Browse > Article
http://dx.doi.org/10.5762/KAIS.2017.18.11.433

Associations between pulmonary function disorders & Metabolic Syndrome: A Cross-Sectional Study Using Data from KNHANES 2008-2013  

Kang, Sun-Hee (Department of Medical Information Management, Kongju National University)
Boo, Yoo-Kyung (Department of Healthcare Management, Eulji University)
Ahn, Byung-Ki (Department of Health Care Management, WooSong University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.18, no.11, 2017 , pp. 433-444 More about this Journal
Abstract
This study was conducted to identify relationships between lung function disorders and Metabolic Syndrome(MetS) that have common comorbidities such as Cardio Vascular Diseases(CVD). According to the hypothesis that there may be a significant relationship between them, analyses were conducted to identify the proper management point for those diseases. Overall, 53,829 data were taken from KNHANES 2008-2013. Included data were PFT(Pulmonary Function Test) done and age over 40. All the 14 confounders applied, only 8,137 cases (M:3,951, F:4,186) were left. Low pulmonary function was divided into two categories, obstructive and restrictive patterns, based on the Global Initiative for Chronic Obstructive Lung Disease(GOLD) criteria, while MetS was defined based on the revised NCEP-ATPIII criteria. The relationships between those diseases were analyzed using logistic regression analysis. In addition, for the prevalence rate, cross-tab analysis were conducted. There were no significant relationships observed between obstructive lung disease and MetS, but a restrictive pattern had a meaningful relationship with MetS. Specifically, MetS showed a higher prevalence rate for both obstructive and restrictive pattern patients than the control group. Restrictive pattern patients showed a higher prevalence rate to MetS than obstructive patients. Overall, restrictive lung patterns showed a meaningful association with MetS, but not with obstructive patterns. Additionally, the prevalence rate of MetS among restrictive patients was higher than among obstructive patients.
Keywords
Cardiovascular disease; KNHANES; Metabolic Syndrome(MetS); Obesity; Obstructive lung disease; Prevalence Rate; Restrictive lung disease;
Citations & Related Records
Times Cited By KSCI : 4  (Citation Analysis)
연도 인용수 순위
1 L. Dave, S. Garde, O. A. Ansari, N. Shrivastava, V. K. Sharma, "A Study of association between metabolic syndrome and COPD", Journal of Evolution of Medical and Dental Sciences, vol. 3, no. 22, pp. 6183-6188, Jun. 2014. DOI: https://doi.org/10.14260/jds/2014/2720   DOI
2 K.B.H. Lam, R. E. Jordan, C. Q. Jiang, G. N. Thomas, M. R. Miller, W. S. Zhang, T. H. Lam, K. K. Cheng, P. Adab, "Airflow obstruction and metabolic syndrome: the Guangzhou Biobank Cohort Study", European Respiratory Journal vol. 35, no. 2, pp. 317-323, July. 2009. DOI: https://doi.org/10.1183/09031936.00024709   DOI
3 F. C. Hsiao, C. Z. Wu, S. C. Su, M. T. Sun, C. H. Hsieh, Y...J Hung, C.. T.He, D. Pei, "Baseline forced expiratory volume in the first second as an independent predictor of development of the metabolic syndrome", Metabolism Clinical and Experimental vol. 59, no. 6, pp. 848-853, Jun. 2010. DOI: https://doi.org/10.1016/j.metabol.2009.10.001   DOI
4 J. S. Rana,, M. A. Mittleman, J. Sheikh, F. B. Hu, J. E. Manson, G. A. Colditz, F. E. Speizer, R. G. Barr, C. A. Camargo, "Chronic obstructive pulmonary disease, asthma and risk of type 2 diabetes in women." Diabetes Care, vol. 27, no. 10, pp. 2478-84, Oct. 2004. DOI: https://doi.org/10.2337/diacare.27.10.2478   DOI
5 S. M. Grundy, J I. Cleeman, S. R. Daniels, K. A. Donato, R. H. Eckel, B. A. Franklin, D. J. Gordon, R. M. Krauss, P. J. Savage, S. C. Smith, J. A. Spertus and F. Costa, "Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement", Circulation, vol. 112, no. 17, pp. 2735-2752, Oct. 2005. DOI: http://doi.org/10.1161/CIRCULATIONAHA.105.169404   DOI
