Browse > Article

Primary Central Nervous System Lymphoma in Organ Recipient  

Hong, Ki-Sun (Department of Neurosurgery, Korea University Medical Center, Ansan Hospital)
Kim, Sang-Dae (Department of Neurosurgery, Korea University Medical Center, Ansan Hospital)
Lim, Dong-Jun (Department of Neurosurgery, Korea University Medical Center, Ansan Hospital)
Park, Jung-Yul (Department of Neurosurgery, Korea University Medical Center, Ansan Hospital)
Publication Information
Journal of Korean Neurosurgical Society / v.37, no.4, 2005 , pp. 296-299 More about this Journal
Abstract
We report a case of primary central nervous system(CNS) lymphoma in an organ recipient. A 33-years-old man who underwent a renal transplantation 3years previously presented with headache and vomiting. In Brain computed tomography scans and magnetic resonance images showed multiple periventricular cystic rim enhancing masses. Pathologic diagnosis by stereotactic biopsy revealed malignant non-Hodgkins B-cell lymphoma. After pathologic confirmation, methotrexate chemotherapy and whole brain radiation therapy were done. Having experienced such a case, the authors strongly recommend to add primary CNS lymphoma as one of the differential diagnoses to brain abscess, metastatic brain tumor and glioblastoma multiforme in cases of multiple ring enhancing periventricular lesions of immunocompromised patient or organ recipient.
Keywords
Primary central nervous system lymphoma; Organ recipient; Periventricular lesion; Ring enhancement;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Bataille B, Delwail V, Menet E, Vandermarcq P, Ingrand P, Wager M, et al : Primary intracerebral malignant lymphoma:report of 248 cases. J Neurosurg 92 : 261-266, 2000   DOI   ScienceOn
2 Schaefer PW, Grant PE, Ginzalez RG : Diffusion-weighted MR imaging of the brain. Radiology 217 : 331-345, 2000   DOI   PUBMED
3 Urasaki E, Yamada H, Tokimura T, Yokota A : T-cell type primary spinal intramedullary lymphoma associated with human T-cell lymphotropic virus type I after a renal transplant : case report. Neurosurgery 38 : 1036-1039, 1996   DOI   ScienceOn
4 Hochberg FH, Miller DC : Primary central nervous system lymphoma. J Neurosurg 68 : 835-853, 1988   DOI   PUBMED
5 Corry J, Smith JG, Wirth A, Quong G, Liew KH : Primary central nervous system lymphoma : age and performance status are more important than treatment modality. Int J Radiat Oncol Biol Phys 41 : 615-620, 1998   DOI   ScienceOn
6 Chamberlain MC, Kormanik PA : AIDS-related central nervous system lymphomas. J Neurooncol 43 : 269-276, 1999   DOI   ScienceOn
7 Tomlinson FH, Kurtin PJ, Suman VJ, Scheithauer BW, Fallon JR, Kelly PJ, et al : Primary intracerebral malignant lymphoma : a clinicopathological study of 89 patients. J Neurosurg 82 : 558-566, 1995   DOI   PUBMED   ScienceOn
8 Lee YY, Bruner JM, Van Tassell P, Libshitz HI : Primary central nervous system lymphoma : CT and pathologic correlation. AJR Am J Roentgenol 147 : 747-752, 1986   DOI   PUBMED   ScienceOn
9 Guzman R, Barth A, Lovblad KO, El-Koussy M, Weis J, Schroth G, et al : Use of diffusion-weighted magnetic resonance imaging in differentiating purulent brain processes from cystic brain tumors. J Neurosurg 97 : 1101-1107, 2002   DOI   ScienceOn
10 Lee CH, Lee JK, Kwun BD : Primary central nervous system lymphom a: a report of 33 cases. J Korean Neurosurg Soc 28 : 547-555, 1999
11 Johnson MD, Kinney MC, Scheithauer BW, Briley RJ, Hamilton K, McPherson WF, et al : Primary intracerebral Hodgkin's disease mimicking meningioma : case report. Neurosurgery 47 : 454-457, 2000   DOI   ScienceOn
12 Eby NL, Grufferman S, Flannelly CM, Schold SC Jr, Vogel FS, Burger PC : Increasing incidence of primary brain lymphoma in the US. Cancer 62 : 2461-2465, 1988   DOI   PUBMED   ScienceOn
13 Hiraga S, Arita N, Ohnishi T, Kohmura E, Yamamoto K, Oku Y, et al : Rapid infusion of high-dose methotrexate resulting in enhanced penetration into cerebrospinal fluid and intensified tumor response in primary central nervous system lymphomas. J Neurosurg 91 : 221- 230, 1999   DOI   ScienceOn
14 Glass J, Gruber ML, Cher L, Hochberg FH : Preirradiation methotrexate chemotherapy of primary central nervous system lymphoma : long-term outcome. J Neurosurg 81 : 188-195, 1994   DOI   ScienceOn