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http://dx.doi.org/10.5762/KAIS.2010.11.11.4427

Suppressive effect of electrolyzed reduced water on the paraben-induced DNA damage in human dermal fibroblast cells  

Yu, A-Reum (Department of Medical Biotechnology, Soonchunhyang University)
Ryoo, Kun-Kul (Department of Display Materials Engineering, Soonchunhyang University)
Lee, Mi-Young (Department of Medical Biotechnology, Soonchunhyang University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.11, no.11, 2010 , pp. 4427-4432 More about this Journal
Abstract
Parabens have been widely used as preservatives in cosmetics due to the presumed low toxicity and long history of safe use. However, recent studies have shown the potent toxicity of parabens. In order to know if electrolyzed reduced water could suppress the oxidative DNA damage of HDF cell by methylparaben, one of the frequently used parabens, we performed comet assay in this study. As a result, interestingly, electrolyzed reduced water could suppress methylparaben-induced oxidative DNA damage in HDF cells.
Keywords
Methylparaben; Electrolyzed-reduced water; Comet assay; HDF cell;
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Times Cited By KSCI : 2  (Citation Analysis)
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