Environmental Chemical-Dioxin Impacts on Biological Systems: A Review |
Vo, Thuy Thi Bich
(Institute of Genome Research, Vietnam Academy of Science and Technology)
Le, Binh Thi Nguyen (Institute of Genome Research, Vietnam Academy of Science and Technology) Nong, Hai Van (Institute of Genome Research, Vietnam Academy of Science and Technology) Yang, Hyun (Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University) Jeung, Eui-Bae (Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University) |
1 | Costa LG. 2007. Contaminants in fish: risk-benefit considerations. Arh. Hig. Rada. Toksikol. 58(3):367-374. |
2 | Crofton KM, Craft ES, Hedge JM, Gennings C, Simmons JE, Carchman RA, Carter Jr. WH and DeVito MJ. 2005. Thyroid-hormone-disrupting chemicals: evidence for dose-dependent additivity or synergism. Environ. Health. Perspect.113(11):1549-1554. DOI |
3 | Donato F and Zani C. 2010. Chronic exposure to organochlorine compounds and health effects in adults: diabetes and thyroid diseases. Ann. Ig. 22(3):185-198. |
4 | da Rosa JS, Freitas-Silva O, Pacheco S, de Oliveira Godoy RL and de Rezende CM. 2012. LC-MS based screening and targeted profiling methods for complex plant: coffee a case study. Curr. Drug.Metab. 13(9):1244-1250. DOI |
5 | Dere E, Lo R, Celius T, Matthews J and Zacharewski TR. 2011. Integration of genome-wide computation DRE search, AhR ChIP-chip and gene expression analyses of TCDDelicited responses in the mouse liver. BMC. Genomics. 12:365. DOI |
6 | Ding T, McConaha M, Boyd KL, Osteen KG and Bruner-Tran KL. 2011. Developmental dioxin exposure of either parent is associated with an increased risk of preterm birth in adult mice. Reprod. Toxicol. 31(3):351-358. DOI |
7 | Faroon O, Jones D and de Rosa C. 2000. Effects of polychlorinated biphenyls on the nervous system. Toxicol. Ind.Health. 16(7-8):305-333. DOI |
8 | Feeley M and Brouwer A. 2000. Health risks to infants from exposure to PCBs, PCDDs and PCDFs. Food. Addit. Contam. 17(4):325-333. DOI |
9 | Fracchiolla NS, Todoerti K, Bertazzi PA, Servida F, Corradini P, Carniti C, Colombi A, Cecilia PA and Neri AD. 2011. Dioxin exposure of human CD34+ hemopoietic cells induces gene expression modulation that recapitulates its in vivo clinical and biological effects. Toxicology. 283(1):18-23. DOI |
10 | Fried KW, Guo GL, Esterly N, Kong B and Rozman KK. 2010. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) reverses hyperglycemia in a type II diabetes mellitus rat model by a mechanism unrelated to PPAR gamma. Drug. Chem. Toxicol.33(3):261-268. DOI |
11 | Gray LE, Wolf C, Mann P and Ostby JS. 1997. In utero exposure to low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin alters reproductive development of female Long Evans hooded rat offspring. Toxicol. Appl. Pharmacol. 146(2):237-244. DOI |
12 | Ganguly A and Shields CL. 2010. Differential gene expression profile of retinoblastoma compared to normal retina. Mol.Vis. 16: 1292-1303. |
13 | Gierthy JF, Bennett JA, Bradley LM and Cutler DS. 1993. Correlation of in vitro and in vivo growth suppression of MCF-7 human breast cancer by 2,3,7,8-tetrachlorodibenzop-dioxin. Cancer. Res. 53(13):3149-3153. |
14 | Gray LE and Ostby JS. 1995. In utero 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters reproductive morphology and function in female rat offspring. Toxicol. Appl. Pharmacol. 133(2):285-294. DOI |
15 | Gu YZ, Hogenesch JB and Bradfield CA. 2000. The PAS superfamily: sensors of environmental and developmental signals. Annu. Rev. Pharmacol. Toxicol. 40:519-561. DOI |
