Hypoxic condition enhances chondrogenesis in synovium-derived mesenchymal stem cells |
Bae, Hyun Cheol
(Department of Orthopedic Surgery, Seoul National University Hospital)
Park, Hee Jung (Department of Orthopedic Surgery, Seoul National University Hospital) Wang, Sun Young (Department of Orthopedic Surgery, Seoul National University Hospital) Yang, Ha Ru (Department of Orthopedic Surgery, Seoul National University Hospital) Lee, Myung Chul (Department of Orthopedic Surgery, Seoul National University Hospital) Han, Hyuk-Soo (Department of Orthopedic Surgery, Seoul National University Hospital) |
1 | Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the method. Methods. 2001;25:402-8. DOI |
2 | Shang J, Liu H, Li J, Zhou Y. Roles of hypoxia during the Chondrogenic differentiation of mesenchymal stem cells. Methods. 2014;9:141-7. |
3 | Han H-S, Lee S, Kim JH, Seong SC, Lee MC. Changes in Chondrogenic phenotype and gene expression profiles associated with the in vitro expansion of human synovium-derived cells. J Orthop Res. 2010;28:1283-91. DOI |
4 | Werb Z, Chin JR. Extracellular matrix remodelling during morphogenesis. Ann N Y Acad Sci. 1998;857:110-8. DOI |
5 | Hofbauer K, Gess B, Lohaus C, Meyer H, Katschinski D, Kurtz A. Oxygen tension regulates the expression of a group of procollagen hydroxylases. Eur J Biochem. 2003;270:4515-22. DOI |
6 | Takahashi Y, Takahashi S, Shiga Y, Yoshimi T, Miura T. Hypoxic induction of prolyl 4-hydroxylase alpha (I) in cultured cells. J Biol Chem. 2000;275:14139-46. DOI |
7 | Kubosch EJ, Lang G, Furst D, Kubosch D, Izadpanah K, Rolauffs B, Sudkamp NP, Schmal H. The potential for synovium-derived stem cells in cartilage repair. Curr Stem Cell Res Ther. 2018;13:174-84. DOI |
8 | Pastides P, Chimutengwende-Gordon M, Maffulli N, Khan W. Stem cell therapy for human cartilage defects: a systematic review. Osteoarthr Cartil. 2013;21:646-54. DOI |
9 | Bornes TD, Adesida AB, Jomha NM. Mesenchymal stem cells in the treatment of traumatic articular cartilage defects: a comprehensive review. Arthritis Res Ther. 2014;16:432. DOI |
10 | Sakaguchi Y, Sekiya I, Yagishita K, Muneta T. Comparison of human stem cells derived from variousmesenchymal tissues: superiority of synovium as a cell source. Arthritis Rheum. 2005;52:2521. DOI |
11 | Yusuke O, Yo M, Mayu Y, Eriko GS, Nobuharu S, Takeshi M, Ichiro S, Chihiro A. Purified human synovium mesenchymal stem cells as a good resource for cartilage regeneration. PLoS One. 2015;10:e129096. |
12 | Das R, et al. The role of hypoxia in bone marrow-derived mesenchymal stem cells: considerations for regenerative medicine approaches. Tissue Eng Part B Rev. 2010;16:159. DOI |
13 | Danisovica L, Varga I, Polakc S. Growth factors and chondrogenic differentiation of mesenchymal stem cells. Tissue Cell. 2012;44:69-73. DOI |
14 | Rodrigo AS, Jean FW, Diego C, Arnold IC. Chondrogenic differentiation of mesenchymal stem cells: challenges and unfulfilled expectations. Tissue Eng Part B Rev. 2014;20:596-608. DOI |
15 | Chiou SH, et al. Identification of CD133-positive radioresistant cells in atypical teratoid/rhabdoid tumor. PLoS One. 2008;3:e2090. DOI |
16 | Kim DS, et al. Effect of low oxygen tension on the biological characteristics of human bone marrow mesenchymal stem cells. Cell Stress Chaperones. 2016;21:1089-99. DOI |
17 | Paquet J, Deschepper M, Moya A, Logeart-Avramoglou D, Boisson-Vidal C, Petite H. Oxygen tension regulates human mesenchymal stem cell paracrine functions. Stem Cells Transl Med. 2015;4:809-21. DOI |
