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http://dx.doi.org/10.5762/KAIS.2019.20.7.119

The Effects of Task oriented Training on Motor and Cognitive Function in Alzheimer's Dementia Rat  

Lim, Gun-Hong (Department of Physical Therapy, Dongshin University)
Lee, Hong gyun (Department of Physical Therapy, Dongshin University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.20, no.7, 2019 , pp. 119-126 More about this Journal
Abstract
This study was conducted to investigate the effects of task oriented training on motor and cognitive function recovery in rats with induced Alzheimer's dementia. Thirty Sprague-Dawley rats were randomly assigned to a control group (n=15) and an experimental group (n=15). Training was given three times a week, for 20 minutes a session for 4 weeks. The cognitive and motor functions of the rats were evaluated by an eight arm radial maze test and ladder rung walk test. The eight arm radial maze test showed significant differences between groups according to the time of day 14 and 28 (p<.001). The difference in measured values according to the timing of the two groups was significant (p<.001). Additionally, there was a significant difference between the time and the group interaction (p<.001). The ladder rung walk test showed significant differences between groups according to the time of day 14 and 28 (p<.001). The difference in the measured values according to the timing of the two groups was significant (p<.001), and there was a significant difference between the time and the group interaction (p<.001). As a result, task oriented training for Alzheimer's dementia rats was found to have a positive effect on recovery of motor and cognitive function.
Keywords
${\beta}-Amyloid$; Alzheimer's Dementia; Task Oriented Training; Motor Function; Cognitive Function;
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