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http://dx.doi.org/10.5762/KAIS.2020.21.11.273

Meta-Analysis on the Effect of Serum Lipids Levels in Silkworm and Silkworm Pupae  

Kim, Eun-Joo (Department of Alternative Medicine Graduate School Kyonggi University)
Lee, So-Young (Department of Alternative Medicine Graduate School Kyonggi University)
Kim, Ae-Jung (Department of Alternative Medicine Graduate School Kyonggi University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.21, no.11, 2020 , pp. 273-282 More about this Journal
Abstract
This study analyzed the physiological effects of silkworms and silkworm pupae on the reduction of serum lipid levels. Research data specific to silkworms and their pupae published over the last 10 years were collected and analyzed. A large effect size of 0.852 was observed in the overall results and the range of 95% confidence intervals was 0.662 to 0.999. The Q value was 23.264, the Higgin's I2 value was 92.217, indicating that each study was heterogeneous. There was no publication bias, as the corrected observed number of statistically significant effect sizes and the expected number of statistically significant effect sizes were both 0.654. The silkworm study showed a large effect size with respect to blood sugar and blood lipid reduction at 0.801 and 0.948, respectively, and LDL-cholesterol reduction at 1.371, showing a very large effect size. Aspartate transaminase / glutamic oxaloacetic transaminase (AST/GOT) was 0.768, alanine transaminase /glutamate-pyruvate transaminase (ALT/GPT) was 0.788, which was a medium effect size. The experiment period had a very large effect size of 1.170 for five to eight weeks and 1.020 for an intake of 1 to 50 mg/kg. The silkworm pupae had a large effect size of 0.991 and 0.951, respectively on blood lipids and total cholesterol reduction. The experimental period showed a very large effect size at 1.103 for more than nine weeks, and the intake showed a large effect size at 0.855 for 5001 mg/kg.
Keywords
Silkworm; Silkworm Pupae; Insect food; Meta-analysis; Effect size;
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