Evaluation of Spinal Fusion Using Bone Marrow Derived Mesenchymal Stem Cells with or without Fibroblast Growth Factor-4 |
Seo, Hyun-Sung
(Department of Neurosurgery, School of Medicine, Inha University)
Jung, Jong-Kwon (Department of Anesthesiology, School of Medicine, Inha University) Lim, Mi-Hyun (Department of Anesthesiology, School of Medicine, Inha University) Hyun, Dong-Keun (Department of Neurosurgery, School of Medicine, Inha University) Oh, Nam-Sik (Department of Neurosurgery, School of Medicine, Inha University) Yoon, Seung-Hwan (Department of Neurosurgery, School of Medicine, Inha University) |
1 | Boden SD, Martin GJ Jr, Morone M, Ugbo JL, Titus L, Hutton WC : The use of coralline hydroxyapatite with bone marrow, autogenous bone graft, or osteoinductive bone protein extract for posterolateral lumbar spine fusion. Spine 24 : 320-327, 1999 DOI ScienceOn |
2 | Cheng H, Jiang W, Phillips FM, Haydon RC, Peng Y, Zhou L, et al. : Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs). J Bone Joint Surg Am 85A : 1544-1552, 2003 |
3 | Choi SC, Kim SJ, Choi JH, Park CY, Shim WJ, Lim DS : Fibroblast growth factor-2 and -4 promote the proliferation of bone marrow mesenchymal stem cells by the activation of the PI3K-Akt and ERK1/2 signaling pathways. Stem Cells Dev 17 : 725-736, 2008 DOI ScienceOn |
4 | Dumont RJ, Dayoub H, Li JZ, Dumont AS, Kallmes DF, Hankins GR, et al : Ex vivo bone morphogenetic protein-9 gene therapy using human mesenchymal stem cells induces spinal fusion in rodents. Neurosurgery 51 : 1239-1244; discussion 1244-1245, 2002 DOI ScienceOn |
5 | Kuroda S, Kasugai S, Oida S, Iimura T, Ohya K, Ohyama T : Anabolic Anabolic effect of aminoterminally truncated fibroblast growth factor 4 (FGF4) on bone. Bone 25 : 431-437, 1999 DOI ScienceOn |
6 | Minamide A, Yoshida M, Kawakami M, Yamasaki S, Kojima H, Hashizume H, et al. : The use of cultured bone marrow cells in type I collagen gel and porous hydroxyapatite for posterolateral lumbar spine fusion. Spine 30 : 1134-1138, 2005 DOI ScienceOn |
7 | Miyazaki M, Sugiyama O, Tow B, Zou J, Morishita Y, Wei F, et al. : The effects of lentiviral gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats. J Spinal Disord Tech 21 : 372-379, 2008 DOI ScienceOn |
8 | Miyazaki M, Zuk PA, Zou J, Yoon SH, Wei F, Morishita Y, et al. : Comparison of human mesenchymal stem cells derived from adipose tissue and bone marrow for ex vivo gene therapy in rat spinal fusion model. Spine 33 : 863-869, 2008 DOI ScienceOn |
9 | Nakajima T, Iizuka H, Tsutsumi S, Kayakabe M, Takagishi K : Evaluation of posterolateral spinal fusion using mesenchymal stem cells : differences with or without osteogenic differentiation. Spine 32 : 2432-2436, 2007 DOI ScienceOn |
10 | Cheng SL, Lou J, Wright NM, Lai CF, Avioli LV, Riew KD : In vitro and in vivo induction of bone formation using a recombinant adenoviral vector carrying the human BMP-2 gene. Calcif Tissue Int 68 : 87-94, 2001 DOI ScienceOn |
11 | Fu TS, Chen WJ, Chen LH, Lin SS, Liu SJ, Ueng SW : Enhancement of posterolateral lumbar spine fusion using low-dose rhBMP-2 and cultured marrow stromal cells. J Orthop Res 27 : 380-384, 2009 DOI ScienceOn |
12 | Hasharoni A, Zilberman Y, Turgeman G, Helm GA, Liebergall M, Gazit D : Murine spinal fusion induced by engineered mesenchymal stem cells that conditionally express bone morphogenetic protein-2. J Neurosurg Spine 3 : 47-52, 2005 DOI ScienceOn |
13 | Lovinescu I, Koyama E, Pacifici M : Roles of FGF-10 on the development of diathrodial limb joints. Penn Dent J (Phila) 103 : 5, 9, 2003 |
14 | Vadala G, Studer RK, Sowa G, Spiezia F, Iucu C, Denaro V, et al. : Coculture of bone marrow mesenchymal stem cells and nucleus pulposus cells modulate gene expression profile without cell fusion. Spine 33 : 870-876, 2008 DOI ScienceOn |