16 | Gueguen M, Amiard JC, Arnich N, Badot PM, Claisse D, Guerin T and Vernoux JP. 2011. Shellfish and residual chemical contaminants: hazards, monitoring, and health risk assessment along French coasts. Rev. Environ. Contam. Toxicol. 213:55-111. |
17 | Hall RH. 1992. A new threat to public health: organochlorines and food. Nutr. Health. 8(1):33-43. DOI |
18 | Helander B, Olsson A, Bignert A, Asplund L and Litzen K. 2002. The role of DDE, PCB, coplanar PCB and eggshell parameters for reproduction in the white-tailed sea eagle (Haliaeetus albicilla) in Sweden. Ambio. 31(5):386-403. |
19 | Hsu EL, Yoon D, Choi HH, Wang F, Taylor RT, Chen N, Zhang R and Hankinson O. 2007. A proposed mechanism for the protective effect of dioxin against breast cancer. Toxicol. Sci. 98(2):436-444. DOI |
20 | Kimbrough RD, Krouskas CA, Carson ML, Long TF, Bevan C and Tardiff RG. 2010. Human uptake of persistent chemicals from contaminated soil: PCDD/Fs and PCBs. Regul. Toxicol. Pharmacol. 57(1):43-54. DOI |
21 | Hutt KJ, Shi Z, Albertini DF and Petroff BK. 2008. The environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts morphogenesis of the rat pre-implantation embryo. BMC. Dev. Biol. 8:1. DOI |
22 | Jennen D, Ruiz-Aracama A, Magkoufopoulou C, Peijnenburg A, Lommen A, van Delft J and Kleinjans J. 2011. Integrating transcriptomics and metabonomics to unravel modesof-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells. BMC. Syst. Biol. 5:139. DOI |
23 | Kimbrough RD and Krouskas CA. 2001. Polychlorinated biphenyls, dibenzo-p-dioxins, and dibenzofurans and birth weight and immune and thyroid function in children. Regul. Toxicol. Pharmacol. 34(1):42-52. DOI |
24 | King-Heiden TC, Mehta V, Xiong KM, Lanham KA, Antkiewicz DS, Ganser A, Heideman W and Peterson RE. 2012. Reproductive and developmental toxicity of dioxin in fish. Mol. Cell. Endocrinol. 354(1-2):121-138. DOI |
25 | Koga T, Ishida T, Takeda T, Ishii Y, Uchi H, Tsukimori K, Yamamoto M, Himeno M, Furue M and Yamada H. 2012. Restoration of dioxin-induced damage to fetal steroidogenesis and gonadotropin formation by maternal co-treatment with alpha-lipoic acid. PLoS. One. 7(7):e40322. DOI |
26 | Kopf PG and Walker MK. 2009. Overview of developmental heart defects by dioxins, PCBs, and pesticides. J. Environ. Sci. Health. C. Environ. Carcinog. Ecotoxicol. Rev. 27(4):276-285. DOI |
27 | Kurokawa Y and Inoue T. 1998. Risk assessment of dioxins and the effect as the endocrine disrupters. Kokuritsu. Iyakuhin. Shokuhin. Eisei. Kenkyusho. Hokoku. (116):1-12. |
28 | Korkalainen M, Tuomisto J and Pohjanvirta R. 2001. The AH receptor of the most dioxin-sensitive species, guinea pig, is highly homologous to the human AH receptor. Biochem. Biophys. Res. Commun. 285(5):1121-1129. DOI |
29 | Kumar S. 2011. Occupational, environmental and lifestyle factors associated with spontaneous abortion. Reprod. Sci. 18(10):915-930. DOI |
30 | Kurita H, Yoshioka W, Nishimura N, Kubota N, Kadowaki T and Tohyama C. 2009. Aryl hydrocarbon receptor-mediated effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on glucose-stimulated insulin secretion in mice. J. Appl. Toxicol. 29(8):689-694. DOI |
31 | Lahvis GP and Bradfield CA. 1998. Ahr null alleles: distinctive or different?. Biochem. Pharmacol. 56(7):781-787. DOI |
32 | Langer P. 2008. Persistent organochlorinated pollutants (PCB, DDE, HCB, dioxins, furans) and the thyroid. Endocr. Regul. 42(2-3):79-104. |
33 | Lee DH, Jacobs DR and Porta M. 2007. Association of serum concentrations of persistent organic pollutants with the prevalence of learning disability and attention deficit disorder. J. Epidemiol. Community.Health. 61(7):591-596. DOI |
