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http://dx.doi.org/10.13106/kjfhc.2022.vol8.no5.21.

Pharmacological Viewpoint Concerns and Phytochemical Components of Ginseng  

RANA, Anvi (Department of Food Technology and Nutrition, Lovely Professional University)
Publication Information
The Korean Journal of Food & Health Convergence / v.8, no.5, 2022 , pp. 21-28 More about this Journal
Abstract
Ginseng is described as the "King of all herbs, "Man-root" or "Root of heaven" and regarded as the most powerful herbal remedy, particularly grown in Korea, China, Japan, Vietnam, and North America. It has been in existence for a long time. The most demanded herbal cure, Ginseng, principally the root, has long been employed in traditional Asian medicine. The extent of availability of bioactive combinations and their impact on the body differs between American and Asian ginseng. Asian ginseng, also known as Panax ginseng, has a more calming influence and is more advantageous than American ginseng, such as Panax quinquefolius. The pharmaceutical aspect of development and extraction with diverse morphological properties is examined. Saponins, glycosides, carbohydrates, polyacetylenes, amino acids, vitamins, volatile oil, enzymes are all present in the Phyto-content of Ginseng. Ginsenosides are saponins that are constituents of the triterpenoid dammarane and have anticancer, anti-cardiovascular, anti-microbial, anti-obesity, anti-inflammatory, and antioxidant properties. Ginseng, in particular, has the possibility to help with microbial invasion, inflammatory processes, oxidative stress, and diabetes. It developed nanoparticles and nanocomposite film technologies as novel drug delivery platforms for cancer, inflammation, and neurological illnesses. Furthermore, it offers a range of applications that will be vital for future growth.
Keywords
Ginseng; Remedial; Phytonutrients; Health benefits; Pharmacological;
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Times Cited By KSCI : 6  (Citation Analysis)
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1 Kim, J. H. (2018). Pharmacological and medical applications of Panax ginseng and ginsenosides: a review for use in cardiovascular diseases. J Ginseng Res 42 (3): 264-269.   DOI
2 Choi, K. T. (2008). Botanical characteristics, pharmacological effects and medicinal components of Korean Panax ginseng CA Meyer. Acta Pharmacologica Sinica, 29(9), 1109-1118.   DOI
3 Fan, T. P., Deal, G., Koo, H. L., Rees, D., Sun, H., Chen, S., & Chan, K. (2012). Future development of global regulations of Chinese herbal products. Journal of ethnopharmacology, 140(3), 568-586.   DOI
4 Kim, Y. J., Yamabe, N., Choi, P., Lee, J. W., Ham, J., & Kang, K. S. (2013). Efficient thermal deglycosylation of ginsenoside Rd and its contribution to the improved anticancer activity of ginseng. Journal of agricultural and food chemistry, 61(38), 9185-9191.   DOI
5 Kang, O. J., & Kim, J. S. (2016). Comparison of ginsenoside contents in different parts of Korean ginseng (Panax ginseng CA Meyer). Preventive nutrition and food science, 21(4), 389.   DOI
6 Xu, L. L., Han, T., Wu, J. Z., Zhang, Q. Y., Zhang, H., Huang, B. K., & Qin, L. P. (2009). Comparative research of chemical constituents, antifungal and antitumor properties of ether extracts of Panax ginseng and its endophytic fungus. Phytomedicine, 16(6-7), 609-616   DOI
7 Yeo, C. R., Yong, J. J., & Popovich, D. G. (2017). Isolation and characterization of bioactive polyacetylenes Panax ginseng Meyer roots. Journal of Pharmaceutical and Biomedical Analysis, 139, 148-155.   DOI
8 Zheng, Y., Lee, J., Lee, E. H., In, G., Kim, J., Lee, M. H., & Kang, I. J. (2020). A Combination of Korean Red Ginseng Extract and Glycyrrhiza glabra L. Extract Enhances Their Individual Anti-Obesity Properties in 3T3-L1 Adipocytes and C57BL/6J Obese Mice. Journal of medicinal food, 23(3), 215-223.   DOI
9 Chong-Zhi, W., Anderson, S., Wei, D. U., Tong-Chuan, H. E., & Chun-Su, Y. (2016). Red ginseng and cancer treatment. Chinese journal of natural medicines, 14(1), 7-16.   DOI
10 Wang, L., Huang, Y., Yin, G., Wang, J., Wang, P., Chen, Z. Y., & Ren, G. (2020). Antimicrobial activities of Asian ginseng, American ginseng, and notoginseng. Phytotherapy Research, 34(6), 1226-1236.   DOI
11 Lee, M. H., Kim, S. S., Cho, C. W., Choi, S. Y., In, G., & Kim, K. T. (2013). Quality and characteristics of ginseng seed oil treated using different extraction methods. Journal of Ginseng Research, 37(4), 468.   DOI
12 Hong, H., Baatar, D., & Hwang, S. G. (2021). Anticancer activities of ginsenosides, the main active components of ginseng. Evidence-Based Complementary and Alternative Medicine, 2021.
