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A clinical analysis of uterine myoma  

Park, Jeong-Kuy (Department of Obstetrics and Gynecology, Chonbuk National University Medical School)
Yoon, Seok-Geun (Department of Obstetrics and Gynecology, Chonbuk National University Medical School)
Kim, Sung-Ug (Department of Obstetrics and Gynecology, Chonbuk National University Medical School)
Lee, Jeong-Heon (Department of Obstetrics and Gynecology, Chonbuk National University Medical School)
Kim, Jong-Hyeon (Department of Obstetrics and Gynecology, Chonbuk National University Medical School)
Yi, Seung-Yeun (Department of Obstetrics and Gynecology, Chonbuk National University Medical School)
Jeong, So-Mang (Department of Obstetrics and Gynecology, Chonbuk National University Medical School)
Rheu, Chul-Hee (Department of Obstetrics and Gynecology, Chonbuk National University Medical School)
Kim, Jong-Duk (Department of Obstetrics and Gynecology, Chonbuk National University Medical School)
Publication Information
Obstetrics & gynecology science / v.48, no.2, 2005 , pp. 436-445 More about this Journal
Abstract
From January 1998 to December 2002, 3,259 cases of uterine myoma were treated at the department of Obstetrics and Gynecology, Chunbuk National University Hospital. A clinico-stastical study of uterine myoma was perfomed to analyse the clinical characteristics. The results were as follows. 1. The incidence of uterine myoma was 9.8%. 2. The most frequent age group was 40 to 49 years, and the mean age was 44.6 years. 3. The average parity was 2.29, the infertility was 163 cases (5.0%), while the primary infertility, 2.4%, the secondary, 2.6% respectively. 4. The most frequent chief complaint was pain which was observed in 2,648 cases (81.2%), abnormal bleeding in 1,775 cases (53.8%). dizziness in 270 cases (8.3%). 5. The corporeal myomas were observed in 2,879 cases (95.9%). Intramural type was observed in 1,687 cases (58.2%), subserous in 529 cases (18.2%), submucous in 191 cases (6.5%), mixed type in 483 cases (17.0%). 6. The mean value of preoperative hemoglobin was 11.1 gm/dL, and the anemia (Hb<10.0 gm/dL) was observed in 481 cases (11.7%). Transfusion was necessary in 215 cases (6.5%). 7. The mean weight of the uterine myoma operated was 335.0 gm. 8. The secondary change of myoma was found in 54 cases (1.7%) and hyaline degeneration was the most common (0.7%). 9. The most common associated condition was chronic cervicitis, which was observed in 784 cases (24.1%). 10. The gynecologic surgery were performed in 1,456 cases (44.7%), medical therapy in 25 cases (0.8%), observation in 1,792 cases (55.0%). 11. Total abdominal hysterectomy was performed in 607 cases (41.7%), total abdominal hysterectomy with unilateral adnexectomy in 115 cases (7.9%), total abdominal hysterectomy with both adnexectomy in 164 cases (11.3%), subtotal hysterectomy in 304 cases (20.9%), myomectomy in 153 cases (10.5%), total laparoscopic hysterectomy in 103 cases (7.0%), laparoscopy assisted vaginal hysterectomy in 8 cases (0.5%), diagnostic laparoscopy in 2 cases (0.1%) respectively. 12. The postoperative complication were found in 113 cases (3.5%) and the wound infection was the most common (1.6%). 13. The mean period of hospitalization was 8 days, and the period less than 10 days in 1,177 cases (80.9%).
Keywords
Uterine myoma;
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Times Cited By KSCI : 1  (Citation Analysis)
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1 이란옥, 박경일, 깅종철, 박무실, 김철, 지정희. 자궁근종에 대한 임상통계학적 관찰. 대한산부회지 1994; 37: 2216
2 Babaknia A, Rock JA, Jones HW. Pregnancy success following abdominal myomectomy for infertility. Fertil Steril 1978; 30: 644   DOI   PUBMED
3 Coutinho EM, Concalves MT, Long-term treatment of leiomyomas with gestrinone. Fertil Steril 1989; 51: 939-46   DOI   PUBMED
4 Letterie GS, Coddington CC, Winkel CA, Shawker TH, Loriaux DL, Collins RL. Efficacy of a GnRH agonist in the treatment of uterine leiomyoma: long-term follow-up. Fertil Steril 1989; 51: 951
5 Parker WH, Fu YS, Berek JS. Uterine sarcoma in patients operated on for presumed leiomyoma and rapidly growing leiomyoma. Obstet Gynecol 1994; 83: 414-8   PUBMED
