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http://dx.doi.org/10.5762/KAIS.2015.16.6.3973

The Improvement Effects of β-Glucan on Adiposity and Serum Lipids Levels in High Fat Diet-Induced Obese Rats  

Hong, Kyung Hee (Dept. of Food Science and Nutrition, Dongseo University)
Kim, Hyun-Soon (Dept. of Conversing Technology, Graduate School of Venture, Hoseo University)
Jang, Ki-Hyo (Dept. of Food and Nutrition, Kangwon University)
Kang, Soon Ah (Dept. of Conversing Technology, Graduate School of Venture, Hoseo University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.16, no.6, 2015 , pp. 3973-3981 More about this Journal
Abstract
This study was aimed to investigate the effect of dietary ${\beta}$-glucan obtained from bacterial fermentation on the adiposity and serum lipids level in rats. Sprague-Dawley rats fed high fat diet for 6 weeks to induce obesity, and subsequently fed with 0% (high fat control group), 0.1% or 0.5% ${\beta}$-glucan supplemented high-fat diets (w/w) for another 5 weeks. For comparison, normal control groups fed AIN-76A diet. Supplemented with 0.1% ${\beta}$-glucan resulted in a significant reduction of high-fat induced peritoneal fat and visceral fat development by 16%, 19%, and 28%, respectively(P<0.05). Serum free fatty acid levels were reduced(by 19%), whereas the HDL cholesterol level was increased(by 50%) by 0.1% dietary ${\beta}$-glucan(P<0.05). In conclusion, dietary ${\beta}$-glucan reduced adiposity and improved serum lipids in obese rats fed high fat diet. The present study suggest that ${\beta}$-glucan supplementation to the diet is beneficial in suppressing diet-induced obesity and dyslipidemia.
Keywords
beta-Glucan; Fat mass; Leptin; Obesity; Serum lipid;
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