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http://dx.doi.org/10.3340/jkns.2011.50.3.235

Radiation-Induced Glioblastoma Multiforme in a Remitted Acute Lymphocytic Leukemia Patient  

Joh, Dae-Won (Department of Neurosurgery, Kyung Hee University Hospital, Kyung Hee University School of Medicine)
Park, Bong-Jin (Department of Neurosurgery, Kyung Hee University Hospital, Kyung Hee University School of Medicine)
Lim, Young-Jin (Department of Neurosurgery, Kyung Hee University Hospital, Kyung Hee University School of Medicine)
Publication Information
Journal of Korean Neurosurgical Society / v.50, no.3, 2011 , pp. 235-239 More about this Journal
Abstract
Radiation therapy has been widely applied for cancer treatment. Childhood acute lymphocytic leukemia (ALL), characterized by frequent central nervous system involvement, is a well documented disease for the effect of prophylactic cranio-spinal irradiation. Irradiation, however, acts as an oncogenic factor as a delayed effect and it is rare that glioblastoma multiforme develops during the remission period of ALL. We experienced a pediatric radiation-induced GBM patient which developed during the remission period of ALL, who were primarily treated with chemotherapeutic agents and brain radiation therapy for the prevention of central nervous system (CNS) relapse. Additionally, we reviewed the related literature regarding on the effects of brain irradiation in childhood and on the prognosis of radiation induced GBM.
Keywords
Radiation; Glioblastoma multiforme; Acute lymphocytic leukemia;
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1 Fontana M, Stanton C, Pompili A, Amadori S, Mandelli F, Meloni G, et al. : Late multifocal gliomas in adolescents previously treated for acute lymphoblastic leukemia. Cancer 60 : 1510-1518, 1987   DOI   ScienceOn
2 Grabb PA, Kelly DR, Fulmer BB, Palmer C : Radiation-induced glioma of the spinal cord. Pediatr Neurosurg 25 : 214-219, 1996   DOI   ScienceOn
3 Inati A, Sallan SE, Cassady JR, Hitchcock-Bryan S, Clavell LA, Belli JA, et al. : Efficacy and morbidity of central nervous system "prophylaxis" in childhood acute lymphoblastic leukemia : eight years' experience with cranial irradiation and intrathecal methotrexate. Blood 61 : 297-303, 1983
4 Bouillot S, Vignes JR, Guerin J, Dubus P, Vital A : Leukenic dissemination wihin a glioblastoma in a patient with chronic lymphoid leukemia. Clin Neuropathol 22 : 10-13, 2003
5 Brat DJ, James CD, Jedlicka AE, Connolly DC, Chang E, Castellani RJ, et al. : Molecular genetic alterations in radiation-induced astrocytomas. Am J Pathol 154 : 1431-1438, 1999   DOI   ScienceOn
6 Cahan WG, Woodard HQ, Higinbotham NL, Stewart FW, Coley BL : Sarcoma arising in irradiated bone : report of eleven cases. 1948. Cancer 82 : 8-34, 1998   DOI   ScienceOn
7 Chung CK, Stryker JA, Cruse R, Vannuci R, Towfighi J : Glioblastoma multiforme following prophylactic cranial irradiation and intrathecal methotrexate in a child with acute lymphocytic leukemia. Cancer 47 : 2563-2566, 1981   DOI   ScienceOn
8 Yaris N, Erduran E, Celep F, Yavuz M, Reis A : Secondary glioblastoma multiforme with a new translocation t(3;3)(q21;q26) following treatment of acute lymphoblastic leukemia. Turk J Pediatr 47 : 98-99, 2005
9 Tsutsumi S, Yasumoto Y, Ito M : Pediatric multicentric glioma occurring after cranial irradiation. J Clin Neurosci 16 : 1086-1088, 2009   DOI   ScienceOn
10 Walter AW, Hancock ML, Pui CH, Hudson MM, Ochs JS, Rivera GK, et al. : Secondary brain tumors in children treated for acute lymphoblastic leukemia at St Jude Children's Research Hospital. J Clin Oncol 16 : 3761-3767, 1998   DOI