15 | Konishi S, Nakamura H, Seki M, Nagayama R, Yamano Y : Hydroxyapatite granule graft combined with recombinant human bone morphogenic protein-2 for solid lumbar fusion. J Spinal Disord Tech 15 : 237-244, 2002 DOI ScienceOn |
16 | Lu SS, Zhang X, Soo C, Hsu T, Napoli A, Aghaloo T, et al. : The osteoinductive properties of Nell-1 in a rat spinal fusion model. Spine J 7 : 50-60, 2007 DOI ScienceOn |
17 | Kuroda S, Kondo H, Ohya K, Kasugai S : Bone increase in rat tibiae by local administration of amino-terminally truncated rhFGF-4(73-206). Tissue Eng 13 : 415-422, 2007 DOI ScienceOn |
18 | Lee K, Chan CK, Patil N, Goodman SB : Cell therapy for bone regeneration-Bench to bedside. J Biomed Mater Res B Appl Biomater 87 : 252-263 2008 |
19 | Franke Stenport V, Johansson CB, Sawase T, Yamasaki Y, Oida S : FGF-4 and titanium implants : a pilot study in rabbit bone. Clin Oral Implants Res 14 : 363-368, 2003 DOI ScienceOn |
20 | Kavanagh E, Church VL, Osborne AC, Lamb KJ, Archer CW, Francis-West PH, et al. : Differential regulation of GDF-5 and FGF-2/4 by immobilization in ovo exposes distinct roles in joint formation. Dev Dyn 235 : 826-834, 2006 DOI ScienceOn |
21 | Koga A, Tokuhashi Y, Ohkawa A, Nishimura T, Takayama K, Ryu J : Effects of fibronectin on osteoinductive capability of fresh iliac bone marrow aspirate in posterolateral spinal fusion in rabbits. Spine 33 : 1318-1323, 2008 DOI ScienceOn |
22 | Heise U, Osborn JF, Duwe F : Hydroxyapatite ceramic as a bone substitute. Int Orthop 14 : 329-338, 1990 |
23 | Risbud MV, Shapiro IM, Guttapalli A, Di Martino A, Danielson KG, Beiner JM, et al. : Osteogenic potential of adult human stem cells of the lumbar vertebral body and the iliac crest. Spine 31 : 83-89, 2006 DOI ScienceOn |
24 | Spivak JM, Hasharoni A : Use of hydroxyapatite in spine surgery. Eur Spine J 10 Suppl 2 : S197-S204, 2001 |
25 | Aslan H, Sheyn D, Gazit D : Genetically engineered mesenchymal stem cells : applications in spine therapy. Regen Med 4 : 99-108, 2009 DOI ScienceOn |
26 | Orii H, Sotome S, Chen J, Wang J, Shinomiya K : Beta-tricalcium phosphate (beta-TCP) graft combined with bone marrow stromal cells (MSCs) for posterolateral spine fusion. J Med Dent Sci 52 : 51-57, 2005 |
27 | Lee J, Kim JY, Kang IY, Kim HK, Han YM, Kim J : The EWS-Oct-4 fusion gene encodes a transforming gene. Biochem J 406 : 519-526, 2007 DOI ScienceOn |
28 | Riew KD, Wright NM, Cheng S, Avioli LV, Lou J : Induction of bone formation using a recombinant adenoviral vector carrying the human BMP-2 gene in a rabbit spinal fusion model. Calcif Tissue Int 63 : 357-360, 1998 DOI ScienceOn |
29 | Itoh S, Kikuchi M, Koyama Y, Takakuda K, Shinomiya K, Tanaka J : Development of a hydroxyapatite/collagen nanocomposite as a medical device. Cell Transplant 13 : 451-461, 2004 DOI ScienceOn |
30 | Farr J, Roura S, Prat-Vidal C, Soler-Botija C, Llach A, Molina CE, et al. : FGF-4 increases in vitro expansion rate of human adult bone marrow-derived mesenchymal stem cells. Growth Factors 25 : 71-76, 2007 DOI ScienceOn |
31 | Szpalski M, Gunzburg R : Recombinant human bone morphogenetic protein-2 : a novel osteoinductive alternative to autogenous bone graft? Acta Orthop Belg 71 : 133-148, 2005 ScienceOn |
32 | Siddappa R, Fernandes H, Liu J, van Blitterswijk C, de Boer J : The response of human mesenchymal stem cells to osteogenic signals and its impact on bone tissue engineering. Curr Stem Cell Res Ther 2 : 209-220, 2007 DOI ScienceOn |
33 | Minamide A, Yoshida M, Kawakami M, Okada M, Enyo Y, Hashizume H, et al. : The effects of bone morphogenetic protein and basic fibroblast growth factor on cultured mesenchymal stem cells for spine fusion. Spine 32 : 1067-1071, 2007 DOI ScienceOn |