Browse > Article
http://dx.doi.org/10.3340/jkns.2010.48.2.173

Undetermined Fibrous Tumor with Calcification in the Cerebellopontine Angle  

Cheon, Se-Hun (Department of Neurosurgery, Anam Hosipital, Korea University College of Medicine)
Kang, Shin-Hyuk (Department of Neurosurgery, Anam Hosipital, Korea University College of Medicine)
Park, Kyung-Jae (Department of Neurosurgery, Anam Hosipital, Korea University College of Medicine)
Chung, Yong-Gu (Department of Neurosurgery, Anam Hosipital, Korea University College of Medicine)
Publication Information
Journal of Korean Neurosurgical Society / v.48, no.2, 2010 , pp. 173-176 More about this Journal
Abstract
In this report, we introduce an undetermined fibrous tumor with calcification occurring in the cerebellopontine angle (CPA). A 51-year-old woman was admitted with a short history of dizziness. Computed tomography and magnetic resonance images revealed a $2{\times}2{\times}2\;cm$ sized mass at the left CPA which was round and calcified. There was no dura or internal auditory canal involvement. At surgery, the tumor was located at the exit of 7th and 8th cranial nerve complex. It was very firm, bright yellow and well encapsulated. Histologic findings revealed that the tumor was predominantly composed of fibrous component, scant spindle cells and dystrophic calcification. Immunohistochemical staining demonstrated positive for vimentin and negative for epithelial membrane antigen (EMA), S-100 protein, CD34, factor XIIIa and smooth muscle actin. The diagnosis was not compatible with meningioma, schwannoma, metastatic brain tumors, and other fibrous tumors. Although the tumor was resected in total, long term follow-up monitoring is necessary due to the possibility of recurrence.
Keywords
Calcification; Cerebellopontine angle; Immunohistochemistry; Tumor;
Citations & Related Records

