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http://dx.doi.org/10.5762/KAIS.2012.13.8.3561

The Effects of Mulberry Extract Consumption on the Serum Levels of Oxidant and Inflammatory Factors in Middle-aged Women with Rheumatoid Factors  

Shin, Jung-Hee (Department of Food & Nutrition, Joongbu University)
Han, Se-Mi (The Graduate School of Alternative Medicine of Kyonggi University)
Kim, Ae-Jung (The Graduate School of Alternative Medicine of Kyonggi University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.13, no.8, 2012 , pp. 3561-3569 More about this Journal
Abstract
This study investigated the effect of mulberry fruit extract(MFE) on antioxidant and anti-inflammatory activities of middle aged women with rheumatoid factor (RF). Thirty two middle-aged subjects were divided into two groups which were normal middle-aged group (NMG) and abnormal middle-aged group whose serum RF level were > 10 u/mL (AMG). All groups had consumed MFE (100 mL/day) for 4 weeks. Anthropometric measurements, serum inflammatory factors, serum oxidative stress markers analyses were performed at baseline and then at 4 weeks following the study. There were no significant differences in anthropometric measurements, including BMI, WHR and body fat composition between two groups. But after 4 weeks MFE consumption, serum levels of C-reactive protein (CRP), ferric-reducing ability of plasma (FRAP), serum TNF-${\alpha}$, IL-2, IL-4 had significantly decreased (p<0.05) in AMG. These findings suggested that the MFE consumption as food may be protective against oxidation and inflammation like RA.
Keywords
Anti-Inflammation; Antioxidant Activities; Mulberry Extract; Rheumatoid Factor;
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