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http://dx.doi.org/10.5762/KAIS.2011.12.10.4450

Comparison of characteristics of xylitol-sensitive and xylitol-resistant Streptococcus mutans by use of various carbohydrates  

Kim, Ji-Hye (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University)
Lee, Young-Eun (Dept. of Dental Hygiene, Daegu Health College)
Ahn, Sang-Hun (Dept. of Dental Hygiene, Daegu Health College)
Choi, Youn-Hee (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University)
Song, Keun-Bae (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.12, no.10, 2011 , pp. 4450-4458 More about this Journal
Abstract
The aim of this study was to investigate the capacity of the xylitol-sensitive(Xs) and xylitol-resistant(Xr) S. mutans to induce dental caries in the presence of various carbohydrate. S. mutans KCTC3065 was cultured with 0.4% glucose and 1% xylitol in TYE medium for 30 days at $37^{\circ}C$, 10% $CO_2$ to form Xr S. mutans. Both Xs and Xr strains were cultured in four different carbohydrate environments; 0.5% glucose containing basal culture TYE medium(G-TYE), G-TYE plus 0.5% sucorse, G-TYE plus 0.5% fructose, G-TYE plus 0.5% maltose. Then cell growth, acid production, and extracellular polysaccharides synthesis were analyzed. The final growth level and extracellular polysaccharides contents in the Xr strain were significantly lower than in the Xs strain in all carbohydrates except fructose. While, acid production was no significantly difference between Xs and Xr strain. These results indicate that the virulence of Xr strains is significantly lower than that of Xs strains, which supports Xr strains may be less cariogenic than Xs strains.
Keywords
Carbohydrates; Resistance; Streptococcus mutans;
Citations & Related Records
Times Cited By KSCI : 4  (Citation Analysis)
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