34 | Li B, Liu HY, Dai LJ, Lu JC, Yang ZM and Huang L. 2006. The early embryo loss caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin may be related to the accumulation of this compound in the uterus. Reprod. Toxicol. 21(3):301-306. DOI |
35 | Lin TM, Rasmussen NT, Moore RW, Albrecht RM and Peterson RE. 2003. Region-specific inhibition of prostatic epithelial bud formation in the urogenital sinus of C57BL/6 mice exposed in utero to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 76(1):171-181. DOI |
36 | Lo R and Matthews J. 2013. The aryl hydrocarbon receptor and estrogen receptor alpha differentially modulate nuclear factor erythroid-2-related factor 2 transactivation in MCF-7 breast cancer cells. Toxicol. Appl. Pharmacol. 270(2):139-148. DOI |
37 | Lind L. LPM. 2012. Can persistent organic pollutants and plastic-associated chemicals cause cardiovascular disease?. J. Intern. Med. 271(6):537-553. DOI |
38 | Lindsey S and Papoutsakis ET. 2012. The evolving role of the aryl hydrocarbon receptor (AHR) in the normophysiology of hematopoiesis. Stem. Cell. Rev. 8(4):1223-1235. DOI |
39 | Lo R and Matthews J. 2012. High-resolution genome-wide mapping of AHR and ARNT binding sites by ChIP-Seq. Toxicol. Sci. 130(2):349-361. DOI |
40 | Long M and Bonefeld-Jorgensen EC. 2012. Dioxin-like activity in environmental and human samples from Greenland and Denmark. Chemosphere. 89(8):919-928. DOI |
41 | Lundqvist C, Zuurbier M, Leijs M, Johansson C, Ceccatelli S, Saunders M, Schoeters G, ten Tusscher G and Koppe JG. 2006. The effects of PCBs and dioxins on child health. Acta. Paediatr. Suppl. 95(453):55-64. |
42 | Magre S, Rebourcet D, Ishaq M, Wargnier R, Debard C, Meugnier E, Vidal H, Cohen-Tannoudji J and Le Magueresse-Battistoni B. 2012. Gender differences in transcriptional signature of developing rat testes and ovaries following embryonic exposure to 2,3,7,8-TCDD. PLoS. One.7(7):e40306. DOI |
43 | Mann PC. 1997. Selected lesions of dioxin in laboratory rodents. Toxicol. Pathol. 25(1):72-79. DOI |
44 | Marinkovic N, Pasalic D, Ferencak G, Grskovic B and Stavljenic RA. 2010. Dioxins and human toxicity. Arh. Hig. Rada. Toksikol. 61(4):445-453. |
45 | Muller JH, Papke OC, Ball MC andMarschner H. 2000. Preliminary assessment of environmental impacts related to spraying of agent orange herbicide during the viet nam war. Chemosphere. 29:2175-2181. |
46 | Mitsui T, Taniguchi N, Kawasaki N, Kagami Y and Arita J. 2011. Fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin induces expression of the chemokine genes Cxcl4 and Cxcl7 in the perinatal mouse brain. J. Appl. Toxicol. 31(3):279-284. DOI |
47 | Monteiro P, Gilot D, Le Ferrec E, Rauch C, Lagadic-Gossmann D and Fardel O. 2008. Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway. Mol. Pharmacol.73(3):769-777. |
48 | Moran FM, Hendrickx AG, Shideler S, Overstreet JW, Watkins SM and Lasley BL. 2004. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on fatty acid availability and neural tube formation in cynomolgus macaque, Macaca fascicularis. Birth.Defects. Res. B. Dev. Reprod. Toxicol. 71(1):37-46. DOI |
49 | Munoz B and Albores A. 2010. The role of molecular biology in the biomonitoring of human exposure to chemicals. Int. J. Mol. Sci. 11(11):4511-4525. DOI |
50 | Murray FJ, Smith FA, Nitschke KD, Humiston CG, Kociba RJ and Schwetz BA. 1979. Three-generation reproduction study of rats given 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the diet. Toxicol. Appl. Pharmacol. 50(2):241-252. DOI |
