Neurochemical Characterization of the TRPV1-Positive Nociceptive Primary Afferents Innervating Skeletal Muscles in the Rats
![]() |
Shin, Dong-Su
(Department of Neurosurgery Seoul Medical Center)
Kim, Eun-Hyun (Department of Anatomy and Cell Biology College of Medicine Hanyang University) Song, Kwan-Young (Department of Neurosurgery Seoul Medical Center) Hong, Hyun-Jong (Department of Neurosurgery Seoul Medical Center) Kong, Min-Ho (Department of Neurosurgery Seoul Medical Center) Hwang, Se-Jin (Department of Anatomy and Cell Biology College of Medicine Hanyang University) |
1 | Hoheisel U, Lehmann-Willenbrock E, Mense S : Termination patterns of identified group II and III afferent fibres from deep tissues in the spinal cord of the cat. Neuroscience 28 : 495-507, 1989 DOI ScienceOn |
2 | Mense S : Nociception from skeletal muscle in relation to clinical muscle pain. Pain 54 : 241-289, 1993 DOI ScienceOn |
3 | Abrahams VC : Group III and IV receptors of skeletal muscle. Can J Physiol Pharmacol 64 : 509-514, 1986 DOI PUBMED ScienceOn |
4 | Ambalavanar R, Moritani M, Haines A, Hilton T, Dessem D : Chemical phenotypes of muscle and cutaneous afferent neurons in the rat trigeminal ganglion. J Comp Neurol 460 : 167-179, 2003 DOI ScienceOn |
5 | Aoki Y, Ohtori S, Takahashi K, Ino H, Ozawa T, Douya H, et al : P2X3-immunoreactive primary sensory neurons innervating lumbar intervertebral disc in rats. Brain Res 989 : 214-220, 2003 DOI ScienceOn |
6 | Bjorkman R, Hallman KM, Hedner J, Hedner T, Henning M : Acetaminophen blocks spinal hyperalgesia induced by NMDA and substance P. Pain 57 : 259-264, 1994 DOI ScienceOn |
7 | Gao Z, Henig O, Kehoe V, Sinoway LI, Li J : Vanilloid type 1 receptor and the acid-sensing ion channel mediate acid phosphate activation of muscle afferent nerves in rats. J Appl physiol 100 : 421-426, 2006 DOI ScienceOn |
8 | Ji RR, Baba H, Brenner GJ, Woolf CJ : Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity. Nat Neurosci 2 : 1114-1119, 1999 DOI ScienceOn |
9 | Lawson SN, Crepps BA, Perl ER : Relationship of substance P to afferent characteristics of dorsal root ganglion neurones in guinea-pig. J Physiol 505 Pt 1 : 177-191, 1997 DOI |
10 | Ling LJ, Honda T, Shimada Y, Ozaki N, Shiraishi Y, Sugiura Y : Central projection of unmyelinated (C) primary afferent fibers from gastrocnemius muscle in the guinea pig. J Comp Neurol 461 : 140-150, 2003 DOI ScienceOn |
11 | Widmann C, Gibson S, Jarpe MB, Johnson GL : Mitogen-activated protein kinase : conservation of a three-kinase module from yeast to human. Physiol Rev 79 : 143-180, 1999 DOI PUBMED |
12 | Nishiguchi J, Sasaki K, Seki S, Chancellor MB, Erickson KA, de Groat WC, et al : Effects of isolectin B4-conjugated saporin, a targeting cytotoxin, on bladder overactivity induced by bladder irritation. Eur J Neurosci 20 : 474-482, 2004 DOI ScienceOn |
13 | Petruska JC, Cooper BY, Gu JG, Rau KK, Johnson RD : Distribution of P2X1, P2X2, and P2X3 receptor subunits in rat primary afferents : relation to population markers and specific cell types. J Chem Neuroanat 20 : 141-162, 2000 DOI ScienceOn |
14 | Riedel W, Neeck G : Nociception, pain, and antinociception : current concepts. Z Rheumatol 60 : 404-415, 2001 DOI |
15 | Zimmer A, Zimmer AM, Baffi J, Usdin T, Reynolds K, Konig M : Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene. Proc Natl Acad Sci U S A 95 : 2630-2635, 1998 |
16 | Hoheisel U, Mense S : Long-term changes in discharge behaviour of cat dorsal horn neurones following noxious stimulation of deep tissues. Pain 36 : 239-247, 1989 DOI ScienceOn |
17 | Caterina MJ, Leffler A, Malmberg AB, Rosen TA, Levine JD, Julius D : Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288 : 306-313, 2000 DOI ScienceOn |
18 | Hwang SJ, Min Oh J, Valtschanoff JG : Expression of the vanilloid receptor TRPV1 in rat dorsal root ganglion neurons supports different roles of the receptor in visceral and cutaneous afferents. Brain Res 1047 : 261-266, 2005 DOI ScienceOn |
19 | Jami L : Golgi tendon organs in mammalian skeletal muscle : functional properties and central actions. Physiol Rev 72 : 623-666, 1992 DOI PUBMED |
20 | Kiss S, Yoshiyama M, Cao YQ, Basbaum AI, de Groat WC, Lecci A, et al : Impaired response to chemical irritation of the urinary tract in mice with disruption of the preprotachykinin gene. Neurosci Lett 313 : 57-60, 2001 DOI ScienceOn |
21 | Stucky CL, Lewin GR : Isolectin B(4)-positive and -negative nociceptors are functionally distinct. J Neurosci 19 : 6497-6505, 1999 DOI PUBMED |
22 | Hoheisel U, Reinohl J, Unger T, Mense S : Acidic pH and capsaicin activate mechanosensitive group IV muscle receptors in the rat. Pain 110 : 149-157, 2004 DOI ScienceOn |
