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http://dx.doi.org/10.5762/KAIS.2013.14.11.5646

Effects of Hot-Water Extract of Mulberry Leaf Tea Fermented by Monascus pilosus on Body Weight and Hepatic Antioxidant Enzyme Activities in Mouse Fed a Normal Diet  

Lee, Sang-Il (Department of Food, Nutrition and Culinary Arts, Keimyung College)
Lee, Ye-Kyung (Division of Bioscience and Bioinformatics, Myongji University)
Kim, Soon-Dong (Division of Bioscience and Bioinformatics, Myongji University)
Lee, In-Ae (Division of Bioscience and Bioinformatics, Myongji University)
Choi, Jongkeun (Department of Cosmetic Science, Chungwoon University)
Suh, Joo-Won (Division of Bioscience and Bioinformatics, Myongji University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.14, no.11, 2013 , pp. 5646-5657 More about this Journal
Abstract
In this study, to evaluate the anti-obesity effects of mulberry leaf tea and its fermented product by Monascus pilosus, we investigated body and organ weight, blood and liver biomarkers in mice fed 1% tea infusions instead of water for 8 weeks. Mice were divided into three groups such as a normal control (NC), unfermented mulberry leaf tea infusion (UMI) and fermented mulberry leaf tea infusion (FMI). Although it is not significant, tea infusion groups showed reduction of body weight gains compared with NC group. Moreover, contents of LDL-cholesterol and lipid peroxide (LPO), altherogenic index, and xanthin oxidase (XO) activity were significantly decreased, and glutathione S-transferase (GST) activity was significantly elevated. The results from this study suggested that UMI and FMI may have an anti-obesity activity, upregulate antioxidant enzymes and reduce levels of oxidants related to liver damage.
Keywords
Antiobese; Fermentation; Monascus pilosuss; Mulberry leaf tea; ROS-scavenging enzymes;
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