51 | Nakajima S, Saijo Y, Kato S, Sasaki S, Uno A, Kanagami N, Hirakawa H, Hori T, Tobiishi K, Todaka T, Nakamura Y, Yanagiya S, Sengoku Y, Iida T, Sata F and Kishi R. 2006. Effects of prenatal exposure to polychlorinated biphenyls and dioxins on mental and motor development in Japanese children at 6 months of age. Environ. Health. Perspect. 114(5):773-778. |
52 | Pelclova D, Prazny M, Skrha J, Fenclova Z, Kalousova M, Urban P, Navratil T, Senholdova Z and Smerhovsky Z. 2007. 2,3,7,8-TCDD exposure, endothelial dysfunction and impaired microvascular reactivity. Hum. Exp. Toxicol. 26(9): 705-713. DOI |
53 | Needham LL, Barr DB, Caudill SP, Pirkle JL, Turner WE, Osterloh J, Jones RL and Sampson EJ. 2005. Concentrations of environmental chemicals associated with neurodevelopmental effects in U.S. population. Neurotoxicology 26(4):531-545. DOI |
54 | Nie M, Blankenship AL and Giesy JP. 2001. Interactions between aryl hydrocarbon receptor (AhR) and hypoxia signaling pathways. Environ. Toxicol. Pharmacol. 10(1-2):17-27. DOI |
55 | Papaleo B, Caporossi L, De Rosa M, Chiovato L, Ferrari M, Imbriani M, Signorini S and Pera A. 2004. Occupational exposure to endocrine disruptors: state of the art. G. Ital. Med. Lav. Ergon. 26(3):171-179. |
56 | Patrick L. 2009. Thyroid disruption: mechanism and clinical implications in human health. Altern. Med. Rev. 14(4):326- 346. |
57 | Pelclova D, Fenclova Z, Urban P, Ridzon P, Preiss J, Kupka K, Malik J, Dubska Z and Navratil T. 2009. Chronic health impairment due to 2,3,7,8-tetrachloro-dibenzo-p-dioxin exposure. Neuro. Endocrinol. Lett. 30 Suppl 1:219-224. |
58 | Phillips KP and Tanphaichitr N. 2008. Human exposure to endocrine disrupters and semen quality. J. Toxicol. Environ. Health. B. Crit. Rev. 11(3-4):188-220. DOI |
59 | Pohjanvirta R and Tuomisto J. 1994. Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models. Pharmacol. Rev. 46(4):483-549. |
60 | Peters AK, Sanderson JT, Bergman A and van den Berg M. 2006. Antagonism of TCDD-induced ethoxyresorufin-Odeethylation activity by polybrominated diphenyl ethers (PBDEs) in primary cynomolgus monkey (Macaca fascicularis) hepatocytes. Toxicol. Lett. 164(2):123-132. |
61 | Pohjanvirta R, Viluksela M, Tuomisto JT, Unkila M, Karasinska J, Franc MA, Holowenko M, Giannone JV, Harper PA, Tuomisto J and Okey AB. 1999. Physicochemical differences in the AH receptors of the most TCDD-susceptible and the most TCDD-resistant rat strains. Toxicol. Appl. Pharmacol. 155(1):82-95. DOI |
62 | Pohl HR and Hibbs BF. 1996. Breast-feeding exposure of infants to environmental contaminants- a public health risk assessment viewpoint: chlorinated dibenzodioxins and chlorinated dibenzofurans. Toxicol. Ind. Health. 12(5):593-611. DOI |
63 | Puga A, Barnes SJ, Chang C, Zhu H, Nephew KP, Khan SA and Shertzer HG. 2000. Activation of transcription factors activator protein-1 and nuclear factor-kappaB by 2,3,7,8- tetrachlorodibenzo-p-dioxin. Biochem. Pharmacol. 59(8):997- 1005. DOI |
64 | Puga A, Barnes SJ, Dalton TP, Chang C, Knudsen ES and Maier MA. 2000. Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest. J. Biol. Chem. 275(4):2943-2950. DOI |
65 | Radikova Z, Tajtakova M, Kocan A, Trnovec T, Sebokova E, Klimes I and Langer P. 2008. Possible effects of environmental nitrates and toxic organochlorines on human thyroid in highly polluted areas in Slovakia. Thyroid. 18(3):353- 362. DOI |
66 | Ray SS and Swanson HI. 2003. Alteration of keratinocyte differentiation and senescence by the tumor promoter dioxin. Toxicol. Appl. Pharmacol. 192(2):131-145. DOI |
