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Acetylcholinesterase Inhibition and Behavioral Changes of Crucian carp (Carassius auratus) Exposed to the Waterborne Parathion  

Cho, Kyu-Seok (Department of Inland Fisheries Research Institute, Chung Cheong Buk-Do)
Park, Jong-Ho (Department of Environmental Engineering, Chung Ju National University)
Lee, Won-Ho (Department of Construction & Urban Engineering, Chung Ju National University)
Kang, Ju-Chan (Department or Aquatic Lire Medicine, Pukyong National University)
Publication Information
Journal of Korean Society on Water Environment / v.22, no.2, 2006 , pp. 364-369 More about this Journal
Abstract
The investigation of the Acetylcholinesterase (AChE) activity in tissues (brain, eye, muscle and serum) of crucian carp (Carassius auratus) exposed to the waterborne parathion was carried out for application as biomarker of organophosphate pesticides. The AChE activities were significantly inhibited in the experimental organs of C. auratus treated ${\geq}63{\mu}g/L$ of concentrations of parathion. The AChE activity of C. auratus was significantly reduced in response to brain (79.1~92.4%), eye (76.0~91.5%), muscle (89.7~97.6%) and serum (68.9~78.0%) after 30 days exposure. No significant mortality occurred during the experiment duration but behavioral changes occurred in the carp after exposure to the parathion were erratic swimming and convulsions. The anomaly in the carp exposed to parathion were observed in the form of scoliosis. The use of AChE activity and other adverse responses of the carp might be use as a reliable monitoring tool to detect parathion in aquatic ecosystem which might produce significant population changes.
Keywords
Acetylcholinesterase; Carassius auratus; Parathion; Scoliosis; Sublethal concentration;
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