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http://dx.doi.org/10.6110/KJACR.2015.27.12.645

An Experimental Study on the Freeze Drying Process for Poly γ Glutamic Acid  

Kang, Jisu (Department of Mechanical Engineering, Graduate School of Kookmin University)
Sim, Yeon-Ho (Department of Mechanical Engineering, Graduate School of Kookmin University)
Byun, Si-Ye (Department of Mechanical Engineering, Graduate School of Kookmin University)
Chang, Young Soo (School of Mechanical Systems Engineering, Kookmin University)
Kang, Byung Ha (School of Mechanical Systems Engineering, Kookmin University)
Publication Information
Korean Journal of Air-Conditioning and Refrigeration Engineering / v.27, no.12, 2015 , pp. 645-651 More about this Journal
Abstract
This paper presents an experimental study on the freeze drying process for poly ${\gamma}$ glutamic acid. The physical properties of poly ${\gamma}$ glutamic acid are measured during the freeze-drying process. The moisture contents of poly ${\gamma}$ glutamic acid according to the glass transient temperature are obtained by DSC (Differential Scanning Calorimetry) analysis. The end point of primary drying for the poly ${\gamma}$ glutamic acid with a thickness of 3 mm is obtained by measuring the thickness of the dried layer, the amount of moisture evaporation, the moisture content, and the pressure in the drying vacuum chamber during the freeze-drying process. By considering the variation in the glass transient temperature with respect to the moisture content of the material, a control schedule for the heating plate temperature is suggested during the secondary drying process.
Keywords
Vacuum freeze drying; Biomaterial; Poly ${\gamma}$ glutamic acid; Glass transient temperature;
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