67 | Revich BA and Shelepchikov AA. 2008. Environmental contamination with permanent organic pollutants and human health. Gig. Sanit. (4):26-32. |
68 | Roy JR, Chakraborty S and Chakraborty TR. 2009. Estrogenlike endocrine disrupting chemicals affecting puberty in humans- a review. Med. Sci. Monit. 15(6):RA137-145. |
69 | Sanchez-Martin FJ, Fernandez-Salguero PM and Merino JM. 2011. Aryl hydrocarbon receptor-dependent induction of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in cerebellar granule cells from mouse. J. Neurochem. 118(1):153- 162. DOI |
70 | Rier S and Foster WG. 2002. Environmental dioxins and endometriosis. Toxicol. Sci. 70(2):161-170. DOI |
71 | Ruby CE, Funatake CJ and Kerkvliet NI. 2005. 2,3,7,8 Tetrachlorodibenzo- p-dioxin (TCDD) directly enhances the maturation and apoptosis of dendritic cells In Vitro. J. Immunotoxicol. 1(3):159-166. DOI |
72 | Sharpe RM. 2010. Environmental/lifestyle effects on spermatogenesis. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 365(1546): 1697-1712. DOI |
73 | Sato S, Shirakawa H, Tomita S, Ohsaki Y, Haketa K, Tooi O, Santo N, Tohkin M, Furukawa Y, Gonzalez FJ and Komai M. 2008. Low-dose dioxins alter gene expression related to cholesterol biosynthesis, lipogenesis, and glucose metabolism through the aryl hydrocarbon receptor-mediated pathway in mouse liver. Toxicol. Appl. Pharmacol. 229(1):10-19 DOI |
74 | Schug TT, Janesick A, Blumberg B and Heindel JJ. 2011. Endocrine disrupting chemicals and disease susceptibility. J. Steroid. Biochem. Mol. Biol. 127(3-5):204-215. DOI |
75 | Sechman A, Hrabia A, Lis MW and Niedziolka J. 2011. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on steroid concentrations in blood and gonads of chicken embryo. Toxicol. Lett. 205(2):190-195. DOI |
76 | Shibamoto T, Yasuhara A and Katami T. 2007. Dioxin formation from waste incineration. Rev. Environ. Contam. Toxicol. 190:1-41. |
77 | Spencer DL, Masten SA, Lanier KM, Yang X, Grassman JA, Miller CR, Sutter TR, Lucier GW and Walker NJ. 1999. Quantitative analysis of constitutive and 2,3,7,8-tetrachlorodibenzo- p-dioxin-induced cytochrome P450 1B1 expression in human lymphocytes. Cancer. Epidemiol. Biomarkers. Prev. 8(2):139-146. |
78 | Smith KJ, Murray IA, Tanos R, Tellew J, Boitano AE, Bisson WH, Kolluri SK, Cooke MP and Perdew GH. 2011. Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism. J. Pharmacol. Exp. Ther. 338(1):318-327. DOI |
79 | Sikka SC and Wang R. 2008. Endocrine disruptors and estrogenic effects on male reproductive axis. Asian. J. Androl. 10(1):134-145. DOI |
80 | Slowinska M, Koter-Michalak M and Bukowska B. 2011. The effect of dioxins on the human organism-epidemiological studies. Med. Pr. 62(6):643-652. |
81 | Sweeney MH, Calvert GM, Egeland GA, Fingerhut MA, Halperin WE and LA. P. 1997-1998. Review and update of the results of the NIOSH medical study of workers exposed to chemicals contaminated with 2,3,7,8-tetrachlorodibenzodioxin. Teratog. Carcinog. Mutagen. 17(4-5):241-247. |
82 | Suzuki G, Takigami H, Nose K, Takahashi S, Asari M and Sakai S. 2007. Dioxin-like and transthyretin-binding compounds in indoor dusts collected from Japan: average daily dose and possible implications for children. Environ. Sci. Technol. 41(4):1487-1493. DOI |
83 | Swedenborg E and Pongratz I. 2010. AhR and ARNT modulate ER signaling. Toxicology 268(3):132-138. DOI |
84 | Sweeney MH and Mocarelli P. 2000. Human health effects after exposure to 2,3,7,8-TCDD. Food. Addit. Contam. 17(4): 303-316. DOI |