18 | Roy S, Tripathy M, Mathur N, Jain A, Mukhopadhyay A. Hypoxia improves expansion potential of human cord blood-derived hematopoietic stem cells and marrow repopulation efficiency. Eur J Haematol. 2012;88:396-405. DOI |
19 | Lafont JE. Lack of oxygen in articular cartilage: consequences for chondrocyte biology. Int J Exp Pathol. 2010;91:99-106. DOI |
20 | Fermor B, Christensen SE, Youn I, Cernanec JM, Davies CM, Weinberg JB. Oxygen, nitric oxide and articular cartilage. Eur Cell Mater. 2007;13:56-65. DOI |
21 | Lafont JE, Talma S, Murphy CL. Hypoxia-inducible factor 2alpha is essential for hypoxic induction of the human articular chondrocyte phenotype. Arthritis Rheum. 2007;56:3297-306. DOI |
22 | Shang J, Liu H, Li J, Zhou Y, Fermor B, Gimble JM, Awad HA, Guilak F. Roles of hypoxia during the chondrogenic differentiation of mesenchymal stem cells. Curr Stem Cell Res Ther. 2014;9:141-7. DOI |
23 | Scherer K, Schunke M, Sellckau R, Hassenpflug J, Kurz B. The influence of oxygen and hydrostatic pressure on articular chondrocytes and adherent bone marrow cells in vitro. Biorheology. 2004;41:323-33. |
24 | Lee S, Kim JH, Jo CH, Seong SC, Lee JC, Lee MC. Effect of serum and growth factors on chondrogenic differentiation of synoviumderived stromal cells. Tissue Eng Part A. 2009;15(11):3401-15. DOI |
25 | Hunziker EB. Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. Osteoarthr Cartil. 2002;10:432. DOI |
26 | Lee JW, Kim YH, Kim SH, Han SH, Hahn SB. Chondrogenic differentiation of mesenchymal stem cells and its clinical applications. Yonsei Med J. 2004;45(Suppl):41-7. DOI |
27 | Kadiyala S, Young RG, Thiede MA, Bruder SP. Culture expanded canine mesenchymal stem cells possess osteochondrogenic potential in vivo and in vitro. Cell Transplant. 1997;6(2):125-34. DOI |
28 | Archer CW, Dowthwaite GP, Francis-West P. Development of synovial joints. Birth Defects Res C Embryo Today. 2003;69:144. DOI |
29 | Meirelles Lda S, Nardi NB. Murine marrow-derived mesenchymal stem cell: isolation, in vitro expansion, and characterization. Br J Haematol. 2003;123(4):702-11. DOI |
30 | Fan J, Varshney RR, Ren L, Cai D, Wang DA. Synovium-derived mesenchymal stem cells: a new cell sourcefor musculoskeletal regeneration. Tissue Eng Part B Rev. 2009;15:75. |
31 | Kim JH, Lee MC, Seong SC, Park KH, Lee S. Enhanced proliferation and chondrogenic differentiation of human synovium-derived stem cells expanded with basic fibroblast growth factor. Tissue Eng Part A. 2011;17:991. DOI |
32 | Kanichai M, Ferguson D, Prendergast PJ, Campbell VA. Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: a role for AKT and hypoxiainducible factor (HIF)-1alpha. J Cell Physiol. 2008;216(3):708-15. DOI |
33 | Khan WS, Adesida AB, Tew SR, Lowe ET, Hardingham TE. Bone marrowderived mesenchymal stem cells express the pericyte marker 3G5 in culture and show enhanced chondrogenesis in hypoxic conditions. J Orthop Res. 2010;28(6):834-40. DOI |
34 | Khan WS, Adesida AB, Hardingham TE. Hypoxic conditions increase hypoxiainducible transcription factor and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients. Arthritis Research & Therapy. 2007;9:R55. DOI |
35 | Baumgartner L, Arnhold S, Brixius K, Addicks K, Bloch W. Human mesenchymal stem cells: influence of oxygen pressure on proliferation and chondrogenic differentiation in fibrin glue in vitro. J Biomed Mater Res A. 2010;93(3):930-40. |