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http://dx.doi.org/10.5762/KAIS.2013.14.3.1294

Usefulness of contrast agent involving high gadolium content for myocardial viability assessment  

Choi, Kwan-Woo (Department of Radiology, Asan Medical Center)
Son, Soon-Yong (Department of Radiology, Asan Medical Center)
Kim, Tae-Hyung (Department of Radiological Science, Kangwon National University)
Han, Man-Seok (Department of Radiological Science, Kangwon National University)
Lee, Ju-Hee (Department of Radiology, Asan Medical Center)
Min, Jung-Whan (Department of Radiology, Shin-Gu University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.14, no.3, 2013 , pp. 1294-1300 More about this Journal
Abstract
The purpose of this study is to increase contrast to noise ratio(CNR) in myocardial viability test by using contrast agent which highly content gadolinium(1mmol/mL) maximizing diagnostic value. This research method that four hundred four patients were underwent the MRI scanning two hundred eighty four of them were injected commercial contrast media which have 0.5mmol/L and the rest of them were injected new contrast media(gadobutrol) which have 1mmol/mL of molarity to study the contrast difference depending on the molarity of the contrast agent signal intensities of normal ventricle and left ventricle were measured to compare and evaluate signal to noise ratio(SNR) and CNR of the images. As result, 1mmol/mL contrast agent showed higher SNR by 25.13% in myocardium and 30.74% in left ventricle. CNR was proved to be better in 1mmol/mL contrast agent by 31.29%. The results above were all statistically meaningful. Therefore, contrast agent contenting more gadolinium which was 1mmol/mL in this study, could more effectively shorten T1 relaxation time, increase the signal intensity and at the same time maximize CNR and diagnostic value. This study firstly report the usefulness of 1mmol/mL contrast agent in patients allegedly suffering cardiac diseases and it is considered to increase diagnostic value.
Keywords
Gadolium content; 1mmol/mL MR contrast agents; Myocardial viability; Delayed hyperenhancement imaging; Cardiac MRI;
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Times Cited By KSCI : 4  (Citation Analysis)
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