23 | Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, et al : The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21 : 531-543, 1998 DOI ScienceOn |
24 | Guo A, Vulchanova L, Wang J, Li X, Elde R : Immunocytochemical localization of the vanilloid receptor 1 (VR1) : relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites. Eur J Neurosci 11 : 946-958, 1999 DOI ScienceOn |
25 | Ishizuka N, Mannen H, Hongo T, Sasaki S : Trajectory of group Ia afferent fibers stained with horseradish peroxidase in the lumbosacral spinal cord of the cat : three dimensional reconstructions from serial sections. J Comp Neurol 186 : 189-211, 1979 DOI ScienceOn |
26 | Ohtori S, Takahashi K, Chiba T, Takahashi Y, Yamagata M, Sameda H, et al : Fos expression in the rat brain and spinal cord evoked by noxious stimulation to low back muscle and skin. Spine 25 : 2425-2430, 2000 DOI ScienceOn |
27 | Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D : The capsaicin receptor : a heat-activated ion channel in the pain pathway. Nature 389 : 816-824, 1997 DOI ScienceOn |
28 | Gunthorpe MJ, Harries MH, Prinjha RK, Davis JB, Randall A : Voltage- and time-dependent properties of the recombinant rat vanilloid receptor (rVR1). J Physiol 525 Pt 3 : 747-759, 2000 DOI |
29 | Ambalavanar R, Moritani M, Moutanni A, Gangula P, Yallampalli C, Dessem D : Deep tissue inflammation upregulates neuropeptides and evokes nociceptive behaviors which are modulated by a neuropeptide antagonist. Pain 120 : 53-68, 2006 DOI ScienceOn |
30 | Willis WD, Trevino DL, Coulter JD, Maunz RA : Responses of primate spinothalamic tract neurons to natural stimulation of hindlimb. J Neurophysiol 37 : 358-372, 1974 DOI PUBMED |
31 | Jin SX, Zhuang ZY, Woolf CJ, Ji RR : p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. J Neurosci 23 : 4017-4022, 2003 DOI |
32 | Nichols ML, Allen BJ, Rogers SD, Ghilardi JR, Honore P, Luger NM, et al : Transmission of chronic nociception by spinal neurons expressing the substance P receptor. Science 286 : 1558-1561, 1999 DOI ScienceOn |
33 | Michael GJ, Priestley JV : Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its downregulation by axotomy. J Neurosci 19 : 1844-1854, 1999 DOI |
34 | Walker KM, Urban L, Medhurst SJ, Patel S, Panesar M, Fox AJ, et al : The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain. J Pharmacol Exp Ther 304 : 56-62, 2003 DOI ScienceOn |
35 | Karai L, Brown DC, Mannes AJ, Connelly ST, Brown J, Gandal M, et al : Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control. J Clin Invest 113 : 1344-1352, 2004 DOI |
36 | Kim SJ, Koh KS, Chung IH : The effect of sciatic nerve transection on the somatostatin and substance P cells in dorsal root ganglia of rats. J Korean Neurosurgical Soc 19 : 21-30, 1990 과학기술학회마을 |
37 | O'Brien C, Woolf CJ, Fitzgerald M, Lindsay RM, Molander C : Differences in the chemical expression of rat primary afferent neurons which innervate skin, muscle or joint. Neuroscience 32 : 493-502, 1989 DOI ScienceOn |
38 | Panneton WM, Gan Q, Juric R : The central termination of sensory fibers from nerves to the gastrocnemius muscle of the rat. Neuroscience 134 : 175-187, 2005 DOI ScienceOn |
39 | Kantor PF, Coetzee WA, Carmeliet EE, Dennis SC, Opie LH : Reduction of ischemic K+ loss and arrhythmias in rat hearts. Effect of glibenclamide, a sulfonylurea. Circ Res 66 : 478-485, 1990 DOI PUBMED ScienceOn |
40 | Dunn PM, Zhong Y, Burnstock G : P2X receptors in peripheral neurons. Prog Neurobiol 65 : 107-134, 2001 DOI ScienceOn |
41 | Avelino A, Cruz C, Nagy I, Cruz F : Vanilloid receptor 1 expression in the rat urinary tract. Neuroscience 109 : 787-798, 2002 DOI ScienceOn |
42 | Seger R, Krebs EG : The MAPK signaling cascade. Faseb J 9 : 726-735, 1995 DOI PUBMED |
43 | De Koninck Y, Ribeiro-da-Silva A, Henry JL, Cuello AC : Spinal neurons exhibiting a specific nociceptive response receive abundant substance P-containing synaptic contacts. Proc Natl Acad Sci USA 89 : 5073-5077, 1992 |
44 | Hwang SJ, Valtschanoff JG : Vanilloid receptor VR1-positive afferents are distributed differently at different levels of the rat lumbar spinal cord. Neurosci Lett 349 : 41-44, 2003 DOI ScienceOn |
45 | Silverman JD, Kruger L : Selective neuronal glycoconjugate expression in sensory and autonomic ganglia : relation of lectin reactivity to peptide and enzyme markers. J Neurocytol 19 : 789-801, 1990 DOI |
46 | Hwang SJ, Oh JM, Valtschanoff JG : The majority of bladder sensory afferents to the rat lumbosacral spinal cord are both IB4- and CGRP-positive. Brain Res 1062 : 86-91, 2005 DOI ScienceOn |
47 | Shortland PJ, Wang HF, Molander C : Transganglionic transport of the lectin soybean agglutinin (Glycine max) following injection into the sciatic nerve of the adult rat. J Neurocytol 27 : 233-245, 1998 DOI ScienceOn |
![]() |