3340/jkns.2014.55.1.61

Solitary Cavernous Sinus Neurosarcoidosis Mimicking Neurosyphilis  

Kim, Dong Ha (Department of Neurosurgery, Pusan National University Hospital, Pusan National University School of Medicine)
Cho, Won Ho (Department of Neurosurgery, Pusan National University Hospital, Pusan National University School of Medicine)
Cho, Kyu Sup (Department of Otolaryngology, Pusan National University Hospital, Pusan National University School of Medicine)
Cha, Seong Heon (Department of Neurosurgery, Pusan National University Hospital, Pusan National University School of Medicine)
Publication Information
Journal of Korean Neurosurgical Society / v.55, no.1, 2014 , pp. 61-63 More about this Journal
Abstract
A differential diagnosis between neurosarcoidosis and neurosyphilis is particularly problematic in patients with a positive serologic result for syphilis. We report here a patient with a solitary cavernous sinus sarcoidosis who had a history of syphilis and showed rapidly progressing cavernous sinus syndrome. A transsphenoidal biopsy was performed and a histopathologic examination revealed a non-caseating granuloma with an asteroid body. His facial pain disappeared after steroid therapy. He received oral prednisolone for one year. A follow-up magnetic resonance imaging of the brain revealed resolution of the mass over the cavernous sinus. Particularly in patients with a history of syphilis, neurosyphilis should be included in a differential diagnosis of neurosarcoidosis.
Keywords
Neurosarcoidosis; Neurosyphilis; Sarcoidosis; Cavernous sinus;
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