Times Cited By Web Of Science : 0  (Related Records In Web of Science)
Times Cited By SCOPUS : 0
연도 인용수 순위
  • Reference
1 Kim KA, Gonzalez I, McComb JG, Giannotta SL : Unusual presentations of cerebral solitary fibrous tumors : report of four cases. Neurosurgery 54 : 1004-1009; discussion 1009, 2004   DOI   ScienceOn
2 Mito K, Kashima K, Daa T, Kondoh Y, Miura T, Kawahara K, et al. : Multiple calcifying fibrous tumors of the pleura. Virchows Arch 446 : 78-81, 2005   DOI   ScienceOn
3 McLean CA, Laidlaw JD, Brownhill DS, Gonzales MF : Recurrence of acoustic neurilemmoma as a malignant spindle-cell neoplasm. J Neurosurg 73 : 946-950, 1990   DOI
4 Lunsford LD, Niranjan A, Flickinger JC, Maitz A, Kondziolka D : Radiosurgery of vestibular schwannomas : summary of experience in 829 cases. J Neurosurg 102 : 195-199, 2005   DOI   ScienceOn
5 Jang KS, Oh YH, Han HX, Chon SH, Chung WS, Park CK, et al. : Calcifying fibrous pseudotumor of the pleura. Ann Thorac Surg 78 : 87-88, 2004   DOI   ScienceOn
6 Kocak A, Cayli SR, Sarac K, Aydn NE : Intraventricular solitary fibrous tumor : an unusual tumor with radiological, ultrastructural, and immunohistochemical evaluation : case report. Neurosurgery 54 : 213-216; discussion 216-217, 2004   DOI   ScienceOn
7 Lau SK, Weiss LM : Calcifying fibrous tumor of the adrenal gland. Hum Pathol 38 : 656-659, 2007   DOI   ScienceOn
8 Klemperer P, Rabin CB : Primary neoplasms of the pleura : a report of five cases. Arch Pathol 11 : 385-412, 1931
9 Katoh M, Aida T, Imamura H, Aoki T, Yoshino M, Kashiwazaki D, et al. : Calcified vestibular schwannoma in the cerebellopontine angle. J Clin Neurosci 14 : 1207-1209, 2007   DOI   ScienceOn
10 Kawahara K, Yasukawa M, Nakagawa K, Katsura H, Nagano T, Iwasaki T : Multiple calcifying fibrous tumor of the pleura. Virchows Arch 447 : 1007-1008, 2005   DOI   ScienceOn
11 Tihan T, Viglione M, Rosenblum MK, Olivi A, Burger PC : Solitary fibrous tumours in the central nervous system. A clinicopathologic review of 18 cases and comparison to meningeal hemangiopericytomas. Arch Pathol Lab Med 127 : 432-439, 2003
12 Huang L, Ling X, Xu W, Fu Y, Gao W : MRI differentiation diagnosis of occupying lesions in cerebellopontine angle area. Chin Ger J Clin Oncol 5 : 197-199, 2006   DOI   ScienceOn
13 Wright DH, Naul LG, Hise JH, Bauserman SC : Intraventricular fibroma : MR and pathologic comparison. AJNR Am J Neuroradiol 14 : 491-492, 1993
14 Dervan PA, Tobin B, O'Connor M : Solitary (localized) fibrous mesothelioma : evidence against mesothelial cell origin. Histopathology 10 : 867-875, 1986   DOI
15 Westra WH, Gerald WL, Rosai J : Solitary fibrous tumor. Consistent CD34 immunoreactivity and occurrence in the orbit. Am J Surg Pathol 18 : 992-998, 1994   DOI   ScienceOn
16 Fetsch JF, Montgomery EA, Meis JM : Calcifying fibrous pseudotumor. Am J Surg Pathol 17 : 502-508, 1993   DOI   ScienceOn
17 Hori E, Kurimoto M, Fukuda O, Takahashi C, Nagai S, Oya T, et al. : Recurrent intracranial solitary fibrous tumor initially diagnosed as hemangiopericytoma. Brain Tumor Pathol 24 : 31-34, 2007   DOI   ScienceOn
18 Bikmaz K, Cosar M, Kurtkaya-Yapicier O, Iplikcioglu AC, Gokduman CA : Recurrent solitary fibrous tumour in the cerebellopontine angle. J Clin Neurosci 12 : 829-832, 2005   DOI   ScienceOn
19 Brian DM, Caterina G, Michael JL : Ganglioglioma in the cerebellopontine angle in a child. Case report and review of the literature. J Neurosurg 107 : 292-296, 2007   DOI   ScienceOn
20 Wada T, Suzuki M, Beppu T, Arai H, Yoshida Y, Ogawa A, et al. : A case of subcortical meningioma. Acta Neurochir (Wien) 142 : 209- 213, 2000   DOI   ScienceOn
21 Milligan BD, Giannini C, Link MJ : Calcifying fibrous pseudotumor of the pleura : a rare location. Ann Thorac Surg 76 : 2081-2082, 2003   DOI   ScienceOn
22 Biggs ND, Fagan PA, Turner JJ, Doust B : Solitary fibrous tumor of the cerebello-pontine angle. Skull Base Surgery 9 : 295-299, 1999   DOI
23 Voss NF, Vrionis FD, Heilman CB, Robertson JH : Meningiomas of the cerebellopontine angle. Surg Neurol 53 : 439-446; discussion 446- 447, 2000   DOI   ScienceOn
24 Nascimento AF, Ruiz R, Hornick JL, Fletcher CD : Calcifying fibrous 'pseudotumor' : clinicopathologic study of 15 cases and analysis of its relationship to inflammatory myofibroblastic tumor. Int J Surg Pathol 10 : 189-196, 2002   DOI   ScienceOn
25 Asaoka K, Barrs DM, Sampson JH, McElveen JT Jr, Tucci DL, Fukushima T : Intracanalicular meningioma mimicking vestibular schwannoma. Am J Neuroradiol 23 : 1493-1496, 2002
26 Shibata K, Yuki D, Sakata K : Multiple calcifying fibrous pseudotumors disseminated in the pleura. Ann Thorac Surg 85 : 3-5, 2008   DOI   ScienceOn