11 Shah KC, Rajshekhar V : Glioblastoma multiforme in a child with acute lymphoblastic leukemia : case report and review of literature. Neurol India 52 : 375-377, 2004
12 Salvati M, Artico M, Caruso R, Rocchi G, Orlando ER, Nucci F : A report on radiation-induced gliomas. Cancer 67 : 392-397, 1991   DOI   ScienceOn
13 Salvati M, D'Elia A, Melone GA, Brogna C, Frati A, Raco A, et al. : Radio-induced gliomas : 20-year experience and critical review of the pathology. J Neurooncol 89 : 169-177, 2008   DOI   ScienceOn
14 Schoenberg BS, Christine BW, Whisnant JP : The descriptive epidemiology of primary intracranial neoplasms : the Connecticut experience. Am J Epidemiol 104 : 499-510, 1976   DOI
15 Symss NP, Pande A, Chakravanthy MV, Ramamurthi R : Glioblastoma multiforme occurring in a child with acute lymphoblastic leukemia. J Pediatr Neurosci 1 : 63-65, 2006   DOI
16 Neglia JP, Robison LL, Stovall M, Liu Y, Packer RJ, Hammond S, et al. : New primary neoplasms of the central nervous system in survivors of childhood cancer : a report from the Childhood Cancer Survivor Study. J Natl Cancer Inst 98 : 1528-1537, 2006   DOI   ScienceOn
17 Trouillas P, Menaud G, De The G, Aimard G, Devic M : [Epidemiological study of primary tumors of the neuraxis in the Rhone-Alps region. Quantitative data on the etiology and geographical distribution of 1670 tumors]. Rev Neurol (Paris) 131 : 691-708, 1975
18 Perez CA, Brady LW : Principles and Practice of Radiation Oncology, ed 2. Philadelphia : Lippincott Co, 1992, pp1-63
19 Saenger EL, Silverman FN, Sterling TD, Turner ME : Neoplasia following therapeutic irradiation for benign conditions in childhood. Radiology 74 : 889-904, 1960   DOI
20 Muzumdar DP, Desai K, Goel A : Glioblastoma multiforme following prophylactic cranial irradiation and intrathecal methotrexate in a child with acute lymphoblastic leukaemia : a case report. Neurol India 47 : 142-144, 1999
21 Jones A : Supervoltage X-ray therapy of intracranial tumours. Ann R Coll Surg Engl 27 : 310-354, 1960
22 Nishio S, Morioka T, Inamura T, Takeshita I, Fukui M, Sasaki M, et al. : Radiation-induced brain tumours : potential late complications of radiation therapy for brain tumours. Acta Neurochir (Wien) 140 : 763-770, 1998   DOI   ScienceOn
23 Ohgaki H, Kleihues P : Epidemiology and etiology of gliomas. Acta Neuropathol 109 : 93-108, 2005   DOI   ScienceOn
24 Pejsa V, Grgurevic I, Pazanin L, Lang N, Grgurevic L, Jaksic O : Multicentric glial brain tumors of a varying degree of differentiation in patient with chronic lymphocytic leukemia. Am J Hematol 79 : 50-53, 2005   DOI   ScienceOn
25 Modan B, Baidatz D, Mart H, Steinitz R, Levin SG : Radiation induce head and neck tumors. Lancet 1 : 277-279, 1974
26 Loning L, Zimmermann M, Reiter A, Kaatsch P, Henze G, Riehm H, et al. : Secondary neoplasms subsequent to Berlin-Frankfurt-Münster therapy of acute lymphoblastic leukemia in childhood : significantly lower risk without cranial radiotherapy. Blood 95 : 2770-2775, 2000
27 Mann I, Yates PC, Ainslie JP : Unusual case of double primary orbital tumour. Br J Ophthalmol 37 : 758-762, 1953   DOI   ScienceOn
28 Menon R, Muzumdar D, Shah A, Goel A : Glioblastoma multiforme following cranial irradiation and chemotherapy for acute lymphocytic leukaemia. Report of 3 cases. Pediatr Neurosurg 43 : 369-374, 2007   DOI   ScienceOn
29 Donson AM, Erwin NS, Kleinschmidt-DeMasters BK, Madden JR, Addo-Yobo SO, Foreman NK : Unique molecular characteristics of radiation-induced glioblastoma. J Neuropathol Exp Neurol 66 : 740-749, 2007   DOI   ScienceOn