6 H. K. Kim, K. H. Choi, S. W. Lim, H. S. Rhee, "Development of Prediction Model for Prevalence of Metabolic Syndrome Using Data Mining: Korea National Health and Nutrition Examination Study" Journal of Digital Convergence, vol. 14, no. 2, pp. 325-33, Feb. 2016. DOI : https://doi.org/10.14400/JDC.2016.14.2.325   DOI
7 D. A. Lawlor, S. Ebrahim, G. D. Smith. "Associations of measures of lung function with insulin resistance and Type 2 diabetes: findings from the British Women's Heart and Health Study, Diabetologia 47, no. 2, pp. 195-203, Feb. 2004. DOI: https://doi.org/10.1007/s00125-003-1310-6   DOI
8 H. Watz, B. Waschki, A. Kirsten, K. C. Müller, G. Kretschmar, T. Meyer, O.Holz, H. Magnussen, "The Metabolic Syndrome in Patients With Chronic Bronchitis and COPD: Frequency and Associated Consequences for Systemic Inflammation and Physical Inactivity", Chest, vol. 136, no. 4, Oct. 2009. DOI: https://doi.org/10.1378/chest.09-0393   DOI
9 Y. S. Jo, S. M. Choi, J. W. Lee, Y. S. Park, S. M. Lee, J. J. Yim, C. G. Yoo, Y. W. Kim, S. K Han, C. H. Lee "The Relationship Between Chronic Obstructive Pulmonary Disease and Comorbidities: A Cross-Sectional Study Using Data from KNHANES 2010-2012", Respiratory Medicine, vol. 109, no. 1, Jan, 2015. DOI: http://dx.doi.org/10.1016/j.rmed.2014.10.015   DOI
10 H. C. Yeh, N. M. Punjabi, N. Y. Wang, J. S, Pankow, B. B. Duncan, C. E. Cox E. Selvin, F. L. Brancati, "Cross-Sectional and Prospective Study of Lung Function in Adults with Type 2 Diabetes: the Atherosclerosis Risk in Communities (ARIC) Study", Diabetes Care, vol. 31, pp. 741-6, Apr. 2008. DOI: https://doi.org/10.2337/dc07-1464   DOI
11 F. M. E. Franssen, D. E. O'Donnell, G. H. Goossens, E. E. Blaak, A. W. J. Schols, "Obesity and the lung: 5. Obesity and COPD", Thorax 63, no. 12, pp. 1110-1117, Apr. 2008. DOI: http://dx.doi.org/10.1136/thx.2007.086827   DOI
12 A. Tiengo, G. P. Fadini, A. Avogaro "The metabolic syndrome, diabetes and lung dysfunction", Diabetes & Metabolism, vol. 34. no. 5 pp. 447-454, Nov. 2008. DOI: http://dx.doi.org/10.1016/j.diabet.2008.08.001   DOI
13 COPD Guideline Revision Committee, COPD Guideline Revised 2014; The Korean Academy of Tuberculosis and Respiratory Diseases, Seoul, Korea, c2014[cited 2016 Aug. 23]Available from https://www.lungkorea.org/thesis/file/copd_slide_2014.pdf, (accessed Nov. 20, 2016)
14 Global Initiative for Chronic Obstructive Lung Disease.(GOLD): Teaching Slide Set, GOLD, [cited Jan. 2015] Available from: http://www.goldcopd.com (accessed Nov. 27, 2016)
15 G. M. Reaven, "Role of insulin resistance in human disease", Diabetes, vol. 37, pp. 1595-1607, Dec. 1988.   DOI
16 J. H. Chung, H. J. Hwang, C. H. Han, B. S. Son, D. H. Kim, M. S. Park, "Association between Sarcopenia and Metabolic Syndrome in Chronic Obstructive Pulmonary Disease: The Korea National Health and Nutrition Examination Survey (KNHANES) from 2008 to 2011", COPD: JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE Informa Healthcare USA, Inc. COPD, vol. 12, no. 1, pp. 82-89, Jun. 2014. DOI: https://doi.org/10.3109/15412555.2014.908835   DOI
17 S. K. Kim, J. C. Bae, J. H. Baek, J. H. Jee, K. Y. Hur, M. K. Lee, J. H. Kim, "Decline in lung function rather than baseline lung function is associated with the development of metabolic syndrome: A six-year longitudinal study", journals.plos.org/plosone/0174228, Mar. 2017. DOI: https://doi.org/10.1371/journal.pone.0174228   DOI
18 K. R. Park, Y. C. Cho, "Prevalence Rates of Risk Factors of Metabolic Syndrome, and Its Related with Obesity Indices Among the Health Checkup Examines," Journal of the Korea Academia- Industrial cooperation Society, vol. 17, no. 3, pp. 153-162, Mar. 2016. DOI : https://doi.org/10.5762/KAIS.2016.17.3.153   DOI