13 Kitts, D. D., Wijewickreme, A. N., & Hu, C. (2000). Antioxidant properties of a North American ginseng extract. Molecular and cellular biochemistry, 203(1), 1-10.   DOI
14 Kim, J. S. (2016). Investigation of phenolic, flavonoid, and vitamin contents in different parts of Korean ginseng (Panax ginseng CA Meyer). Preventive nutrition and food science, 21(3), 263.   DOI
15 Kim, J. H., Yi, Y. S., Kim, M. Y., & Cho, J. Y. (2017). Role of ginsenosides, the main active components of Panax ginseng, in inflammatory responses and diseases. Journal of ginseng research, 41(4), 435-443.   DOI
16 Kiefer, D. S., & Pantuso, T. (2003). Panax ginseng. American family physician, 68(8), 1539-1542.
17 Li, X., Chu, S., Lin, M., Gao, Y., Liu, Y., Yang, S., & Chen, N. (2020). Anticancer property of ginsenoside Rh2 from ginseng. European Journal of Medicinal Chemistry, 203, 112627.   DOI
18 Park, E. Y., Kim, M. H., Kim, E. H., Lee, E. K., Park, I. S., Yang, D. C., & Jun, H. S. (2014). Efficacy comparison of Korean ginseng and American ginseng on body temperature and metabolic parameters. The American journal of Chinese medicine, 42(01), 173-187.   DOI
19 Shi, Z. Y., Zeng, J. Z., & Wong, A. S. T. (2019). Chemical structures and pharmacological profiles of ginseng saponins. Molecules, 24(13), 2443.   DOI
20 Wu, J., Lin, L., & Chau, F. T. (2001). Ultrasound-assisted extraction of ginseng saponins from ginseng roots and cultured ginseng cells. Ultrasonics sonochemistry, 8(4), 347-352.   DOI
21 Yang, Y., Ren, C., Zhang, Y., & Wu, X. (2017). Ginseng: an nonnegligible natural remedy for healthy aging. Aging and disease, 8(6), 708.   DOI
22 Cho, E. J., Piao, X. L., Jang, M. H., Baek, S. H., Kim, H. Y., Kang, K. S., & Park, J. H. (2008). The effect of steaming on the free amino acid contents and antioxidant activity of Panax ginseng. Food Chemistry, 107(2), 876-882.   DOI
23 Saldanha, C. W., Otoni, C. G., de Azevedo, J. L. F., Dias, L. L. C., do Rego, M. M., & Otoni, W. C. (2012). A low-cost alternative membrane system that promotes growth in nodal cultures of Brazilian ginseng [Pfaffia glomerata (Spreng.) Pedersen]. Plant Cell, Tissue and Organ Culture (PCTOC), 110(3), 413-422   DOI
24 Baek, K. S., Yi, Y. S., Son, Y. J., Yoo, S., Sung, N. Y., Kim, Y. & Cho, J. Y. (2016). In vitro and in vivo anti-inflammatory activities of Korean Red Ginseng-derived components. Journal of Ginseng Research, 40(4), 437-444.   DOI
25 Baek, S. H., Bae, O. N., & Park, J. H. (2012). Recent methodology in ginseng analysis. Journal of Ginseng Research, 36(2), 119.   DOI
26 Baeg, I. H., & So, S. H. (2013). The world ginseng market and the ginseng (Korea). Journal of ginseng research, 37(1), 1.   DOI
27 Coon, J. T., & Ernst, E. (2002). Panax ginseng. Drug safety, 25(5), 323-344.   DOI
28 Dharmananda, S. (2002). The Nature of Ginseng from Traditional Use to Modern Research. ITM.
29 Hankins, A. G. (2000). Producing and marketing wild simulated ginseng in forest and agroforestry systems.
30 Hu, S. Y. (1977). A contribution to our knowledge of ginseng. The American Journal of Chinese Medicine, 5(01), 1-23.   DOI
31 Hofseth, L. J., & Wargovich, M. J. (2007). Inflammation, cancer, and targets of ginseng. The Journal of nutrition, 137(1), 183S-185S.   DOI
32 Jung, S. J., Yoon, E. S., Jeong, J. H., & Choi, Y. E. (2004). Enhanced post-germinative growth of encapsulated somatic embryos of Siberian ginseng by carbohydrate addition to the encapsulation matrix. Plant cell reports, 23(6), 365-370.   DOI
33 Qiu, Y., Lu, X., Pang, T., Ma, C., Li, X., & Xu, G. (2008). Determination of radix ginseng volatile oils at different ages by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry. Journal of separation science, 31(19), 3451-3457.   DOI
34 Lum, J. H. K., Fung, K. L., Cheung, P. Y., Wong, M. S., Lee, C. H., Kwok, F. S. L., & Lo, S. C. L. (2002). Proteome of Oriental ginseng Panax ginseng CA Meyer and the potential to use it as an identification tool. PROTEOMICS: International Edition, 2(9), 1123-1130.   DOI
35 Lee, S. D., Yoo, G., Chae, H. J., In, M. J., Oh, N. S., Hwang, Y. K., & Kim, D. C. (2009). Lipid-soluble extracts as the main source of anticancer activity in ginseng and ginseng marc. Journal of the American Oil Chemists' Society, 86(11), 1065-1071.   DOI
36 Lee, J. H., Kim, S. C., Lee, H. Y., Cho, D. Y., Jung, J. G., Kang, D., & Cho, K. M. (2021). Changes in nutritional compositions of processed mountain-cultivated ginseng sprouts (Panax ginseng) and screening for their antioxidant and anti-inflammatory properties. Journal of Functional Foods, 86, 104668   DOI
37 Rokot, N. T., Kairupan, T. S., Cheng, K. C., Runtuwene, J., Kapantow, N. H., Amitani, M., & Inui, A. (2016). A role of ginseng and its constituents in the treatment of central nervous system disorders. Evidence-Based Complementary and Alternative Medicine, 2016.
38 Sook, Y. L., Yong, K. K., Nam, I. P., Chun, S. K., Chung, Y. L., & Sang, U. P. (2010). Chemical constituents and biological activities of the berry of Panax ginseng. Journal of Medicinal Plants Research, 4(5), 349-353.