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http://dx.doi.org/10.5762/KAIS.2011.12.10.4434

Antioxidant activity of wood vinegar by bioconversion  

Cho, Young-Ho (Department of Pharmaceutical Engineering, Konyang University)
Cho, Jae-Soo (Department of Pharmaceutical Engineering, Konyang University)
Lee, Gye-Won (Department of Pharmaceutical Engineering, Konyang University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.12, no.10, 2011 , pp. 4434-4442 More about this Journal
Abstract
Reactive oxygen species (ROS) are reactive and potentially harmful to cells, causing oxidation of lipids, proteins, and DNA. In humans, the deleterious effects of ROS have been linked with aging, carcinogenesis, and atherosclerosis. In order to investigate an antioxidant activity of wood vinegar by bioconversion, we preferentially analyzed the total acidity, acetic acid, pH, and contents of total polyphenols and flavonoids, respectively. Also, we evaluated the scavenging abilities on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, superoxide anion radicals, hydrogen peroxide radicals, and nitric oxide radicals. The total acidity and amount of acetic acid of wood vinegar after bioconversion were lower than those of wood vinegar before bioconversion, but the pH was higher than that of wood vinegar before bioconversion. The contents of total polyphenols and flavonoids of wood vinegar after bioconversion were 11.17 mg/$m{\ell}$ and 0.42 mg/$m{\ell}$, respectively. The $SC_{50}$ values were in order of superoxide anion radical scavenging activity < DPPH radical scavenging activity < hydrogen peroxide radical scavenging activity < nitric oxide radical scavenging activity. Therefore, these results suggest that wood vinegar by bioconversion can be useful as primary antioxidants for medicines and cosmetics.
Keywords
Wood vinegar; Bioconversion; Antioxidant; Radical scavenging activity; Reactive oxygen species;
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