6 Harrison-Woolrych ML, Sharkey AM, Charnock-Jones DS, Smith SK. Localization and quantification of vascular endothelial growth factor messenger ribonucleic acid in human myometrium and leiomyomata. J Clin Endocrinol Metab 1995; 80: 1853-8   DOI   ScienceOn
7 Leibsohn S, d'Ablaing G, Mishell DR Jr, Schlaerth JB. Leiomyosarcoma in a series of hysterectomies performed for presumed uterine leiomyomas. Am J Obstet Gynecol 1990; 162: 968-74   DOI   PUBMED   ScienceOn
8 Paraziini F, La Vecchia C, Negri E, Cecchetti G, Fedele L. Epidemiologic characteristics of women with uterine fibroids: a case-control study. Obstet Gynecol 1988; 72: 853-7   DOI   PUBMED
9 Clapp C, Martial JA, Guzman RC, et al. The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis. Endocrinology 1993; 133: 1292-9   DOI   PUBMED   ScienceOn
10 Buttram VC Jr, Reiter RC. Uterine leiomyoma: Etiology, symptomatology, and management. Fertil Steril 1981; 36: 433   DOI   PUBMED
11 Matta WH, Shaw RW, Nye M. Long-term follow-up of patients with uterine fibroids after treatment with the LHRH agonist buserelin. Br J Obstet Gynecol 1989; 96: 200
12 Marshall LM, Spiegelman D, Barbieri RL, Goldman MB, Manson J, Colditz GA, et al. Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstet Gynecol 1997; 90; 967-73   DOI   ScienceOn
13 Deligdish L, Loewenthal M. Endometrial Changes associated with myomata of the uterus. J Clin Pathol 1970; 23: 676   DOI   PUBMED
14 Stewart EA, Nowak RA. Leiomyoma-related bleeding: a classic hypothesis updated for the molecular era. Hum Reprod Update 1996; 2: 295-306   DOI   ScienceOn
15 Mangrulkar RS, Ono .M, Ishikawa M, Takashima S, Klagsbrun M, Nowak RA. Isolation and characterization of heparin-binding growth factors in human leiomyomas and normal myometrium. Biol Reprod 1995; 53; 636-46   DOI   ScienceOn
16 Minakuchi K, Kawamura N, Tsujimura A, Ogita S. Remarkable and persistent shrinkage of uterine leiomyoma associated with interferon alfa treatment of hepatitis. Lancet 1999; 363: 2127-8
17 Coutinho EM, Maia HS. The contractile response of the human uterus, fallopian tubes, and ovary to prostaglandines in vivo. Fertil Steril 1971; 22: 539-43   DOI   PUBMED
18 Sampson JA. The blood supply of uterine myomata. Surg Gynecol Obstet 1912; 14: 215-30
19 김동호, 김흥관, 선진규, 박병삼, 임헌정. 자궁근종에 대한 임상 및 병리학적 연구. 대한산부회지 1994; 37: 1205
20 Folkman J. Clinical applications of research on angiogenesis. N Engl J Med 1995; 333: 1757-63   DOI   ScienceOn
21 Hunt JE, Wallach EE. Uterine factors in infertility; an overview. Clinical Obstet Gynecol 1974; 17: 44-64   DOI   ScienceOn
22 백원민, 정승우, 조성식, 임광호. 자궁근종의 임상적 고찰. 대한산부회지 1983; 20: 1047
23 Murphy AA, Morales AJ, Kettel LM, Yen SS. Regression of uterine leiomyomata to the antiprogesterone RU486: dose-response effect. Fertil Steril 1995; 64: 187-90   PUBMED
24 육순광, 정기성, 이숙환, 김성도, 안재영. 자궁근종의 임상병리학적 고찰. 대한산부회지 1984; 27: 1846
25 서호성, 남철, 김창수, 장병곤, 양희동, 박세준. 자궁근종에 대한 임상통계학적 연구. 대한산부회지 1996; 39; 1047
26 정진국, 고만석, 정병욱, 이호형, 최호준, 신승권. 자궁근종에 관한 임상통계학적 고찰. 대한산부회지 1998; 41: 210
27 Farrer-Brown G, Beilby JOW, Tarbit MH. Venous changes in the endometrium of myomatous uteri. Obstet. Gynecol 1971; 38: 743-51   PUBMED
28 Vollenhoven HJ, Herington AC and Healy DL. Messenger ribonucleic acid expression of the insulin-like growth factor and their binding proteins in uterine fibroids and myometrium. J Clin Endocrinol Metab 1993; 76: 1106-10   DOI   ScienceOn
29 이종학. 자궁근종에 대한 임상적 및 병리학적 연구. 대한산부회지 1987; 30: 213
30 Chiaffarino F, Paraziini F, La Vecchia C, Chatenoud L, Cintio ED, Marsico S. Diet and uterine myomas. Obstet Gynecol 1999; 94: 395-8   DOI   PUBMED   ScienceOn
31 Stewart EA. Uterine fibroids. Lancet 2001; 357: 293-8   DOI   ScienceOn
32 유한기. 자궁근종의 임상병리학적 연구. 대한산부회지 1987; 30: 1287
33 Arthur LH, Daniel RM Jr, Morton AS, Wiliam D. Comprehensive Gynecology 2nd ed. St. Louis; Mosby Year Book 1992; 182
34 Coutinho EM, Boulanger GA, Goncalves MT. Regression of uterine leiomyomas after treatment with gestrinone, an antiestrogen, antiprogesterone. Am J Obstet Gynecol 1986; 155: 761   DOI   PUBMED
35 Cramer SF, Patel A. The frequency of uterine leiomyomas. Am J Clin Pathol 1990; 94: 435-8   DOI   PUBMED
36 Goldzieher JW, Maqueo M, Ricaud L, Aguilar JA, Canales E. Induction of degenerative changes in uterine myomas by high-dosage progestin therapy. Am J Obstet Gynecol 1966; 96: 1078