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http://dx.doi.org/10.5762/KAIS.2012.13.12.5931

Usefulness of the PRESS Technique using 3.0T Magnetic Resonance Spectroscopy for Evaluation of Non-Alcoholic Fatty Liver Disease Patients  

Goo, Eun-Hoe (Department of Radiological Science, Cheongju University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.13, no.12, 2012 , pp. 5931-5936 More about this Journal
Abstract
This study was to evaluate the clinical usefulness of the PRESS technique based on the correlation between PRESS technique and biopsy results by applying 3.0T high magnetic field MRS technique for evaluation of non-alcoholic fatty liver disease patients. This experiment were carried out using a 3.0T magnetic resonance imaging equipment. The part data of each spectrum is taken by peak area integration. The part data of resonance peak was used to calculate relative ratio. MR spectral peak in patients with non-alcoholic fatty liver disease is from 0.9 to 1.6 ppm. According to MRS method study result, Patients with NAFLD were obtained with 94% sensitivity and 80% specificity(p=0.000). When compared to normal based on MRS and Biopsy results was valid correlation(r=0.79, p=0.04). Results for NAFLD(r=0.89, p=0.002) also showed a correlation. Therefore, PRESS technique to evaluate patients with non-alcoholic fatty liver disease, the distribution difference between normal liver and fatty liver part is significantly distinguished. Biopsy and MRS fatty liver peak ratio(%) proves high lipid over grade(r = 0.7).
Keywords
Contrast to Noise Ratio; Diffusion Weighted Image; Diffusion Tensor Image; Signal to Noise Ratio;
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