85 | TakedaT, Taura J, Fujii M, Koga T, Ishii Y and Yamada H. 2011. The effect of maternal exposure to dioxin on fetal steroidogenesis in the steroidogenic organs. Fukuoka. Igaku. Zasshi. 102(4):159-166. |
86 | Tsang H, Cheung TY, Kodithuwakku SP, Chai J, Yeung WS, Wong CK and Lee KF. 2012. 2,3,7,8-Tetrachlorodibenzop- dioxin (TCDD) suppresses spheroids attachment on endometrial epithelial cells through the down-regulation of the Wnt-signaling pathway. Reprod. Toxicol. 33(1):60-66. DOI |
87 | Thackaberry EA, Jiang Z, Johnson CD, Ramos KS and Walker MK.2005. Toxicogenomic profile of 2,3,7,8-tetrachlorodibenzo- p-dioxin in the murine fetal heart: modulation of cell cycle and extracellular matrix genes. Toxicol. Sci. 88(1): 231-241. DOI |
88 | Tsuchiya M, Imai H, Nakao H, Kuroda Y and Katoh T. 2003. Potential links between endocrine disrupting compounds and endometriosis. J. UOEH. 25(3):307-316. |
89 | Tian Y, Ke S, Denison MS, Rabson AB and Gallo MA. 1999. Ah receptor and NF-kappa B interactions, a potential mechanism for dioxin toxicity. J. Biol. Chem. 274(1):510-515. DOI |
90 | Tilson HA and Kodavanti PR. 1997. Neurochemical effects of polychlorinated biphenyls: an overview and identification of research needs. Neurotoxicology 18(3):727-743. |
91 | Van Loveren H, Vos J, Putman E and Piersma A. 2003. Immunotoxicological consequences of perinatal chemical exposures: a plea for inclusion of immune parameters in reproduction studies. Toxicology 185(3):185-191. DOI |
92 | Tuomisto J and Tuomisto JT. 2012. Is the fear of dioxin cancer more harmful than dioxin?. Toxicol. Lett. 210(3): 338-344. DOI |
93 | Uemura H. 2012. Associations of exposure to dioxins and polychlorinated biphenyls with diabetes: based on epidemiological findings. Nihon. Eiseigaku. Zasshi. 67(3):363-374. DOI |
94 | Van Birgelen AP and Van den BM. 2000. Toxicokinetics. Food. Addit. Contam. 17(4):267-273. DOI |
95 | Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR, Lee DH, Shioda T, Soto AM, vom Saal FS, Welshons WV, Zoeller RT and Myers JP. 2012. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr. Rev. 33(3):378-455. DOI |
96 | Watanabe S, Kitamura K and Nagahashi M. 1999. Effects of dioxins on human health: a review. J. Epidemiol. 9(1):1-13. |
97 | Weiss J, Papke O, Bignert A, Jensen S, Greyerz E, Agostoni C, Besana R, Riva E, Giovannini M and Zetterstrom R. 2003. Concentrations of dioxins and other organochlorines (PCBs, DDTs, HCHs) in human milk from Seveso, Milan and a Lombardian rural area in Italy: a study performed 25 years after the heavy dioxin exposure in Seveso. Acta. Paediatr. 92(4):467-472. |
98 | Whitlock JP. 1987. The regulation of gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Pharmacol. Rev. 39(2): 147-161. |
99 | Wens B, De Boever P, Maes M, Hollanders K and Schoeters G. 2011. Transcriptomics identifies differences between ultrapure non-dioxin-like polychlorinated biphenyls (PCBs) and dioxin-like PCB126 in cultured peripheral blood mononuclear cells. Toxicology 287(1-3):113-123. DOI |
100 | Yoshioka W, Peterson RE and Tohyama C. 2011. Molecular targets that link dioxin exposure to toxicity phenotypes. J. Steroid. Biochem. Mol. Biol. 127(1-2):96-101. DOI |
101 | Wolf CJ, Ostby JS and Gray LE. 1999. Gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) severely alters reproductive function of female hamster offspring. Toxicol. Sci. 51(2):259-264. DOI |
102 | Wu Q, Zhou ZJ and Ohsako S. 2006. Effect of environmental contaminants on DNA methyltransferase activity of mouse preimplantation embryos. Wei. Sheng. Yan. Jiu. 35(1):30- 32. |