19 G. Fantuzzi, "Adipose tissue, adipokines, and inflammation", J Allergy Clin Immunol, vol. 115, no. 5, pp. 911-919, May. 2005. DOI: http://dx.doi.org/10.1016/j.jaci.2005.02.023   DOI
20 E. Kern, "Metabolic Syndrome and Systemic Inflammation in COPD", COPD: Journal of Chronic Obstructive Pulmonary Disease, vol. 8, no. 6, pp. 395-396, Dec. 2011. DOI: http://dx.doi.org/10.3109/15412555.2011.636554   DOI
21 P. Ranasinghe, Y. Mathangasinghe, R. Jayawardena, A. P. Hills and A. Misra, "Prevalence and trends of metabolic syndrome among adults in the asia-pacific region: a systematic review", BMC Public Health, vol. 17, no. 101, Jan. 2017. DOI: https://doi.org/10.1186/s12889-017-4041-1   DOI
22 H. J. Yoon, S. K. Lee, "The Incidence and Risk Factors of Metabolic Syndrome in Rural Area", Journal of the Korea Academia-Industrial cooperation Society, vol. 16, no. 6, pp. 3934-3943, Jun. 2015. DOI: https://doi.org/10.5762KAIS2015.16.6.3694   DOI
23 Y. C. Cho, I. S. Kwon, J. Y. Park, M. W Shin, "Prevalence of Metabolic Syndrome and Its Associated Factors among Health Checkup Examinees in a University Hospital", Journal of the Korea Academia-Industrial cooperation Society, vol. 13, no. 11, pp. 5317-5325, Nov. 2012. DOI: https://doi.org/10.5762KAIS2012.13.11.5317   DOI
24 S. H Landis, H. Muellerova,.D.M Mannino, A.M Menezes, M. K Han, Thys van der Molen, M. Ichinose, Z. Aisanov, Y. M. Oh, K. J Davis, "Continuing to Confront COPD International Patient Survey: methods, COPD prevalence, and disease burden in 2012-2013", International Journal of COPD, no. 9, pp. 597-611, Jun. 2014. DOI: http://dx.doi.org/10.2147/COPD.S61854   DOI
25 N. C. Lipovec, R.J. Beijers, B.V.D Borst, W. Doehner, M. Lainscak & Annemie M. W. J. Schols, "The Prevalence of Metabolic Syndrome In Chronic Obstructive Pulmonary Disease: A Systematic Review", journal COPD, Journal of Chronic Obstructive Pulmonary Disease, vol. 13, no. 3, PP 399-406, Feb. 2016. DOI: http://dx.doi.org/10.3109/15412555.2016.1140732   DOI
26 S. H. Beigh, S. Jain, "Prevalence of metabolic syndrome and gender differences", Bio Information, vol. 8, no. 13, pp. 613-616, Jul. 2012
27 Y. J. Paek, K. S. Jung, Y. I. Hwang, K. S. Lee, D. R. Lee, J. U. Lee, "Association between low pulmonary function and metabolic risk factors in Korean adults: the Korean National Health and Nutrition Survey", Metabolism Clinical and Experimental, vol. 59, no. 9, pp. 1300-1306, Sep. 2010. DOI: https://doi.org/10.1016/j.metabol.2009.12.005   DOI
28 D. M. Mannino, D. Thorn, A. Swensen, F. Holguin. "Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD", Eur Respir J, vol. 32, no. 4. pp. 962-969, Jun. 2008. DOI: https://doi.org/10.1183/09031936.00012408   DOI
29 L. M. G. Steuten, E. C. Creutzberg, H. J .M. Vrijhoef, E. F. Wouters, "COPD as a multicomponent disease: Inventory of dyspnoea, underweight, obesity and fat free mass depletion in primary care", Primary Care Respiratory Journal, vol. 15, no. 2, pp. 84-91, Apr. 2006. DOI: http://dx.doi.org/10.1016/j.pcrj.2005.09.001   DOI
30 E. S. FORD, T. J. Cunningham, C .I. Mercado, "Lung function and metabolic syndrome: Findings of National Health and Nutrition Examination Survey 2007-2010", Journal of Diabetes vol. 6, no. 6, pp. 603-613, Mar. 2014. DOI: https://doi.org/10.1111/1753-0407.12136   DOI
31 W. Y. Lin, C. A. Yao, H. C. Wang, K. C. Huang, "Impaired lung function is associated with obesity and metabolic syndrome in adults", Obesity vol. 14. no. 9, pp. 1654-1661, Sep. 2006. DOI: https://doi.org/10.1038/oby.2006.190   DOI
32 K. Nakajima, Y. Kubouchi, T. Muneyuki, M. Ebata, S. Eguchi, H. Munakata, Committee for the Diagnostic Criteria of Metabolic Syndrome, "A Possible Association Between Suspected Restrictive Pattern as Assessed by Ordinary Pulmonary Function Test and the Metabolic Syndrome", Chest, vol. 134, no. 4, pp. 712-718. Oct. 2008 DOI: https://doi.org/10.1378/chest.07-3003   DOI