[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.3340/jkns.2009.45.3.157

Stereotactic Radiosurgery with the CyberKnife for Pituitary Adenomas

Cho, Chul-Bum (Catholic Neuroscience Center, Department of Neurosurgery, St. Mary's Hospital, The Catholic University of Korea, College of Medicine)
Park, Hae-Kwan (Catholic Neuroscience Center, Department of Neurosurgery, St. Mary's Hospital, The Catholic University of Korea, College of Medicine)
Joo, Won-Il (Catholic Neuroscience Center, Department of Neurosurgery, St. Mary's Hospital, The Catholic University of Korea, College of Medicine)
Chough, Chung-Kee (Catholic Neuroscience Center, Department of Neurosurgery, St. Mary's Hospital, The Catholic University of Korea, College of Medicine)
Lee, Kyung-Jin (Catholic Neuroscience Center, Department of Neurosurgery, St. Mary's Hospital, The Catholic University of Korea, College of Medicine)
Rha, Hyoung-Kyun (Catholic Neuroscience Center, Department of Neurosurgery, St. Mary's Hospital, The Catholic University of Korea, College of Medicine)

Publication Information

Journal of Korean Neurosurgical Society / v.45, no.3, 2009 , pp. 157-163 More about this Journal

Abstract

Objective : In recent years, CyberKnife has emerged as an important treatment modality in the management of pituitary adenomas. Treatment results after performing CyberKnife and the complications of this procedure are reviewed. Methods : Twenty-six patients with pituitary adenomas received stereotactic radiosurgery with the CyberKnife (CKRS). The follow-up periods ranged from 7 months to 47 months (mean $\pm$ SD : $30{\pm}12.7$ months). The patients consisted of 17 with non-functioning adenomas, 3 with prolactinomas and 6 with acromegaly. The change in the tumor volume, visual acuity, hormonal function, and complications by this therapy were analyzed in each case. Results : The tumor control rate was 92.3%. Hormonal function was improved in all of the 9 (100%) functioning adenomas. Hormonal normalization was observed in 4 of the 9 (44%) patients with a mean duration of 16 months. In two patients (7.6%), visual acuity worsened due to cystic enlargement of the tumor after CKRS. No other complications were observed. Conclusion : CyberKnife is considered safe and effective in selected patients with pituitary adenomas. However, longer follow-up is required for a more complete assessment of late toxicity and treatment efficacy.

Keywords

CyberKnife; Pituitary adenoma;

Citations & Related Records

Times Cited By Web Of Science : 9 (Related Records In Web of Science)
Times Cited By SCOPUS : 7

Reference
Cited By SCOPUS

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9	(2009) Neurologia medico-chirurgica Stereotactic Radiosurgery/Radiotherapy for Pituitary Adenomas: A Review of Recent Literature / 50 (9) , 749
4	(2009) Neurosurgical focus Radiation treatment strategies for acromegaly / 29 (4) , E12
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6	(2009) Neurosurgery Long-term Outcomes After Gamma Knife Stereotactic Radiosurgery for Nonfunctional Pituitary Adenomas / 69 (6) , 1188
None	(2009) International Journal of endocrinology Surgery and Radiosurgery for Acromegaly: A Review of Indications, Operative Techniques, Outcomes, and Complications / 2012 (None) , 386401
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1	/ Neurologia Medico-Chirurgica
2	/ Neurosurgical focus [electronic resource]
3	/ International Journal of Medical Robotics and Computer Assisted Surgery
4	/ Neurosurgical focus [electronic resource]
5	/ Revue Medicale de Liege
6	/ Current Opinion in Endocrinology, Diabetes and Obesity
7	/ Neurosurgery

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