103 | Aragon AC, Kopf PG, Campen MJ, Huwe JK and Walker MK. 2008. In utero and lactational 2,3,7,8-tetrachlorodibenzo- p-dioxin exposure: effects on fetal and adult cardiac gene expression and adult cardiac and renal morphology. Toxicol. Sci. 101(2):321-330. DOI |
104 | Bao LJ, Maruya KA, Snyder SA and Zeng EY. 2011. China's water pollution by persistent organic pollutants. Environ. Pollut. 163:100-108. |
105 | Ahn NS, Hu H, Park JS, Kim JS, An S, Kong G, Aruoma OI, Lee YS and Kang KS. 2005. Molecular mechanisms of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced inverted U-shaped dose responsiveness in anchorage independent growth and cell proliferation of human breast epithelial cells with stem cell characteristics. Mutat. Res. 579(1-2):189-199. DOI |
106 | Alonso-Magdalena P, Quesada I and Nadal A. 2011. Endocrine disruptors in the etiology of type 2 diabetes mellitus. Nat. Rev. Endocrinol. 7(6):346-353. DOI |
107 | Arima A, Kato H, Ise R, Ooshima Y, Inoue A, Muneoka A, Kamimura S, Fukusato T, Kubota S, Sumida H and Yasuda M. 2010. In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces disruption of glands of the prostate and fibrosis in rhesus monkeys. Reprod. Toxicol. 29(3):317-322. DOI |
108 | Ballester M, Dehan P, Beliard A, Brichant G and Nisolle M. 2012. Role of genetic and environmental factors in the development of endometriosis. Rev. Med. Liege. 67(5-6):374-380. |
109 | Birnbaum LS and Cummings AM. 2002. Dioxins and endometriosis: a plausible hypothesis. Environ. Health Perspect. 110(1):15-21. DOI |
110 | Birnbaum LS and Tuomisto J. 2000. Non-carcinogenic effects of TCDD in animals. Food Addit. Contam. 17(4):275-288. DOI |
111 | Birnbaum LS, Staskal DF and Diliberto JJ. 2003. Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs). Environ. Int. 29(6):855-860. DOI |
112 | Bjerke DL, Sommer RJ, Moore RW and Peterson RE. 1994. Effects of in utero and lactational 2,3,7,8-tetrachlorodibenzo- p-dioxin exposure on responsiveness of the male rat reproductive system to testosterone stimulation in adulthood. Toxicol. Appl. Pharmacol. 127(2):250-257. DOI |
113 | Boas M, Main KM and Feldt-Rasmussen U. 2009. Environmental chemicals and thyroid function: an update. Curr. Opin. Endocrinol. Diabetes. Obes. 16(5):385-391. DOI |
114 | Bruner-Tran KL and Osteen KG. 2010. Dioxin-like PCBs and endometriosis. Syst. Biol. Reprod. Med. 56(2):132-146. DOI |
115 | Bonefeld-Jorgensen EC. 2010. Biomonitoring in Greenland:human biomarkers of exposure and effects - a short review. Rural. Remote. Health. 10(2):1362. |
116 | Borchers A, Teuber SS, Keen CL and Gershwin ME. 2010. Food safety. Clin. Rev. Allergy. Immunol. 39(2):95-141. DOI |
117 | Boverhof DR, Burgoon LD, Tashiro C, Sharratt B, Chittim B,Harkema JR, Mendrick DL and Zacharewski TR. 2006. Comparative toxicogenomic analysis of the hepatotoxic effects of TCDD in Sprague Dawley rats and C57BL/6 mice. Toxicol. Sci. 94(2):398-416. DOI |
118 | Bushkin-Bedient S and Carpenter DO. 2010. Benefits versus risks associated with consumption of fish and other seafood. Rev. Environ. Health. 25(3):161-191. |
119 | Carpenter DO. 2006. Polychlorinated biphenyls (PCBs):routes of exposure and effects on human health. Rev. Environ. Health. 21(1):1-23. DOI |
120 | Carpi D, Korkalainen M, Airoldi L, Fanelli R, Hakansson H, Muhonen V, Tuukkanen J, Viluksela M and Pastorelli R. 2009. Dioxin-sensitive proteins in differentiating osteoblasts:effects on bone formation in vitro. Toxicol. Sci. 108(2):330-343. DOI |