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http://dx.doi.org/10.5762/KAIS.2017.18.5.667

Antibacterial Activity of Graviola extract to inhibit the Staphylococcus epidermidis  

Choi, Jong-Hwa (Interdisciplinary Program of Perfume and Cosmetics, Graduate School of Chonnam National University)
Ohk, Seung-Ho (Interdisciplinary Program of Perfume and Cosmetics, Graduate School of Chonnam National University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.18, no.5, 2017 , pp. 667-673 More about this Journal
Abstract
This study was carried out to verify the antimicrobial effect of Graviola leaves against pathogenic bacteria for the purpose of developing an antibacterial material. The extraction conditions of graviola leaves were $60^{\circ}C$, $80^{\circ}C$ and $98^{\circ}C$, and graviloa leaves werewater extracted at $60^{\circ}C$, $80^{\circ}C$ and $98^{\circ}C$.The extraction yields and extraction conditions were determined. The antimicrobial activity against S. epidermidis, S. aureus and E. coli TOP10 was evaluated by agar diffusion method. The extraction yields were 3.02%, 14.73% and 20.76% at $60^{\circ}C$, $80^{\circ}C$ and $98^{\circ}C$, respectively. The antimicrobial activity against S. epidermidis, S. aureus and E. coli TOP10 was found in S. epidermidis.In the samples extracted at $98^{\circ}C$, a clear zone of 13 mm was observed at 200 mg/mL and of 20 mm at 500 mg/mL. The MIC was 100 mg/mL. The higher the extraction temperature and concentration, the better was the growth inhibition effect. As a result, the natural antimicrobial activity contained in natural materials can solve the problem of resistance to antibiotics. It is considered that antimicrobial activity against S. epidermidis in skin is highly applicable to basic cosmetics and cosmetic materials.
Keywords
Antibacterial effect; Graviola; Minimum Inhibitory Concentration; S. epidermidis; Soursop;
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