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http://dx.doi.org/10.5762/KAIS.2010.11.12.4854

Synthesis and Phytophathogenic Activities of Isopropylmethylphenyl benzenesulfonate Derivatives  

Choi, Won-Sik (Department of Biotechnology, Soonchunhyang University)
Nam, Seok-Woo (Department of Biotechnology, Soonchunhyang University)
Kim, Hak-Cheun (Kyongbo Pharm)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.11, no.12, 2010 , pp. 4854-4862 More about this Journal
Abstract
Twenty five compounds isopropylmethylphenyl benzenesulfonate derivatives of thymol (1), 4-isopropyl-3-methylphenol (2), 5-isopropyl-3-methylphenol (3), 4-isopropylphenol (4), and 2-isopropylphenol (5) derivatives were synthesized. These compounds were analyzed for their structural confirmation with IR, GC/MS, and $^1H$-NMR. Synthetic compounds were tested against phytopathogenic fungi activities such as Pyrcularia grisea, Rhizoctonia solani, Phytophthora infestans, Colletotrichum orbiculare, and Sphaerotheca fusca. 2-Isopropyl-5-methylphenyl o-toluenesulfonate (1a), 2-isopropylphenyl 2,4,5-trichloro-benzenesulfonate (5b) and 2-isopropylphenyl 2-methyl-5-nitrobenzenesulfonate (5e) showed a potent in vivo antifungal activity against Pyrcularia grisea, Phytophthora infestans and Sphaerotheca fusca.
Keywords
Isopropylmethylphenyl benzenesulfonate derivatives; Phytopathogen; Fungicidal activity;
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Times Cited By KSCI : 5  (Citation Analysis)
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